[논문]비약물 중재프로그램이 경도인지장애 노인의 우울 증상에 미치는 효과: 체계적 문헌고찰과 메타분석

방양희; 조미정

doi:10.17703/jcct.2022.8.5.71

비약물 중재프로그램이 경도인지장애 노인의 우울 증상에 미치는 효과: 체계적 문헌고찰과 메타분석
Effects of non-pharmacological intervention on depressive symptoms in the older adults with mild cognitive impairment : A systematic review and meta-analysis 원문보기

Journal of the convergence on culture technology : JCCT = 문화기술의 융합, v.8 no.5, 2022년, pp.71 - 80

방양희 (백석문화대학교 간호학과) , 조미정 (이화여자대학교 간호학과)

초록
AI-Helper

본 연구는 국내·외 경도인지장애 노인에게 시행된 비약물 중재의 우울 증상에 대한 효과를 확인하기 위해 시행되었다. PubMed, CINAHL, PsycINFO, Science direct, KISS, RISS, DBPia 등의 전자 데이터베이스를 통해 총1,147편의 문헌을 검색하였고 문헌선정 기준을 충족하는 21편의 문헌이 선정되었다. 선정된 문헌의 질평가는 2명의연구자가 독립적으로 시행하였다. 비약물 중재의 효과크기는 CMA3.0 프로그램을 이용하여 분석하였고, 분석결과 비약물 중재의 우울 증상에 대한 전체 효과크기는 중간효과크기(ES=-0.68)로 나타났다. 하위그룹 분석결과, 인지중재(ES=-1.03)와 복합중재(ES=-0.97)가 운동중재(ES=-0.53)에 비해 큰 효과크기를 나타냈다. 본 연구결과 비약물 중재가 경도인지장애 노인의 우울 증상 감소에 효과적임이 확인되었으며, 이를 토대로 경도인지장애 노인의 인지기능과 우울 증상 개선을 위한 다양한 비약물 중재프로그램이 시행되기를 기대한다.

Abstract ▼ AI-Helper

The purpose of this study was to evaluate the effects of the non-pharmacological intervention on depressive symptoms in the older adults with mild cognitive impairment. A total of 1,147 studies were retrieved from PubMed, CINAHL, PsycINFO, Science direct, KISS, RISS, and DBPia. Twenty-one studies which met the criteria were selected and the quality assessment was conducted independently by two investigators. The effect size of non-pharmacological intervention was estimated using Comprehensive Meta-Analysis 3.0. The overall effect size turned out to be the medium effect size (Hedges' g=-0.68, 95% CI=-1.01~-0.36). As a result of the subgroup analysis, the intervention type was statistically significant. The effect size of cognitive intervention (Hedges' g=-1.03, 95% CI=-1.43~-0.61) and multi component intervention (Hedges' g=-0.97, 95% CI=-1.63~-0.33) was greater than excise intervention (Hedges' g=-0.53, 95% CI=-1.16~0.03). This study shows that non-pharmacological intervention was also effective in reducing depressive symptoms in the older adults with mild cognitive impairment. Based on the research results, it is expected that various non-pharmacological intervention studies will be attempted to improve cognitive function and depressive symptoms of the older adults with mild cognitive impairment.

주제어

표/그림 (5)

그림 그림 1. 문헌검색과정 Figure 1. Flow diagram of study selection
그림 그림 2. RCT연구의 질평가 결과 Figure 2. Risk of bias on RCT
표 표 1. 문헌의 일반적 특성 Table 1. Characteristics of Article Analyzed in the Study
그림 그림 3. 비약물 중재 프로그램의 효과크기 Figure 3. Effect size of the non-pharmacological intervention on MCI(random effect model)
표 표 2. 비약물 중재의 조절변수에 대한 하위그룹 분석 결과 Table 2. Subgroup Analysis of Moderator Variables in Non-pharmacological Intervention

참고문헌 (30)

R.C. Petersen, G.E. Smith, S.C. Waring, R.J. Ivnik, E.G. Tangalos, and E. Kokmen. "Mild cognitive impairment:clinical characterization and outcome," Archives of Neurology, Vol. 56, No. 3, pp. 303-308, 1999. https://doi.org/10.1001/archneur.56.3.303

상세보기
National Institute of Dementia. Korean Dementia observatory 2019. https://www.nid.or.kr/info/dataroom_view.aspx?bid209
R.C. Petersen, R. Doody, A. Kurz, R.C. Mohs, J.C. Morris, P.V. Rabins, et al. "Current concepts in mild cognitive impairment," Archives of Neurology, Vol. 58, No. 12, pp. 1985-1992, 2001. https://doi.org/10.1001/archneur.58.12.1985

상세보기
C.M. Hong. "Review of dementia and mild cognitive impairment," Review of Korea Contents Association, Vol. 10, No. 2, pp. 25-30, 2012. https://doi.org/10.20924/CCTHBL.2012.10.2.025

원문보기 상세보기
S.H. Ryu. "The clinical significance of cognitive interventions for the patients with mild cognitive impairment," Journal of Korean Neuropsychiatric Association, Vol. 57, No. 1, pp. 23-29, 2018. https://doi.org/10.4306/jknpa.2018.57.1.23

상세보기
M. Huckans, L. Hutson, E. Twamley, A. Jak, J. Kaye, and D. Storzbach. "Efficacy of cognitive rehabilitation therapies for mild cognitive impairment (MCI) in older adults:working toward a theoretical model and evidence-based interventions," Neuropsychology Review, Vol. 23, No. 1, pp. 63-80, 2013. https://doi.org/10.1007/s11065-013-9230-9

상세보기
J.H. Lee, Y.M Choe, M.S. Byun, H.J. Choi, H.W. Baek, B.K. Sohn, et al. "Prevalence and associated factors of depression in mild cognitive impairment," Journal of Korean Geriatric Psychiatry, Vol. 18, No. 2, pp. 86-91, 2014. http://doi.org/10.0000/jkgp.2014.18.2.86
S.S. Mirza, M.A. Ikram, D. Bos, R. Mihaescu, A. Hofman, and H. Tiemeier. "Mild cognitive impairment and risk of depression and anxiety: a population-based study," Alzheimer's & Dementia, Vol. 13, No. 2, pp. 130-139, 2017. https://doi.org/10.1016/j.jalz.2016.06.2361

상세보기
Y.S. Shim, D.W. Yang, B. Yoon, Y. Lee, C.H. Hong, S.W. Seo, et al. "Clinical predictors for mild cognitive impairment progression in a Korean cohort," Dementia and Neurocognitive Disorders, Vol. 15, No. 3, pp. 68-74, 2016. https://doi.org/10.12779/dnd.2016.15.3.68

상세보기
F. Zheng, B. Zhong, X. Song, and W. Xie. "Persistent depressive symptoms and cognitive decline in older adults," The British Journal of Psychiatry, Vol. 213, No. 5, pp. 638-644, 2018. https://doi.org/10.1192/bjp.2018.155

상세보기
J.R. Gatchel, J.S. Rabin, R.F. Buckley, J.J. Locascio, Y.T. Quiroz, H.S. Yang, et al. "Longitudinal association of depression symptoms with cognition and cortical amyloid among community-dwelling older adults," JAMA Network Open, Vol. 2, No. 8, pp. e198964, 2019. https://doi.org/10.1001/jamanetworkopen.2019.8964

상세보기
D. Lee and S.J. Seong. "Korean national dementia plans: from 1st to 3rd," Journal of the Korean Medical Association, Vol. 61, No. 5, pp. 298-303, 2018. https://doi.org/10.5124/jkma.2018.61.5.298

상세보기
S.H. Lim. "Cognitive-based intervention for the older adults with mild cognitive impairment: a literature review," Journal of the Korea Convergence Society, Vol. 12, No. 2, pp. 327-336, 2021. https://doi.org/10.15207/JKCS.2021.12.2.327

원문보기 상세보기
K.Y. Kim and E.J. Lee. "Effect of cognitive improvement programs for mild cognitive impairment in Korean elderly: a meta-analysis," Korean Journal of Adult Nursing, Vol. 29, No. 2, pp. 177-189, 2017. https://doi.org/10.7475/kjan.2017.29.2.177

원문보기 상세보기
W. He, M. Wang, L. Jiang, M. Li, and X. Han. "Cognitive interventions for mild cognitive impairment and dementia: an overview of systematic reviews," Complementary Therapies in Medicine. Vol. 47, pp. 102199, 2019. https://doi.org/10.1016/j.ctim.2019.102199

상세보기
SJ. Oh, S. Seo, J.H. Lee, M.J. Song, and M.S. Shin. "Effects of smartphone-based memory training for older adults with subjective memory complaints: a randomized controlled trial," Aging and Mental Health, Vol. 22, No. 4, pp. 526-534, 2018. https://doi.org/10.1080/13607863.2016.1274373

상세보기
G. Savulich, T. Piercy, C. Fox, J. Suckling, J.B. Rowe, J.T. O'Brien, et al. "Cognitive training using a novel memory game on an iPad in patients with amnestic mild cognitive impairment (aMCI)," International Journal of Neuropsychopharmacology, Vol. 20, No. 8, pp. 624-633, 2017. https://doi.org/10.1093/ijnp/pyx040

상세보기
M.J. Page, J.E. McKenzie, P.M. Bossuyt, I. Boutron, T.C. Hoffmann, C.D. Mulrow, et al. "The PRISMA 2020 statement: An updated guideline for reporting systematic reviews," BMJ, Vol. 372, pp. n71, 2021. https://doi.org/10.1136/bmj.n71

상세보기
J.A. Sterne, J. Savovic, M.J. Page, R.G. Elbers, N.S. Blencowe, I. Boutron, et al. "RoB 2: a revised tool for assessing risk of bias in randomised trials," BMJ, Vol. 366, pp. 14898, 2019. https://doi.org/10.1136/bmj.l4898
National Evidence-based Healthcare Collaboration Agency. NECA's guidance for undertaking systematic reviews and meta-analyses for intervention. 1st ed, p. 270, NECA, 2011.
J. Cohen. Statistical power analysis for the behavioral sciences. 2nd ed, p. 490, Lawrence Erlbaum Associates, 1998.
E.J. Ahn and H. Kang. "Introduction to systematic review and meta-analysis," Korean Journal of Anesthesiology, Vol. 71, No. 2, pp. 103-112, 2018. https://doi.org/10.4097/kjae.2018.71.2.103

상세보기
S.H. Kim and B.K. Kim. "Effects of cognitive-based interventions of older adults with mild cognitive impairment: a systematic review and meta-analysis," Korean Journal of Adult Nursing, Vol. 30, No. 4, pp. 347-361, 2018. https://doi.org/10.7475/kjan.2018.30.4.347

상세보기
J.E. Lee. "An integrated literature review of non-pharmacological intervention in older adults with mild cognitive impairment," Journal of Digital Convergence, Vol. 19, No. 3, pp. 471-482. 2021. https://doi.org/10.14400/JDC.2021.19.3.471

원문보기 상세보기
H.S. Lee, H.H. Choi, Y.K. Yoo, and S.I. Lim. "Meta-analysis of study of the education and the effective treatment programs for the aged," Journal of Welfare for the Aged, Vol. 56, pp. 93-114, 2012.
L.S Scher, R.A. Maynard, and M. Stagner. "Interventions intended to reduce pregnancy related outcomes among adolescents," Campbell Systematic Reviews, Vol. 2, No. 1, pp. 1-70, 2006. https://doi.org/10.4073/csr.2006.12

상세보기
V. Orgeta, A. Qazi, A. Spector, and M. Orrell. "Psychological treatments for depression and anxiety in dementia and mild cognitive impairment: a systematic review and meta-analysis," The British Journal of Psychiatry, Vol. 207, No. 4, pp. 293-298, 2015. https://doi.org/10.1192/bjp.bp.114.148130

상세보기
N.T. Hill, L. Mowszowski, S.L. Naismith, V.L. Chadwick, M. Valenzuela, and A. Lampit. "Computerized cognitive training in older adults with mild cognitive impairment or dementia: a systematic review and meta-analysis," American Journal of Psychiatry, Vol. 174, No. 4, pp. 329- 340, 2017. https://doi.org/10.1176/appi.ajp.2016.16030360

상세보기
K.R. Shin, Y. Kang, M. Kim, D. Jung, and E. Lee. "Prediction of depression among elderly with mild cognitive impairment living in the community," Korean Journal of Adult Nursing, Vol. 24, No. 3, pp. 171-182, 2012. http://doi.org/10.7475/kjan.2012.24.2.171

원문보기 상세보기
M.J. Aartsen, T. Van Tilburg, C.H. Smits, K.C. Knipscheer. "A longitudinal study of the impact of physical and cognitive decline on the personal network in old age," Journal of Social and Personal Relationships, Vol. 21, No. 2, pp. 249-266, 2004. https://doi.org/10.1177/0265407504041386

상세보기

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