[논문]Casodex/Nolvadex와 한방치료를 병행하여 호전된 재발성 침샘관암 환자 1례

양정민; 장권준; 고은비; 이지윤; 윤민지; 조온유; 정성헌; 문향란; 신광순; 황우석

doi:10.22246/jikm.2021.42.5.1062

Casodex/Nolvadex와 한방치료를 병행하여 호전된 재발성 침샘관암 환자 1례
A Case Report on Recurrent Salivary Duct Carcinoma Treated with Casodex/Nolvadex and Traditional Korean Medicine 원문보기

대한한방내과학회지 = The journal of internal Korean medicine, v.42 no.5, 2021년, pp.1062 - 1073

양정민 (장덕한방병원) , 장권준 (장덕한방병원) , 고은비 (장덕한방병원) , 이지윤 (장덕한방병원) , 윤민지 (장덕한방병원) , 조온유 (장덕한방병원) , 정성헌 (장덕한방병원) , 문향란 (장덕한방병원) , 신광순 (장덕한방병원) , 황우석 (장덕한방병원)

Abstract ▼ AI-Helper

Objectives: This study examined the case of a patient with recurrent salivary duct carcinoma and hepatic metastasis. Methods: The patient was treated with Casodex/Nolvadex from January 25th 2021 onward with doses of bicalutamide (150 mg/day) and tamoxifen (10 mg/day) every four weeks. Simultaneously, the patient was treated with Korean medicine. The tumor size was measured using computed tomography (CT). Adverse events were evaluated according to the National Cancer Institute's Common Terminology Criteria for Adverse Events (NCI-CTCAE), version 5.0. Results: Following the four-month treatment, the extent of the proximal portion of hepatic metastasis decreased, and discomfort and physical activity gradually improved. Conclusions: The results suggest that combined chemotherapy and Korean medicine may help to reduce tumor size and improve quality of life.

주제어

표/그림 (8)

표 Table 1. Prescription of Hangam-dan
표 Table 2. Prescription of Hyangsayangyi-tang
표 Table 3. Prescription of Sibjeondaebo-tang
그림 Fig. 1. Comparison of computed tomography (CT) images before and after treatment. A (2021/01/14) : 1. slightly increased size of hepatic metastasis in S4 (2.9 cm → 3.1 cm) 2. otherwise, no measurable lesion in the abdomen. B (2021/03/11) : 1. slightly decreased size of hepatic metastasis in S4 (3.1 cm → 2.8 cm) 2. otherwise, no measurable lesion in the abdomen. C (2021/05/06) : 1. slightly decreased size of hepatic metastasis in S4 (2.8 cm → 2.4 cm) 2. otherwise, no measurable lesion in the abdomen.
그림 Fig. 2. Dyspepsia progress : symptom intensity and number of repetitions was measured. *NRS : numeric rating scale
그림 Fig. 3. Arthralgia progress : symptom intensity was measured by numeric rating scale. *NRS : numeric rating scale
표 Table 4. Laboratory Findings
그림 Fig. 4. Facial palsy and ECOG : symptom intensity was measured by numeric rating scale. *NRS : numeric rating scale. **ECOG : Eastern cooperative oncology group

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