$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

[국내논문] The regulatory role of Korean ginseng in skin cells 원문보기

Journal of ginseng research = 高麗人參學會誌, v.45 no.3, 2021년, pp.363 - 370  

You, Long (Department of Integrative Biotechnology, and Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University) ,  Cho, Jae Youl (Department of Integrative Biotechnology, and Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University)

Abstract AI-Helper 아이콘AI-Helper

As the largest organ in our body, the skin acts as a barrier against external stress and damages. There are various cell types of skin, such as keratinocytes, melanocytes, fibroblasts, and skin stem cells. Korean ginseng, which is one of the biggest distributions of ginseng worldwide, is processed i...

주제어

표/그림 (3)

참고문헌 (76)

  1. 1 Gould J. Superpowered skin Nature 563 2018 S84 S85 30464287 

  2. 2 Gravitz L. Skin Nature 563 2018 S83 30464282 

  3. 3 Hoerter J.D. Bradley P. Casillas A. Chambers D. Denholm C. Johnson K. Weiswasser B. Extrafollicular dermal melanocyte stem cells and melanoma Stem Cells Int 2012 2012 407079 22666269 

  4. 4 Ortonne J.P. Normal and abnormal skin color Ann Dermatol Venereol 139 2012 S125 S129 23522626 

  5. 5 Nilforoushzadeh M.A. Ashtiani H.R.A. Jaffary F. Jahangiri F. Nikkhah N. Mahmoudbeyk M. Fard M. Ansari Z. Zare S. Dermal fibroblast cells: biology and function in skin regeneration J Ski Stem Cell 4 2017 

  6. 6 Blanpain C. Fuchs E. Epidermal stem cells of the skin Annu Rev Cell Dev Biol 22 2006 339 373 16824012 

  7. 7 Yun T.K. Brief introduction of panax ginseng CA meyer J Korean Med Sci 16 2001 S3 11748372 

  8. 8 Kim K. Effect of ginseng and ginsenosides on melanogenesis and their mechanism of action J Ginseng Res 39 2015 1 6 25535470 

  9. 9 Liu X. Xiao Y. Hwang E. Haeng J.J. Yi T. Antiphotoaging and antimelanogenesis properties of ginsenoside C-Y, a ginsenoside Rb2 metabolite from American ginseng PDD-ginsenoside Photochem Photobiol 95 2019 1412 1423 31074886 

  10. 10 Nam J. Min J. Son M. Oh J. Kang S. Ultraviolet-and infrared-induced 11 beta-hydroxysteroid dehydrogenase type 1 activating skin photoaging is inhibited by red ginseng extract containing high concentration of ginsenoside Rg3 (S) Photodermatol Photoimmunol Photomed 33 2017 311 320 28793178 

  11. 11 Hwang E. Park S.-Y. Yin C.S. Kim H.-T. Kim Y.M. Yi T.H. Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skin J Ginseng Res 41 2017 69 77 28123324 

  12. 12 Barker J.N.W.N. Griffiths C.E.M. Nickoloff B.J. Mitra R.S. Dixit V.M. Nickoloff B.J. Keratinocytes as initiators of inflammation Lancet 337 1991 211 214 1670850 

  13. 13 Nickoloff B.J. Turka L.A. Keratinocytes: key immunocytes of the integument Am J Pathol 143 1993 325 331 8342589 

  14. 14 Johansen C. Generation and culturing of primary human keratinocytes from adult skin J Vis Exp 2017 2017 1 5 

  15. 15 Fuchs E. Raghavan S. Getting under the skin of epidermal morphogenesis Nat Rev Genet 3 2002 199 209 11972157 

  16. 16 Bos J.D. Kapsenberg M.L. The skin immune system its cellular constituents and their interactions Immunol Today 7 1986 235 240 25290406 

  17. 17 Nestle F.O. Di Meglio P. Qin J.Z. Nickoloff B.J. Skin immune sentinels in health and disease Nat Rev Immunol 9 2009 679 691 19763149 

  18. 18 Kim H Do Ha S.E. Kang J.R. Park J.K. Effect of Korean red ginseng extract on cell death responses in peroxynitrite-treated keratinocytes J Ginseng Res 34 2010 205 211 

  19. 19 Hillery M. Schwartz R.J. Time-averaged properties of the Jaynes-Cummings model: effects of detuning Phys Rev A 43 1991 1506 1511 9905179 

  20. 20 Cummings M.M. Cummings Martin M. Interview by ole K. Harlem Tidsskr Den Nor Laegeforening 107 1987 1151 1153 

  21. 21 Buek V. Jaynes-Cummings model with intensity-dependent coupling interacting with Holstein-Primakoff SU(1,1) coherent state Phys Rev A 39 1989 3196 3199 

  22. 22 Shumovsky A.S. Kien F Le Aliskenderov E.I. Squeezing in the multiphoton Jaynes-Cummings model Phys Lett A 124 1987 351 354 

  23. 23 Chang J.W. Park K.H. Hwang H.S. Shin Y.S. Oh Y.T. Kim C.H. Protective effects of Korean red ginseng against radiation-induced apoptosis in human HaCaT keratinocytes J Radiat Res 55 2014 245 256 24078877 

  24. 24 Kim W.Y. Kim J.M. Han S.B. Lee S.K. Kim N.D. Park M.K. Kim C.K. Park J.H. Steaming of ginseng at high temperature enhances biological activity J Nat Prod 63 2000 1702 1704 11141123 

  25. 25 Lee H. Lee J.Y. Song K.C. Kim J. Park J.H. Chun K.H. Hwang G.S. Protective effect of processed Panax ginseng, sun ginseng on UVB-irradiated human skin keratinocyte and human dermal fibroblast J Ginseng Res 36 2012 68 77 23717106 

  26. 26 Homey B. Steinhoff M. Ruzicka T. Leung D.Y.M. Cytokines and chemokines orchestrate atopic skin inflammation J Allergy Clin Immunol 118 2006 178 189 16815153 

  27. 27 Moreno A.S. Mcphee R. Arruda L.K. Howell M.D. Targeting the T helper 2 inflammatory axis in atopic dermatitis Int Arch Allergy Immunol 171 2016 71 80 27846627 

  28. 28 Böhm I. Bauer R. Th1-Zellen, Th2-Zellen und atopische Dermatitis Hautarzt 48 1997 223 227 9206708 

  29. 29 Giustizieri M.L. Mascia F. Frezzolini A. De Pità O. Chinni L.M. Giannetti A. Girolomoni G. Pastore S. Keratinocytes from patients with atopic dermatitis and psoriasis show a distinct chemokine production profile in response to T cell-derived cytokines J Allergy Clin Immunol 107 2001 871 877 11344355 

  30. 30 Hong C.-E. Lyu S.-Y. Anti-inflammatory and anti-oxidative effects of Korean red ginseng extract in human keratinocytes Immune Netw 11 2011 42 21494373 

  31. 31 Park J.H. Ahn E.K. Ko H.J. Lee J.Y. Hwang S.M. Ko S.M. Oh J.S. Korean red ginseng water extract alleviates atopic dermatitis-like inflammatory responses by negative regulation of mitogen-activated protein kinase signaling pathway in vivo Biomed Pharmacother 117 2019 109066 

  32. 32 Oh Y. Lim H.W. Kim K. Lim C.J. Ginsenoside Re improves skin barrier function in HaCaT keratinocytes under normal growth conditions Biosci Biotechnol Biochem 80 2016 2165 2167 27405604 

  33. 33 Ahn S. Siddiqi M.H. Aceituno V.C. Simu S.Y. Zhang J. Jimenez Perez Z.E. Kim Y.-J. Yang D.-C. Ginsenoside Rg5:Rk1 attenuates TNF-α/IFN-γ-induced production of thymus- and activation-regulated chemokine (TARC/CCL17) and LPS-induced NO production via downregulation of NF-κB/p38 MAPK/STAT1 signaling in human keratinocytes and macrophages Vitr Cell Dev Biol - Anim 52 2016 287 295 

  34. 34 Chung I. Lee J. Park Y.S. Lim Y. Chang D.H. Park J. Hwang J.S. Inhibitory mechanism of Korean red ginseng on GM-CSF expression in UVB-irradiated keratinocytes J Ginseng Res 39 2015 322 330 26869824 

  35. 35 Park Y.S. Lee J.E. Park J Il Myung C hwan Lim Y.H. Park C.K. Hwang J.S. Inhibitory mechanism of ginsenoside Rh3 on granulocyte–macrophage colony-stimulating factor expression in UV-B–irradiated murine SP-1 keratinocytes J Ginseng Res 44 2020 274 281 32148409 

  36. 36 Aitken G.R. Henderson J.R. Chang S.C. McNeil C.J. Birch-Machin M.A. Direct monitoring of UV-induced free radical generation in HaCaT keratinocytes Clin Exp Dermatol 32 2007 722 727 17953641 

  37. 37 Kim M.S. Oh G.H. Kim M.J. Hwang J.K. Fucosterol inhibits matrix metalloproteinase expression and promotes type-1 procollagen production in UVB-induced HaCaT cells Photochem Photobiol 89 2013 911 918 23418792 

  38. 38 Chae S. Piao M.J. Kang K.A. Zhang R. Kim K.C. Youn U.J. Nam K.-W. Lee J.H. Hyun J.W. Inhibition of matrix metalloproteinase-1 induced by oxidative stress in human keratinocytes by mangiferin isolated from Anemarrhena asphodeloides Biosci Biotechnol Biochem 75 2011 2321 2325 22146720 

  39. 39 Oh S.J. Oh Y. Ryu I.W. Kim K. Lim C.J. Protective properties of ginsenoside Rb3 against UV-B radiation-induced oxidative stress in HaCaT keratinocytes Biosci Biotechnol Biochem 80 2016 95 103 26287932 

  40. 40 Kim S. Kang B.Y. Cho S.Y. Sung D.S. Chang H.K. Yeom M.H. Kim D.H. Sim Y.C. Lee Y.S. Compound K induces expression of hyaluronan synthase 2 gene in transformed human keratinocytes and increases hyaluronan in hairless mouse skin Biochem Biophys Res Commun 316 2004 348 355 15020224 

  41. 41 Cichorek M. Wachulska M. Stasiewicz A. Tymińska A. Skin melanocytes: biology and development Postep Dermatologii I Alergol 30 2013 30 41 

  42. 42 Seiji M. Fitzpatrick T.B. The reciprocal relationship between melanization and tyrosinase activity in melanosomes (melanin granules) J Biochem 49 1961 700 706 13749805 

  43. 43 Simon J.D. Peles D. Wakamatsu K. Ito S. Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function Pigment Cell Melanoma Res 22 2009 563 579 19627559 

  44. 44 Riley P.A. Melanin. Int J Biochem Cell Biol 29 1997 1235 1239 9451820 

  45. 45 Costin G.-E. Hearing V.J. Human skin pigmentation: melanocytes modulate skin color in response to stress FASEB J 21 2007 976 994 17242160 

  46. 46 Lee A.-Y. Noh M. The regulation of epidermal melanogenesis via cAMP and/or PKC signaling pathways: insights for the development of hypopigmenting agents Arch Pharm Res 36 2013 792 801 23604723 

  47. 47 Kong Y.H. Jo Y.O. Cho C.-W. Son D. Park S. Rho J. Choi S.Y. Inhibitory effects of cinnamic acid on melanin biosynthesis in skin Biol Pharm Bull 31 2008 946 948 18451524 

  48. 48 Song M. Mun J.H. Ko H.C. Kim B.S. Kim M.B. Korean red ginseng powder in the treatment of melasma: an uncontrolled observational study J Ginseng Res 35 2011 170175 

  49. 49 Jiang R. Xu X.-H. Wang K. Yang X.-Z. Bi Y.-F. Yan Y. Liu J.-Z. Chen X.-N. Wang Z.-Z. Guo X.-L. Ethyl acetate extract from Panax ginseng C.A. Meyer and its main constituents inhibit alpha-melanocyte-stimulating hormone-induced melanogenesis by suppressing oxidative stress in B16 mouse melanoma cells J Ethnopharmacol 208 2017 149 156 28689798 

  50. 50 Lee J.-O. Kim E. Kim J.H. Hong Y.H. Kim H.G. Jeong D. Kim J. Kim S.H. Park C. Seo D.B. Antimelanogenesis and skin-protective activities of Panax ginseng calyx ethanol extract J Ginseng Res 42 2018 389 399 29983620 

  51. 51 Saba E. Kim S.-H. Lee Y.Y. Park C.-K. Oh J.-W. Kim T.-H. Kim H.-K. Roh S.-S. Rhee M.H. Korean Red Ginseng extract ameliorates melanogenesis in humans and induces antiphotoaging effects in ultraviolet B–irradiated hairless mice J Ginseng Res 2019 

  52. 52 Oh C.T. Park J Il Jung Y.R. Joo Y.A. Shin D.H. Cho H.J. Ahn S.M. Lim Y.H. Park C.K. Hwang J.S. Inhibitory effect of Korean Red Ginseng on melanocyte proliferation and its possible implication in GM-CSF mediated signaling J Ginseng Res 37 2013 389 400 24235857 

  53. 53 Jeong Y.-M. Oh W.K. Tran T.L. Kim W.-K. Sung S.H. Bae K. Lee S. Sung J.H. Aglycone of Rh4 inhibits melanin synthesis in B16 melanoma cells: possible involvement of the protein kinase A pathway Biosci Biotechnol Biochem 77 2013 119 125 23291754 

  54. 54 Lee D.Y. Jeong Y.T. Jeong S.C. Lee M.K. Min J.W. Lee J.W. Kim G.S. Lee S.E. Ahn Y.S. Kang H.C. Melanin biosynthesis inhibition effects of ginsenoside Rb2 isolated from panax ginseng berry J Microbiol Biotechnol 25 2015 2011 2015 26437949 

  55. 55 Wang L. Lu A.-P. Yu Z.-L. Wong R.N.S. Bian Z.-X. Kwok H.-H. Yue P.Y.K. Zhou L.M. Chen H. Xu M. The melanogenesis-inhibitory effect and the percutaneous formulation of ginsenoside Rb1 AAPS PharmSciTech 15 2014 1252 1262 24895076 

  56. 56 Lee S.J. Lee W.J. Chang S.E. Lee G.-Y. Antimelanogenic effect of ginsenoside Rg3 through extracellular signal-regulated kinase-mediated inhibition of microphthalmia-associated transcription factor J Ginseng Res 39 2015 238 242 26199555 

  57. 57 Kim J.H. Baek E.J. Lee E.J. Yeom M.H. Park J.S. Lee K.W. Kang N.J. Ginsenoside F1 attenuates hyperpigmentation in B16F10 melanoma cells by inducing dendrite retraction and activating Rho signalling Exp Dermatol 24 2015 150 152 25381719 

  58. 58 Imokawa G. Autocrine and paracrine regulation of melanocytes in human skin and in pigmentary disorders Pigment Cell Res 17 2004 96 110 15016298 

  59. 59 Yoshida A. Anand-Apte B. Zetter B.R. Differential endothelial migration and proliferation to basic fibroblast growth factor and vascular endothelial growth factor Growth Factors 13 1996 57 64 8962720 

  60. 60 Hirobe T. Shinpo T. Higuchi K. Sano T. Life cycle of human melanocytes is regulated by endothelin-1 and stem cell factor in synergy with cyclic AMP and basic fibroblast growth factor J Dermatol Sci 57 2010 123 131 20045284 

  61. 61 Lee J.E. Park J Il Myung C.H. Hwang J.S. Inhibitory effects of ginsenosides on basic fibroblast growth factor-induced melanocyte proliferation J Ginseng Res 41 2017 268 276 28701866 

  62. 62 Kim Y.G. Sumiyoshi M. Sakanaka M. Kimura Y. Effects of ginseng saponins isolated from red ginseng on ultraviolet B-induced skin aging in hairless mice Eur J Pharmacol 602 2009 148 156 19041641 

  63. 63 Hwang Y.P. Choi J.H. Kim H.G. Choi J.M. Hwang S.K. Chung Y.C. Jeong H.G. Cultivated ginseng suppresses ultraviolet B-induced collagenase activation via mitogen-activated protein kinases and nuclear factor κB/activator protein-1-dependent signaling in human dermal fibroblasts Nutr Res 32 2012 428 438 22749179 

  64. 64 Hossen M.J. Hong Y.D. Baek K.S. Yoo S. Hong Y.H. Kim J.H. Lee J.O. Kim D. Park J. Cho J.Y. In vitro antioxidative and anti-inflammatory effects of the compound K-rich fraction BIOGF1K, prepared from Panax ginseng J Ginseng Res 41 2017 43 51 28123321 

  65. 65 Hong Y.H. Kim D. Nam G. Yoo S. Han S.Y. Jeong S.G. Kim E. Jeong D. Yoon K. Kim S. Photoaging protective effects of BIOGF1K, a compound-K-rich fraction prepared from Panax ginseng J Ginseng Res 42 2018 81 89 29348726 

  66. 66 Liu X.-Y. Hwang E. Park B. Ngo H.T.T. Xiao Y.-K. Yi T.-H. Ginsenoside C-mx isolated from notoginseng stem-leaf ginsenosides attenuates ultraviolet B-mediated photoaging in human dermal fibroblasts Photochem Photobiol 94 2018 1040 1048 29779217 

  67. 67 Hwang E. Lee T.H. Park S.-Y. Yi T.H. Kim S.Y. Enzyme-modified Panax ginseng inhibits UVB-induced skin aging through the regulation of procollagen type I and MMP-1 expression Food Funct 5 2014 265 274 24281186 

  68. 68 Song K.C. Chang T.-S. Lee H. Kim J. Park J.H. Hwang G.S. Processed Panax ginseng, sun ginseng increases type I collagen by regulating MMP-1 and TIMP-1 expression in human dermal fibroblasts J Ginseng Res 36 2012 61 23717105 

  69. 69 Lee J. Jung E. Lee J. Huh S. Kim J. Park M. Park M. So J. Ham Y. Jung K. Hyun C.G. Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling J Ethnopharmacol 109 2007 29 34 16890388 

  70. 70 Kim W.K. Song S.Y. Oh W.K. Kaewsuwan S. Tran T.L. Kim W.S. Sung J.H. Wound-healing effect of ginsenoside Rd from leaves of Panax ginseng via cyclic AMP-dependent protein kinase pathway Eur J Pharmacol 702 2013 285 293 23399764 

  71. 71 Lee G.Y. Park K.G. Namgoong S. Han S.K. Jeong S.H. Dhong E.S. Kim W.K. Effects of Panax ginseng extract on human dermal fibroblast proliferation and collagen synthesis Int Wound J 13 2016 42 46 26507878 

  72. 72 Park S. Ko E. Lee J.H. Song Y. Cui C.-H. Hou J. Jeon B.M. Kim H.S. Kim S.C. Gypenoside LXXV promotes cutaneous wound healing in vivo by enhancing connective tissue growth factor levels via the glucocorticoid receptor pathway Molecules 24 2019 

  73. 73 Lee R. Lee N.-E. Hwang H. Rhim H. Cho I.-H. Nah S.-Y. Ginseng gintonin enhances hyaluronic acid and collagen release from human dermal fibroblasts through lysophosphatidic acid receptor interaction Molecules 24 2019 

  74. 74 Driskell R.R. Clavel C. Rendl M. Watt F.M. Hair follicle dermal papilla cells at a glance J Cell Sci 124 2011 1179 1182 21444748 

  75. 75 Park S. Shin W.S. Ho J. Fructus panax ginseng extract promotes hair regeneration in C57BL/6 mice J Ethnopharmacol 138 2011 340 344 21959181 

  76. 76 Baeg I.H. So S.H. The world ginseng market and the ginseng (Korea) J Ginseng Res 37 2013 1 7 23717152 

LOADING...
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로