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[국내논문] Bacterial endophytes from ginseng and their biotechnological application 원문보기

Journal of ginseng research = 高麗人參學會誌, v.46 no.1, 2022년, pp.1 - 10  

Chu, Luan Luong (Faculty of Biotechnology, Chemistry and Environmental Engineering, Phenikaa University) ,  Bae, Hanhong (Department of Biotechnology, Yeungnam University)

Abstract AI-Helper 아이콘AI-Helper

Ginseng has been well-known as a medicinal plant for thousands of years. Bacterial endophytes ubiquitously colonize the inside tissues of ginseng without any disease symptoms. The identification of bacterial endophytes is conducted through either the internal transcribed spacer region combined with ...

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표/그림 (4)

참고문헌 (103)

  1. 1 Li C.P. Li R.C. An introductory note to ginseng Am J Chin Med (Gard City N Y). 1 1973 249 261 4359507 

  2. 2 Boopathi V. Subramaniyam S. Mathiyalagan R. Yang D.C. Till 2018: a survey of biomolecular sequences in genus Panax J Ginseng Res 44 1 2020 33 43 32095095 

  3. 3 Kim D.H. Chemical diversity of Panax ginseng, Panax quinquifolium , and Panax notoginseng J Ginseng Res 36 1 2012 1 15 23717099 

  4. 4 Lee S.M. Bae B.S. Park H.W. Ahn N.G. Cho B.G. Cho Y.L. Characterization of Korean red ginseng ( Panax ginseng Meyer): history, preparation method, and chemical composition J Ginseng Res 39 4 2015 384 391 26869832 

  5. 5 Yang W. Qiao X. Li K. Fan J. Bo T. Guo D.A. Identification and differentiation of Panax ginseng, Panax quinquefolium , and Panax notoginseng by monitoring multiple diagnostic chemical markers Acta Pharm Sin B 6 6 2016 568 575 27818924 

  6. 6 Kim K. Nguyen V.B. Dong J. Wang Y. Park J.Y. Lee C.L. Evolution of the Araliaceae family inferred from complete chloroplast genomes and 45S nrDNAs of 10 Panax -related species Sci Rep 7 2017 4917 28687778 

  7. 7 Baeg I.H. So S.H. The world ginseng market and the ginseng (Korea) J Ginseng Res 37 1 2013 1 7 23717152 

  8. 8 Riaz M. Rahman N.U. Zia-Ul-Haq M. Jaffar H.Z.E. Manea R. Ginseng: a dietary supplement as immune-modulator in various diseases Trends Food Sci Technol 83 2019 12 30 

  9. 9 Future Market Insights Ginseng market: 2019 analysis and review citrus flavours market by source-wild and cultivated for 2019-2027 [Internet] 2020 Feb 27 https://www.futuremarketinsights.com/reports/ginseng-market 

  10. 10 Proctor J.T. Sullivan A.J. Rupasinghe V.P. Jackson C.J. Morphological and ginsenoside differences among North American ginseng leaves J Ginseng Res 35 2 2011 155 161 23717057 

  11. 11 Kim Y.J. Zhang D. Yang D.C. Biosynthesis and biotechnological production of ginsenosides Biotechnol Adv 33 6 Pt 1 2015 717 735 25747290 

  12. 12 Cho C.W. Kim Y.C. Kang J.H. Rhee Y.K. Choi S.Y. Kim K.T. Characteristic study on the chemical components of Korean curved ginseng products J Ginseng Res 37 3 2013 349 354 24198661 

  13. 13 Shin B.K. Kwon S.W. Park J.H. Chemical diversity of ginseng saponins from Panax ginseng J Ginseng Res 39 4 2015 287 298 26869820 

  14. 14 Chu L.L. Montecillo J. Bae H. Recent advances in the metabolic engineering of yeasts for ginsenoside biosynthesis Front Bioeng Biotechnol 8 2020 139 32158753 

  15. 15 Biswas T. Mathur A.K. Mathur A. A literature update elucidating production of Panax ginsenosides with a special focus on strategies enriching the anti-neoplastic minor ginsenosides in ginseng preparations Appl Microbiol Biotechnol 101 10 2017 4009 4032 28411325 

  16. 16 Ratan Z.A. Haidere M.F. Hong Y.H. Park S.H. Lee J.O. Lee J.S. Pharmacological potential of ginseng and its major component ginsenosides J Ginseng Res 2020 10.1016/j.jgr.2020.02.004 

  17. 17 Kang S. Min H. Ginseng, the ’Immunity Boost’: the effects of Panax ginseng on immune system J Ginseng Res 36 4 2012 354 368 23717137 

  18. 18 Bai L. Gao J. Wei F. Zhao J. Wang D. Wei J. Therapeutic potential of ginsenosides as an adjuvant treatment for diabetes Front Pharmacol 9 2018 423 29765322 

  19. 19 Kim J.H. Pharmacological and medical applications of Panax ginseng and ginsenosides: a review for use in cardiovascular diseases J Ginseng Res 42 3 2018 264 269 29983607 

  20. 20 Ong W.Y. Farooqui T. Koh H.L. Farooqui A.A. Ling E.A. Protective effects of ginseng on neurological disorders Front Aging Neurosci 7 2015 129 26236231 

  21. 21 Wang L. Yang X. Yu X. Yao Y. Ren G. Evaluation of antibacterial and anti-inflammatory activities of less polar ginsenosides produced from polar ginsenosides by heat-transformation J Agric Food Chem 61 50 2013 12274 12282 24289140 

  22. 22 Dong W. Farooqui A. Leon A.J. Kelvin D.J. Inhibition of influenza A virus infection by ginsenosides PLoS One 12 2 2017 e0171936 

  23. 23 Leung K.W. Wong A.S. Ginseng and male reproductive function Spermatogenesis 3 3 2013 e26391 

  24. 24 Chen J. Du B. Cai W. Xu B. Ginsenosides and amino acids in flavored ginseng chips as affected by food formulation and processing technology Lwt-Food Sci Technol 62 1 2015 517 524 

  25. 25 Kim E. Kim D. Yoo S. Hong Y.H. Han S.Y. Jeong S. The skin protective effects of compound K, a metabolite of ginsenoside Rb1 from Panax ginseng J Ginseng Res 42 2 2018 218224 

  26. 26 Ryan R.P. Germaine K. Franks A. Ryan D.J. Dowling D.N. Bacterial endophytes: recent developments and applications FEMS Microbiol Lett 278 1 2008 1 9 18034833 

  27. 27 Kusari S. Hertweck C. Spiteller M. Chemical ecology of endophytic fungi: origins of secondary metabolites Chem Biol 19 7 2012 792 798 22840767 

  28. 28 Golinska P. Wypij M. Agarkar G. Rathod D. Dahm H. Rai M. Endophytic actinobacteria of medicinal plants: diversity and bioactivity Antonie Van Leeuwenhoek 108 2 2015 267 289 26093915 

  29. 29 Nalini M.S. Prakash H.S. Diversity and bioprospecting of actinomycete endophytes from the medicinal plants Lett Appl Microbiol 64 4 2017 261 270 28107573 

  30. 30 Atanasov A.G. Waltenberger B. Pferschy-Wenzig E.M. Linder T. Wawrosch C. Uhrin P. Discovery and resupply of pharmacologically active plant-derived natural products: a review Biotechnol Adv 33 8 2015 1582 1614 26281720 

  31. 31 Gouda S. Das G. Sen S.K. Shin H.S. Patra J.K. Endophytes: a treasure house of bioactive compounds of medicinal importance Front Microbiol 7 2016 1538 27746767 

  32. 32 Hyde K.D. Bussaban B. Paulus B. Crous P.W. Lee S. Mckenzie E.H.C. Diversity of saprobic microfungi Biodivers Conserv 16 2007 7 35 

  33. 33 Park Y.H. Kim Y. Mishra R.C. Bae H. Fungal endophytes inhabiting mountain-cultivated ginseng ( Panax ginseng Meyer): diversity and biocontrol activity against ginseng pathogens Sci Rep 7 1 2017 16221 29176690 

  34. 34 Chowdhury M.D.E.K. Jeon J. Rim S.O. Park Y.-H. Lee S.K. Bae H. Composition, diversity and bioactivity of culturable bacterial endophytes in mountain-cultivated ginseng in Korea Sci Rep 7 1 2017 10098 28855721 

  35. 35 Cho K.M. Hong S.Y. Lee S.M. Kim Y.H. Kahng G.G. Lim Y.P. Endophytic bacterial communities in ginseng and their antifungal activity against pathogens Microb Ecol 54 2 2007 341 351 17492474 

  36. 36 Hong C.E. Kim J.U. Lee J.W. Bang K.H. Jo I.H. Metagenomic analysis of bacterial endophyte community structure and functions in Panax ginseng at different ages 3 Biotech 9 8 2019 300 

  37. 37 Guan Y. Chen M. Ma Y. Du Z. Yuan N. Li Y. Xiao J. Zhang Y. Whole-genome and time-course dual RNA-Seq analyses reveal chronic pathogenicity-related gene dynamics in the ginseng rusty root rot pathogen Ilyonectria robusta Sci Rep 10 1 2020 17122 33028879 

  38. 38 Fu Y. Yin Z.H. Yin C.Y. Biotransformation of ginsenoside Rb1 to ginsenoside Rg3 by endophytic bacterium Burkholderia sp. GE 17-7 isolated from Panax ginseng J Appl Microbiol 122 6 2017 1579 1585 28256039 

  39. 39 Fu Y. Biotransformation of ginsenoside Rb1 to Gyp-XVII and minor ginsenoside Rg3 by endophytic bacterium Flavobacterium sp. GE 32 isolated from Panax ginseng Lett Appl Microbiol 68 2 2019 134 141 30362617 

  40. 40 Fu Y. Yin Z.H. Wu L.P. Yin C.R. Biotransformation of ginsenoside Rb1 to ginsenoside C-K by endophytic fungus Arthrinium sp. GE 17-18 isolated from Panax ginseng Lett Appl Microbiol 63 3 2016 196 201 27316666 

  41. 41 Shi J. Zeng Q. Liu Y. Pan Z. Alternaria sp. MG1, a resveratrol-producing fungus: isolation, identification, and optimal cultivation conditions for resveratrol production Appl Microbiol Biotechnol 95 2 2012 369 379 22526800 

  42. 42 Park Y.H. Mishra R.C. Yoon S. Kim H. Park C. Seo S.T. Endophytic Trichoderma citrinoviride isolated from mountain-cultivated ginseng ( Panax ginseng ) has great potential as a biocontrol agent against ginseng pathogens J Ginseng Res 43 3 2019 408 420 31308813 

  43. 43 Subramanian M. Marudhamuthu M. Hitherto unknown terpene synthase organization in Taxol-producing endophytic bacteria isolated from marine macroalgae Curr Microbiol 77 6 2020 918 923 31970484 

  44. 44 Ma L. Cao Y.H. Cheng M.H. Huang Y. Mo M.H. Wang Y. Phylogenetic diversity of bacterial endophytes of Panax notoginseng with antagonistic characteristics towards pathogens of root-rot disease complex Antonie Van Leeuwenhoek 103 2 2013 299-312 22987248 

  45. 45 Dong L. Cheng R. Xiao L. Wei F. Wei G. Xu J. Diversity and composition of bacterial endophytes among plant parts of Panax notoginseng Chin Med 13 2018 41 2018 30127840 

  46. 46 Eevers N. Gielen M. Sanchez-Lopez A. Jaspers S. White J.C. Vangronsveld J. Optimization of isolation and cultivation of bacterial endophytes through addition of plant extract to nutrient media Microb Biotechnol 8 4 2015 707-15 25997013 

  47. 47 Song X. Wu H. Yin Z. Lian M. Yin C. Endophytic bacteria isolated from Panax ginseng improves ginsenoside accumulation in adventitious ginseng root culture Molecules 22 6 2017 837 

  48. 48 Singh D. Sharma A. Saini G.K. Biochemical and molecular characterisation of the bacterial endophytes from native sugarcane varieties of Himalayan region 3 Biotech 3 3 2013 205-12 

  49. 49 Tam N.T. Tam N.P. Nguyen V.T.H. Hung N.K. Huy C.N. Ngoc P.B. Isolation and screening of endophytic bacteria from Ngoc Linh ginseng ( Panax vietnamensis Ha et Grushv) for biosynthesis β-glucosidase J Bio 40 2 2018 154 162 15625/0866-7160/v40n2.10862 

  50. 50 Poretsky R. Rodriguez -R.L.M. Luo C. Tsementzi D. Konstantinidis K.T. Strengths and limitations of 16S rRNA gene amplicon sequencing in revealing temporal microbial community dynamics PLoS One 9 4 2014 e93827 

  51. 51 Liu S. Li D. Cui X. Chen L. Nian H. Community analysis of endophytic bacteria from the seeds of the medicinal plant Panax notoginseng J Agric Sci 9 1 2017 

  52. 52 Fadiji A.E. Babalola O.O. Elucidating mechanisms of endophytes used in plant protection and other bioactivities with multifunctional prospects Front Bioeng Biotechnol 8 2020 467 32500068 

  53. 53 Kim H. Mohanta T.K. Park Y.H. Park S.C. Shanmugam G. Park J.S. Complete genome sequence of the mountain-cultivated ginseng endophyte Burkholderia stabilis and its antimicrobial compounds against ginseng root rot disease Biol Control 140 2020 104126 

  54. 54 Tan Y. Cui Y. Li H. Kuang A. Li X. Wei Y. Diversity and composition of rhizospheric soil and root endogenous bacteria in Panax notoginseng during continuous cropping practices J Basic Microbiol 57 4 2017 337 344 28060404 

  55. 55 Liu X. Zhao Z. Li S. Zhang L. Tian Y. Sun F. The community structure and diversity of the endophytes in American ginseng Wei Sheng Wu Xue Bao 55 3 2015 330 340 26065275 

  56. 56 Hong C.E. Kim J.U. Lee J.W. Lee S.W. Jo I.H. Diversity of bacterial endophytes in Panax ginseng and their protective effects against pathogens 3 Biotech 8 9 2018 397 

  57. 57 Chi F. Shen S.H. Cheng H.P. Jing Y.X. Yanni Y.G. Dazzo F.B. Ascending migration of endophytic rhizobia, from roots to leaves, inside rice plants and assessment of benefits to rice growth physiology Appl Environ Microbiol 71 11 2005 7271 7278 16269768 

  58. 58 Park Y.H. Lee S.G. Ahn D.J. Kwon T.R. Park S.U. Lim H.S. Diversity of fungal endophytes in various tissues of Panax ginseng Meyer cultivated in Korea J Ginseng Res 36 2 2012 211 217 23717122 

  59. 59 Vendan R.T. Yu Y.J. Lee S.H. Rhee Y.H. Diversity of endophytic bacteria in ginseng and their potential for plant growth promotion J Microbiol 48 5 2010 559 565 21046332 

  60. 60 Zhang H. Abid S. Ahn J.C. Mathiyalagan R. Kim Y.J. Yang D.C. Wang Y. Characteristics of Panax ginseng cultivars in Korea and China Molecules 25 11 2020 2635 

  61. 61 Wang S. Ren X. Huang B. Wang G. Zhou P. An Y. Aluminium-induced reduction of plant growth in alfalfa ( Medicago sativa ) is mediated by interrupting auxin transport and accumulation in roots Sci Rep 6 2016 30079 27435109 

  62. 62 Spaepen S. Vanderleyden J. Auxin and plant-microbe interactions Cold Spring Harb Perspect Biol 3 4 2011 a001438 21084388 

  63. 63 Um Y. Kim B.R. Jeong J.J. Chung C.M. Lee Y. Identification of endophytic bacteria in Panax ginseng seeds and their potential for plant growth promotion Korean J Med Crop Sci 22 4 2014 306 312 

  64. 64 Gao Y. Liu Q. Zang P. Li X. Ji Q. He Z. Zhao Y. Yang H. Zhao X. Zhang L. An endophytic bacterium isolated from Panax ginseng C.A. Meyer enhances growth, reduces morbidity, and stimulates ginsenoside biosynthesis Phytochem Lett 11 2015 132 138 

  65. 65 Leventhal G.E. Ackermann M. Schiessl K.T. Why microbes secrete molecules to modify their environment: the case of iron-chelating siderophores J R Soc Interface 16 150 2019 20180674 30958157 

  66. 66 Ferreira C.M.H. Vilas-Boas A. Sousa C.A. Soares H.M.V.M. Soares E.V. Comparison of five bacterial strains producing siderophores with ability to chelate iron under alkaline conditions AMB Express 9 1 2019 78 31139942 

  67. 67 Rungin S. Indananda C. Suttiviriya P. Kruasuwan W. Jaemsaeng R. Thamchaipenet A. Plant growth enhancing effects by a siderophore-producing endophytic streptomycete isolated from a Thai jasmine rice plant ( Oryza sativa L. cv. KDML105) Antonie Van Leeuwenhoek 102 3 2012 463 472 22836676 

  68. 68 Sharma S.B. Sayyed R.Z. Trivedi M.H. Gobi T.A. Phosphate solubilizing microbes: sustainable approach for managing phosphorus deficiency in agricultural soils SpringerPlus 2 2013 587 25674415 

  69. 69 Yang Z. Yang S. Van Nostrand J.D. Zhou J. Fang W. Qi Q. Microbial community and functional gene changes in arctic tundra soils in a microcosm warming experiment Front Microbiol 8 2017 1741 28974946 

  70. 70 Wang J. Li R. Zhang H. Wei G. Li Z. Beneficial bacteria activate nutrients and promote wheat growth under conditions of reduced fertilizer application BMC Microbiol 20 1 2020 38 32085752 

  71. 71 Suzuki I. Horie N. Sugiyama T. Omata T. Identification and characterization of two nitrogen-regulated genes of the cyanobacterium Synechococcus sp. strain PCC7942 required for maximum efficiency of nitrogen assimilation J Bacteriol 177 2 1995 290-6 7814317 

  72. 72 Herrero A. Muro-Pastor A.M. Flores E. Nitrogen control in cyanobacteria J Bacteriol 183 2 2001 411-25 11133933 

  73. 73 Yurgel S.N. Rice J. Mulder M. Kahn M.L. GlnB/GlnK PII proteins and regulation of the Sinorhizobium meliloti Rm1021 nitrogen stress response and symbiotic function J Bacteriol 192 10 2010 2473 2481 20304991 

  74. 74 Ek-Ramos M.J. Gomez-Flores R. Orozco-Flores A.A. Rodriguez-Padilla C. Gonzalez-Ochoa G. Tamez-Guerra P. Bioactive products from plant-endophytic gram-positive bacteria Front. Microbiol 10 2019 463 30984118 

  75. 75 Yu H. Zhao J. You J. Li J. Ma H. Chen X. Factors influencing cultivated ginseng ( Panax ginseng C. A. Meyer) bioactive compounds PLoS One 14 10 2019 e0223763 

  76. 76 Fischer D. Gessner G. Fill T.P. Barnett R. Tron K. Dornblut K. Disruption of membrane integrity by the bacterium-derived antifungal Jagaricin Antimicrob Agents Chemother 63 9 2019 e00707 e00719 31235622 

  77. 77 Huang H. Ullah F. Zhou D.X. Yi M. Zhao Y. Mechanisms of ROS regulation of plant development and stress responses Front Plant Sci 10 2019 800 31293607 

  78. 78 Vannier N. Agler M. Hacquard S. Microbiota-mediated disease resistance in plants PLoS Pathog 15 6 2019 e1007740 

  79. 79 Cui J.L. Wang Y.N. Jiao J. Gong Y. Wang J.H. Wang M.L. Fungal endophyte-induced salidroside and tyrosol biosynthesis combined with signal cross-talk and the mechanism of enzyme gene expression in Rhodiola crenulata Sci Rep 7 1 2017 12540 28970519 

  80. 80 Scheffers D.J. Pinho M.G. Bacterial cell wall synthesis: new insights from localization studies Microbiol Mol Biol Rev 69 4 2005 585 607 16339737 

  81. 81 Verma S.C. Ladha J.K. Tripathi A.K. Evaluation of plant growth promoting and colonization ability of endophytic diazotrophs from deep water rice J Biotechnol 81 2001 127 141 

  82. 82 Suto M. Takebayashi M. Saito K. Tanaka M. Yokota A. Tomita F. Endophytes as producers of xylanase J Biosci Bioeng 93 2002 88 90 16233170 

  83. 83 Chowdhury M.D.E.K. Bae H. Bacterial endophytes isolated from mountain-cultivated ginseng ( Panax ginseng Mayer) have biocontrol potential against ginseng pathogens Biol Control 126 2018 97 108 

  84. 84 Chandler D. Bailey A.S. Tatchell G.M. Davidson G. Greaves J. Grant W.P. The development, regulation and use of biopesticides for integrated pest management Philos Trans R Soc B 366 1573 2011 1987 1998 

  85. 85 Llontop M.M.E. Hurley K. Tian L. Galeano V.A.B. Wildschutte H.K. Marine S.C. Exploring rain as source of biological control agents for fire blight on apple Front Microbiol 11 2020 199 32117187 

  86. 86 Pawar S. Chaudhari A. Prabha R. Shukla R. Singh D.P. Microbial pyrrolnitrin: natural metabolite with immense practical utility Biomolecules 9 9 2019 443 

  87. 87 Szakiel A. Paczkowski C. Henry M. Influence of environmental abiotic factors on the content of saponins in plants Phytochem Rev 10 2011 471 491 

  88. 88 Kim D.S. Song M. Kim S.H. Jang D.S. Kim J.B. Ha B.K. The improvement of ginsenoside accumulation in Panax ginseng as a result of γ-irradiation J Ginseng Res 37 3 2013 332 340 24198659 

  89. 89 Oh J.Y. Kim Y.J. Jang M.G. Joo S.C. Kwon W.S. Kim S.Y. Investigation of ginsenosides in different tissues after elicitor treatment in Panax ginseng J Ginseng Res 38 4 2014 270 277 25379007 

  90. 90 Ma R. Sun L. Chen X. Mei B. Chang G. Wang M. Proteomic analyses provide novel insights into plant growth and ginsenoside biosynthesis in forest cultivated Panax ginseng (F. Ginseng) Front Plant Sci 7 2016 1 26858731 

  91. 91 Xue L. He Z. Bi X. Xu W. Wei T. Wu S. Transcriptomic profiling reveals MEP pathway contributing to ginsenoside biosynthesis in Panax ginseng BMC Genomics 20 1 2019 383 31101014 

  92. 92 Lee H.J. Jeong J. Alves A.C. Han S.T. In G. Kim E.H. Metabolomic understanding of intrinsic physiology in Panax ginseng during whole growing seasons J Ginseng Res 43 4 2019 654 665 31700261 

  93. 93 Zhang M.M. Wang Y. Ang E.L. Zhao H. Engineering microbial hosts for production of bacterial natural products Nat Prod Rep 33 8 2016 963 987 27072804 

  94. 94 Chemat F. Vian M.A. Fabiano-Tixier A.S. Nutrizio M. Jambrak A.R. Munekata P.E. A review of sustainable and intensified techniques for extraction of food and natural products Green Chem 22 2020 2325 2353 

  95. 95 Hardoim P.R. van Overbeek L.S. Berg G. Pirttila A.M. Compant S. Campisano A. The hidden world within plants: ecological and evolutionary considerations for defining functioning of microbial endophytes Microbiol Mol Biol Rev 79 3 2015 293 320 26136581 

  96. 96 Yue J. Hu X. Sun H. Yang Y. Huang J. Widespread impact of horizontal gene transfer on plant colonization of land Nat Commun 3 2012 1152 23093189 

  97. 97 Yan H. Jin H. Fu Y. Yin Z. Yin C. Production of rare ginsenosides Rg3 and Rh2 by endophytic bacteria from Panax ginseng J Agric Food Chem 67 31 2019 8493 8499 31310523 

  98. 98 Geraldi A. Advances in the production of minor ginsenosides using microorganisms and their enzymes BIO Integration 1 1 2020 15 24 

  99. 99 Li W. Fan D. Biocatalytic strategies for the production of ginsenosides using glycosidase: current state and perspectives Appl Microbiol Biotechnol 104 2020 3807 3823 32125478 

  100. 100 Hegazy M.E. Mohamed T.A. ElShamy A.I. Mohamed A.E. Mahalel U.A. Reda E.H. Microbial biotransformation as a tool for drug development based on natural products from mevalonic acid pathway: a review J Adv Res 6 1 2015 17 33 25685541 

  101. 101 de Carvalho C.C. Whole cell biocatalysts: essential workers from nature to the industry Microb Biotechnol 10 2 2017 250 263 27145540 

  102. 102 Hug J.J. Krug D. Muller R. Bacteria as genetically programmable producers of bioactive natural products Nat Rev Chem 4 2020 172 193 

  103. 103 Yu S. Zhou X. Li F. Xu C. Zheng F. Li J. Microbial transformation of ginsenoside Rb1, Re and Rg1 and its contribution to the improved anti-inflammatory activity of ginseng Sci Rep 7 1 2017 138 28273939 

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