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NTIS 바로가기大韓韓方小兒科學會誌 = The journal of pediatrics of Korean medicine, v.32 no.4, 2018년, pp.71 - 86
김경리 (대전대학교 한의과대학 소아과학교실) , 이진화 (대전대학교 한의과대학 소아과학교실) , 김은진 (대전대학교 한의과대학 소아과학교실) , 김윤희 (대전대학교 한의과대학 소아과학교실)
Objectives The purpose of this study is to investigate the effects of Gardenia jasminoides for. grandiflora extracts' (GAJ) anti-inflammatory effect on RBL-2H3 mast cells and OVA/alum-sensitized mice. Methods In this study, IL-4 and IL-13 production was measured via ELISA analysis, and mRNA expressi...
핵심어 | 질문 | 논문에서 추출한 답변 |
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아토피 질환의 전형적인 경과의 특징은 무엇인가? | 아토피, 알레르기 질환의 원인은 아직 정확히 밝혀지지 않았으나 환경 요인, 유전 요인, 환경 요인, 외부항원에 대한 면역 요인 등이 복합적으로 연관된다고 알려져 있다9). 알레르기의 4가지 분류 중 아토피 질환은 제 1형 즉시형 과민반응으로 그 전형적인 경과의 특징은 IgE 항체의 생산과 Th2 세포의 활성화이다10). 특히 급성 아토피 피부염은 면역학 적으로 IgE 증가, 호산구 증가, T 세포면역 반응 중 TNF-α, GM-CSF, IL-13, IL-16, IL-10, L-3, IL-5, IL-4 등의 cytokine을 분비하는 Th2 반응의 우세가 핵심 요인으로 보고되어 있다11,12). | |
梔子의 효과는 무엇인가? | grandiflora)는 꼭두서니과 (Rubiaceae)에 속하는 梔子나무 (Gardenia jasminoides Ellis)의 열매로 三焦 (上焦, 中焦, 下焦)의 火熱을 瀉하고 凉血止血調經, 淸肝하는 약재로서 淸熱瀉火藥으로 분류되고 性味는 苦寒1)하다. 또한 해열작용, 이뇨작용, 담즙분비 촉진작용, 소염작용 및 항염, 항산화2), 항균,항바이러스3), 항불안4) 등을 나타내어 황달, 간질환을 비롯한 충혈, 출혈 등의 소염 치료에 임상적으로 사용되어 왔다5). 최근에는 梔子 엑기스 및 분말을 사용한 피부 외용제 제품 개발 및 연구가 진행되어 여러 제품이 소염 치료제로 허가되어 판매되고 있다6). | |
梔子는 무엇인가? | 梔子 (Gardenia jasminoides for. grandiflora)는 꼭두서니과 (Rubiaceae)에 속하는 梔子나무 (Gardenia jasminoides Ellis)의 열매로 三焦 (上焦, 中焦, 下焦)의 火熱을 瀉하고 凉血止血調經, 淸肝하는 약재로서 淸熱瀉火藥으로 분류되고 性味는 苦寒1)하다. 또한 해열작용, 이뇨작용, 담즙분비 촉진작용, 소염작용 및 항염, 항산화2), 항균,항바이러스3), 항불안4) 등을 나타내어 황달, 간질환을 비롯한 충혈, 출혈 등의 소염 치료에 임상적으로 사용되어 왔다5). |
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