[논문]과민성 대장증후군 환자를 대상으로 수행된 한약 및 침구치료의 객관적 효과와 기전 연구에 대한 문헌고찰

노현덕; 김민정; 조임학; 김소연

doi:10.15188/kjopp.2021.10.35.5.199

과민성 대장증후군 환자를 대상으로 수행된 한약 및 침구치료의 객관적 효과와 기전 연구에 대한 문헌고찰
Review on the Objective Effect and Mechanism Studies of Herbal Medicine, Acupuncture and Moxibustion Treatment for Irritable Bowel Syndrome Patients 원문보기

동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine, v.35 no.5, 2021년, pp.199 - 209

노현덕 (부산대학교 한의학전문대학원 한의학과) , 김민정 (부산대학교 한의학전문대학원 한의학과) , 조임학 (부산대학교 한의학전문대학원 한의학과) , 김소연 (부산대학교 한의학전문대학원 한의학과)

Abstract ▼ AI-Helper

The purpose of this study was to explore objective indicators(outcomes) which are used to evaluate clinical efficacy and figure out the mechanisms of herbal medicine, acupuncture and moxibustion treatment for Irritable bowel syndrome(IBS). We searched randomized controlled trials(RCTs) that mediated with herbal medicine, acupuncture and moxibustion treatment for IBS and used objective indicators for outcome from November 1, 2020 to December 31, 2020. The RCTs that were published in Korean, English and Chinese were included in this study. The selected literatures were analyzed about methods of result measurement and assessed by Cochrane's risk of bias(RoB). Total 18 RCTs were included in this study. There were lots of objective indicators for result measurement; the concentration of hormones in blood and neurotransmitters, the sensitivity of rectum, the functional assessment of central nerve and autonomic nerve system, the change of intestinal flora, the concentration of serum cytokines. Various objective indicators can be used to evaluate the clinical efficacy of with herbal medicine, acupuncture and moxibustion treatment for IBS, but due to the limitations of the quality of the included studies, systematic review and meta-analysis will be needed.

주제어

표/그림 (8)

표 Table 1. Keyword for Searching in Database
그림 Fig. 1. Literature Search Results(Flow Chart).
표 Table 2. Studies about Blood Hormones and Neurotransmitters
표 Table 3. Studies about Rectal Sensitivity
표 Table 4. Studies about Central and Autonomic Neuronal Activity
표 Table 5. Intestinal Microorganisms after Treatment.
표 Table 6. Immunological Indicators after Treatment.
그림 Fig. 2. Assessment of Risk of Bias on 18 RCT. A : RoB graph, B : RoB summary. Red: High risk of bias, Green: Low risk of bias, Yellow : Unclear risk of bias.

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