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[국내논문] Transforming Growth Factor β Inhibits MUC5AC Expression by Smad3/HDAC2 Complex Formation and NF-κB Deacetylation at K310 in NCI-H292 Cells 원문보기

Molecules and cells, v.44 no.1, 2021년, pp.38 - 49  

Lee, Su Ui (Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Kim, Mun-Ock (Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Kang, Myung-Ji (Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Oh, Eun Sol (Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Ro, Hyunju (Department of Biological Sciences, College of Bioscience and Biotechnology, Chungnam National University) ,  Lee, Ro Woon (Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Song, Yu Na (Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Jung, Sunin (Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Lee, Jae-Won (Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)) ,  Lee, Soo Yun (Immunotherapy Research Center, KRIBB) ,  Bae, Taeyeol (Immunotherapy Research Center, KRIBB) ,  Hong, Sung-Tae (Departm) ,  Kim, Tae-Don

Abstract AI-Helper 아이콘AI-Helper

Airway mucus secretion is an essential innate immune response for host protection. However, overproduction and hypersecretion of mucus, mainly composed of the gel-forming MUC5AC protein, are significant risk factors for patients with asthma and chronic obstructive pulmonary disease (COPD). The trans...

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참고문헌 (65)

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