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Simultaneous determination of 14 oral antihyperglycaemic drugs in human urine by liquid chromatography-tandem mass spectrometry

Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, v.41 no.5, 2018년, pp.530 - 543  

Truong, Quoc-Ky (College of Pharmacy, Kangwon National University) ,  Mai, Xuan-Lan (College of Pharmacy, Kangwon National University) ,  Lee, Jae-Yong (College of Pharmacy, Kangwon National University) ,  Rhee, Jongsook (National Forensic Services (NFS)) ,  Vinh, Dinh (University of Medicine and Pharmacy Ho Chi Minh City) ,  Hong, Jongki (College of Pharmacy, Kyung Hee University) ,  Kim, Kyeong Ho (College of Pharmacy, Kangwon National University)

Abstract AI-Helper 아이콘AI-Helper

A simple, sensitive, and rapid assay based on hydrophilic interaction liquid chromatography (HILIC) with tandem mass spectrometry was developed and validated for the simultaneous determination of metformin and 13 other oral antihyperglycaemic drugs in human urine using metoprolol as an internal stan...

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참고문헌 (29)

  1. Alpert AJ (1990) Hydrophilic-interaction chromatography for the separation of peptides, nucleic acids and other polar compounds. J Chromatogr A 499:177-196 

  2. Bell DS (2004) Type 2 diabetes mellitus: what is the optimal treatment regimen? Am J Med 116:23-29 

  3. Chen X, Gu Q, Qiu F, Zhong D (2004) Rapid determination of metformin in human plasma by liquid chromatography-tandem mass spectrometry method. J Chromatogr B 802:377-381 

  4. Deventer K, Pozo OJ, Verstraete AG, Van Eenoo P (2014) Diluteband- shoot-liquid chromatography-mass spectrometry for urine analysis in doping control and analytical toxicology. Trends Anal Chem 55:1-13 

  5. Eyal S, Easterling TR, Carr D, Umans JG, Miodovnik M, Hankins GD, Clark SM, Risler L, Wang J, Kelly EJ, Shen DD, Hebert MF (2010) Pharmacokinetics of Metformin during Pregnancy. Drug Metab Dispos 38(5):833-840 

  6. Fachi MM, Cerqueira LB, Leonart LP, de Francisco TMG, Pontarolo R (2016) Simultaneous quantification of antidiabetic agents in human plasma by a UPLC-QToF-MS method. PLoS ONE 11(12):e0167107 

  7. Georgita C, Albu F, David V, Medvedovici A (2007) Simultaneous assay of metformin and glibenclamide in human plasma based on extraction-less sample preparation procedure and LC/(APCI)MS. J Chromatogr B 854:211-218 

  8. Hess C, Musshoff F, Madea B (2011) Simultaneous quantification and validated quantification of 11 oral hypoglycaemic drugs in plasma by electrospray ionisation liquid chromatography-mass spectrometry. Anal Bioanal Chem 400:33-41 

  9. Jagadeesh B, Bharathi DV, Pankaj C, Narayana VS, Venkateswarulu V (2013) Development and validation of highly selective and robust method for simultaneous estimation of pioglitazone, hydroxypioglitazone and metformin in human plasma by LC-MS/MS: application to a pharmacokinetic study. J Chromatogr B 930:136-145 

  10. Jemal M, Schuster A, Whigan DB (2003) Liquid chromatography/ tandem mass spectrometry methods for quantitation of mevalonic acid in human plasma and urine: method validation, demonstration of using a surrogate analyte, and demonstration of unacceptable matrix effect in spite of use of a stable isotope analog internal standard. Rapid Commun Mass Spectrom 17:1723-1734 

  11. Kong TY, Kim JH, Kim JY, In MK, Choi KH, Kim HS, Lee HS (2017) Rapid analysis of drugs of abuse and their metabolites in human urine using dilute and shoot liquid chromatography-tandem mass spectrometry. Arch Pharmacal Res 40:180-196 

  12. Koseki N, Kawashita H, Niina M, Nagae Y, Masuda N (2005) Development and validation for high selective quantitative determination of metformin in human plasma by cation exchanging with normal-phase LC/MS/MS. J Pharm Biomed Anal 36:1063-1072 

  13. Krentz AJ, Bailey CJ (2005) Oral antidiabetic agents: current role in type 2 diabetes mellitus. Drugs 65:385-411 

  14. Lebovitz HE (2004) Oral antidiabetic agents: 2004. Med Clin N Am 88:847-863 

  15. Li N, Deng Y, Qin F, Yu J, Li F (2013) Simultaneous quantification of metformin and glipizide in human plasma by high-performance liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study. Biomed Chromatogr 27:191-196 

  16. Liu A, Coleman SP (2009) Determination of metformin in human plasma using hydrophilic interaction liquid chromatography-tandem mass spectrometry. J Chromatogr B 877:3695-3700 

  17. Mallet CR, Lu Z, Mazzeo JR (2004) A study of ion suppression effects in electrospray ionization from mobile phase additives and solid-phase extracts. Rapid Commun Mass Spectrom 18:49-58 

  18. Marques MAS, Soares AdSS, Pinto OW, Barroso PTW, Pinto DP, Ferreira-Filho M, Werneck-Barroso E (2007) Simple and rapid method determination for metformin in human plasma using high performance liquid chromatography tandem mass spectrometry: application to pharmacokinetic studies. J Chromatogr B 852:308-316 

  19. Mistri HN, Jangid AG, Shrivastav PS (2007) Liquid chromatography tandem mass spectrometry method for simultaneous determination of antidiabetic drugs metformin and glyburide in human plasma. J Pharm Biomed Anal 45:97-106 

  20. Nakayama S, Hirose T, Watada H, Tanaka Y, Kawamori R (2005) Hypoglycemia following a nateglinide overdose in a suicide attempt. Diabetes Care 28:227-228 

  21. Polagani SR, Pilli NR, Gajula R, Gandu V (2013) Simultaneous determination of atorvastatin, metformin and glimepiride in human plasma by LC-MS/NS and its application to a human pharmacokinetic study. J Pharm Anal 3:9-19 

  22. Pontarolo R, Gimenez AC, Francisco TMGd, Ribeiro RP, Pontes FL, Gasparetto JC (2014) Simultaneous determination of metformin and vildagliptin in human plasma by a HILIC-MS/MS method. J Chromatogr B 965:133-141 

  23. Wang Y, Tang Y, Gu J, Fawcett JP, Bai X (2004) Rapid and sensitive liquid chromatography-tandem mass spectrometric method for the quantitation of metformin in human plasma. J Chromatogr B 808:215-219 

  24. Wark G (2009) How to look for insulin etc. Guildford Peptide Hormones Scheme, SAS Peptide Hormone Section, Royal Surrey County Hospital 

  25. Wu X, Zhu B, Lu L, Huang W, Pang D (2012) Optimization of a solid phase extraction and hydrophilic interaction liquid chromatography-tandem mass spectrometry method for the determination of metformin in dietary supplements and herbal medicines. Food Chem 133:482-488 

  26. Yang Y, Boysen RI, Hearn MTW (2009) Hydrophilic interaction chromatography coupled to electrospray mass spectrometry for the separation of peptides and protein digests. J Chromatogr A 1216:5518-5524 

  27. Zhang L, Tian Y, Zhang Z, Chen Y (2007) Simultaneous determination of metformin and rosiglitazone in human plasma by liquid chromatography/tandem mass spectrometry with electrospray ionization: application to a pharmacokinetic study. J Chromatogr B 854:91-98 

  28. Zhang X, Wang X, Vernikovskaya DI, Fokina VM, Nanovskaya TN, Hankins GD, Ahmed MS (2015) Quantitative determination of metformin, glyburide and its metabolites in plasma and urine of pregnant patients by LC-MS/MS. Biomed Chromatogr 29:560-569 

  29. Zhong GP, Bi HC, Zhou S, Chen X, Huang M (2005) Simultaneous determination of metformin and gliclazide in human plasma by liquid chromatography-tandem mass spectrometry: application to a bioequivalence study of two formulations in healthy volunteers. J Mass Spectrom 40:1462-1474 

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