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NTIS 바로가기한국콘텐츠학회논문지 = The Journal of the Korea Contents Association, v.17 no.7, 2017년, pp.648 - 663
To verify the association between GSTM1/GSTT1 gene polymorphisms and susceptibility to autoimmune diseases in Asian population. 18 published reports cited in EMBASE, Google, KISS, MEDLINE and PubMed up to December 2015 were collected for a meta-analysis. The GSTM1/GSTT1 polymorphism for null and pre...
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핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
류마티스 관절염이란 무엇인가? | 류마티스 관절염(RA, Rheumatoid arthritis)은 일반적으로 연골과 뼈 등을 점진적으로 파괴하고 활액 관절의 만성적인 염증이 특징인 면역질환이다. 정확한 원인은 알려져 있지 않지만, 유전 및 가족 연구를 통해 여러유전적 요인이 발병에 기여한다는 것을 알 수 있다[8]. | |
전신성 홍반성 루푸스는 어떠한 특성을 가지는가? | 전신성 홍반성 루푸스(SLE, Systemic Lupus Erythe matosus)는 만성 염증성 자가면역질환으로 여러 장기에 광범위하게 영향을 미치는 특성이 있다. 원인은 정확히 알려져 있지 않지만, 유전, 호르몬, 환경적 요인뿐만 아니라 타고난 면역체계와 적응면역체계의 면역이 상이 확인되었다[4]. | |
백반증의 증상으로는 무엇이 있는가? | 백반증(vitiligo)은 전 세계에 걸쳐 모든 연령대, 남녀 동등하게 특발성으로 피부의 색소가 탈색되는 비교적 흔한 질환이다. 멜라닌 세포의 손실로 피부에 생기는 얼룩이 특징적이며, 피부색은 시간이 지남에 따라 대부분 잃어버리고 서서히 사라지게 된다[17]. 멜라닌 세포의 손상이나 사망을 일으키는 원인이 무엇인지는 분명 하지 않지만 자가면역, 신경계, 자가세포독성, 생화학 적, 산화스트레스, 멜라닌 세포 출혈 및 멜라닌 세포 생존 감소와 관련된 잠재적인 병리학적 이론이 있다[18]. |
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