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NTIS 바로가기한국산학기술학회논문지 = Journal of the Korea Academia-Industrial cooperation Society, v.18 no.11, 2017년, pp.433 - 444
강선희 (공주대학교 의료정보학과) , 부유경 (을지대학교 의료경영학과) , 안병기 (우송대학교 보건의료경영학과)
This study was conducted to identify relationships between lung function disorders and Metabolic Syndrome(MetS) that have common comorbidities such as Cardio Vascular Diseases(CVD). According to the hypothesis that there may be a significant relationship between them, analyses were conducted to iden...
핵심어 | 질문 | 논문에서 추출한 답변 |
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만성 폐쇄성 폐질환이란? | 만성 폐쇄성 폐질환(COPD)은 “비가역적인 기류 제한을 특징으로 하는 폐 질환으로서 만성 염증에 의한 기도와 폐 실질 손상으로 인해 발생하는 질환”으로 정의된다[1]. 전신적인 동반질환이 발생하며 대사증후군을 비롯하여 심혈관 질환, 당뇨병, 골다공증, 우울증, 폐암 등이 있다[1,2]. | |
만성 폐쇄성 폐질환의 증상은 무엇인가? | 만성 폐쇄성 폐질환(COPD)은 “비가역적인 기류 제한을 특징으로 하는 폐 질환으로서 만성 염증에 의한 기도와 폐 실질 손상으로 인해 발생하는 질환”으로 정의된다[1]. 전신적인 동반질환이 발생하며 대사증후군을 비롯하여 심혈관 질환, 당뇨병, 골다공증, 우울증, 폐암 등이 있다[1,2]. 대사증후군은 고혈압이나, 또는 당 불내성과 이에 따른 고 인슐린 혈증이 인슐린 저항성을 가져오고 이들이 혼재되어, 중성 지방 증가, 고밀도 지단백 콜레스테롤 감소 및 고지혈증등 몇 가지가 동시에 한 사람에게 무리지어 나타나면서 2형 당뇨, 고혈압, 심혈관 질환의 위험성을 크게 증대시킨다는 특징이 있다[3]. | |
폐기능과 대사증후군과의 관계는 어떠한가? | 폐기능과 대사증후군과의 관계에서는 당뇨가 폐기능 감소와 관련 있고, 내피 세포계의 이상이 호흡기 질환, 대사증후군, 심혈관 질환과 관련이 있다는 주장[4]과 비만 세포유래 염증 세포의 증가와 염증 반응이, 인슐린 저항성을 가져오고 비만과 관련된 심혈관 질환 위험을 증대시킨다는 이론이 있다[5]. 실제 연구에 따르면 COPD 환자의 경우 대사증후군의 유병률이 높다는 연구와, 심혈관 질환이 없는 COPD 환자의 대사증후군 유병률이 일반 인구의 대사증후군 유병률과 차이가 없다는 연구가 있다[6]. |
COPD Guideline Revision Committee, COPD Guideline Revised 2014; The Korean Academy of Tuberculosis and Respiratory Diseases, Seoul, Korea, c2014[cited 2016 Aug. 23]Available from https://www.lungkorea.org/thesis/file/copd_slide_2014.pdf, (accessed Nov. 20, 2016)
Global Initiative for Chronic Obstructive Lung Disease.(GOLD): Teaching Slide Set, GOLD, [cited Jan. 2015] Available from: http://www.goldcopd.com (accessed Nov. 27, 2016)
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