[논문]Receiver Operating Characteristic Analysis for Prediction of Postpartum Metabolic Diseases in Dairy Cows in an Organic Farm in Korea

Kim, Dohee; Choi, Woojae; Ro, Younghye; Hong, Leegon; Kim, Seongdae; Yoon, Ilsu; Choe, Eunhui; Kim, Danil

doi:10.17555/jvc.2022.39.5.199

Receiver Operating Characteristic Analysis for Prediction of Postpartum Metabolic Diseases in Dairy Cows in an Organic Farm in Korea 원문보기

Journal of veterinary clinics = 한국임상수의학회지, v.39 no.5, 2022년, pp.199 - 206

Kim, Dohee (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) , Choi, Woojae (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) , Ro, Younghye (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) , Hong, Leegon (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) , Kim, Seongdae (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) , Yoon, Ilsu (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University) , Choe, Eunhui (Farm Animal Clinical Training and Research Center, Institute of Green-Bio Science and Technology, Seoul National University) , Kim, Danil (College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University)

Abstract ▼ AI-Helper

Postpartum diseases should be predicted to prevent productivity loss before calving especially in organic dairy farms. This study was aimed to investigate the incidence of postpartum metabolic diseases in an organic dairy farm in Korea, to confirm the association between diseases and prepartum blood biochemical parameters, and to evaluate the accuracy of these parameters with a receiver operating characteristic (ROC) analysis for identifying vulnerable cows. Data were collected from 58 Holstein cows (16 primiparous and 42 multiparous) having calved for 2 years on an organic farm. During a transition period from 4 weeks prepartum to 4 weeks postpartum, blood biochemistry was performed through blood collection every 2 weeks with a physical examination. Thirty-one (53.4%) cows (9 primiparous and 22 multiparous) were diagnosed with at least one postpartum disease. Each incidence was 27.6% for subclinical ketosis, 22.4% for subclinical hypocalcemia, 12.1% for retained placenta, 10.3% for displaced abomasum and 5.2% for clinical ketosis. Between at least one disease and no disease, there were significant differences in the prepartum levels of parameters like body condition score (BCS), non-esterified fatty acid (NEFA), total bilirubin (T-bil), direct bilirubin (D-bil) and NEFA to total cholesterol (T-chol) ratio (p < 0.05). The ROC analysis of each of these prepartum parameters had the area under the curve (AUC) <0.7. However, the ROC analysis with logistic regression including all these parameters revealed a higher AUC (0.769), sensitivity (71.0%), and specificity (77.8%). The ROC analysis with logistic regression including the prepartum BCS, NEFA, T-bil, D-bil, and NEFA to T-chol ratio can be used to identify cows that are vulnerable to postpartum diseases with moderate accuracy.

주제어

참고문헌 (34)

Asl AN, Nazifi S, Ghasrodashti AR, Olyaee A. Prevalence of subclinical ketosis in dairy cattle in the Southwestern Iran and detection of cutoff point for NEFA and glucose concentrations for diagnosis of subclinical ketosis. Prev Vet Med 2011; 100: 38-43.

상세보기
Bell AW. Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation. J Anim Sci 1995; 73: 2804-2819.

상세보기
Caixeta LS, Omontese BO. Monitoring and improving the metabolic health of dairy cows during the transition period. Animals (Basel) 2021; 11: 352.

상세보기
Chamberlin WG, Middleton JR, Spain JN, Johnson GC, Ellersieck MR, Pithua P. Subclinical hypocalcemia, plasma biochemical parameters, lipid metabolism, postpartum disease, and fertility in postparturient dairy cows. J Dairy Sci 2013; 96: 7001-7013.

상세보기
Curtis CR, Erb HN, Sniffen CJ, Smith RD, Powers PA, Smith MC, et al. Association of parturient hypocalcemia with eight periparturient disorders in Holstein cows. J Am Vet Med Assoc 1983; 183: 559-561.
Fadul M, Bogdahn C, Alsaaod M, Husler J, Starke A, Steiner A, et al. Prediction of calving time in dairy cattle. Anim Reprod Sci 2017; 187: 37-46.

상세보기
Ferguson JD, Galligan DT, Thomsen N. Principal descriptors of body condition score in Holstein cows. J Dairy Sci 1994; 77: 2695-2703.

상세보기
Goff JP. The monitoring, prevention, and treatment of milk fever and subclinical hypocalcemia in dairy cows. Vet J 2008; 176: 50-57.

상세보기
Goff JP, Horst RL. Physiological changes at parturition and their relationship to metabolic disorders. J Dairy Sci 1997; 80: 1260-1268.
Greiner M, Pfeiffer D, Smith RD. Principles and practical application of the receiver-operating characteristic analysis for diagnostic tests. Prev Vet Med 2000; 45: 23-41.

상세보기
Grummer RR. Etiology of lipid-related metabolic disorders in periparturient dairy cows. J Dairy Sci 1993; 76: 3882-3896.

상세보기
Grummer RR. Impact of changes in organic nutrient metabolism on feeding the transition dairy cow. J Anim Sci 1995; 73: 2820-2833.

상세보기
Herdt TH. Ruminant adaptation to negative energy balance. Influences on the etiology of ketosis and fatty liver. Vet Clin North Am Food Anim Pract 2000; 16: 215-230, v.
Holtenius P, Hjort M. Studies on the pathogenesis of fatty liver in cows. Bov pract 1990; 25: 91-94.
Jeong JK, Choi IS, Kang HG, Jung YH, Hur TY, Kim IH. Postpartum reproductive tract recovery and prevalence of health problems in dairy cows. J Vet Clin 2015; 32: 168-173.
Jeong JK, Hur TY, Jung YH, Kang HG, Kim IH. Identification of predictive biomarkers of peri- and postpartum disorders in dairy cows. Korean J Vet Res 2019; 59: 1-8.

원문보기 상세보기
Kaneene JB, Miller R, Herdt TH, Gardiner JC. The association of serum nonesterified fatty acids and cholesterol, management and feeding practices with peripartum disease in dairy cows. Prev Vet Med 1997; 31: 59-72.

상세보기
Katoh N. Relevance of apolipoproteins in the development of fatty liver and fatty liver-related peripartum diseases in dairy cows. J Vet Med Sci 2002; 64: 293-307.

상세보기
Kayano M, Kataoka T. Screening for ketosis using multiple logistic regression based on milk yield and composition. J Vet Med Sci 2015; 77: 1473-1478.

상세보기
LeBlanc S. Monitoring metabolic health of dairy cattle in the transition period. J Reprod Dev 2010; 56 Suppl: S29-S35.
LeBlanc SJ, Leslie KE, Duffield TF. Metabolic predictors of displaced abomasum in dairy cattle. J Dairy Sci 2005; 88: 159-170.

상세보기
McArt JAA, Nydam DV, Oetzel GR. Epidemiology of subclinical ketosis in early lactation dairy cattle. J Dairy Sci 2012; 95: 5056-5066.

상세보기
McSherry BJ, Lumsden JH, Valli VE, Baird JD. Hyperbilirubinemia in sick cattle. Can J Comp Med 1984; 48: 237-240.

상세보기
Mostafavi M, Seifi HA, Mohri M, Jamshidi A. Optimal thresholds of metabolic indicators of hepatic lipidosis in dairy cows. Revue Med Vet 2013; 164: 564-571.
Ospina PA, Nydam DV, Stokol T, Overton TR. Evaluation of nonesterified fatty acids and beta-hydroxybutyrate in transition dairy cattle in the northeastern United States: critical thresholds for prediction of clinical diseases. J Dairy Sci 2010; 93: 546-554.
Puppel K, Kuczynska B. Metabolic profiles of cow's blood; a review. J Sci Food Agric 2016; 96: 4321-4328.

상세보기
Quiroz-Rocha GF, LeBlanc S, Duffield T, Wood D, Leslie KE, Jacobs RM. Evaluation of prepartum serum cholesterol and fatty acids concentrations as predictors of postpartum retention of the placenta in dairy cows. J Am Vet Med Assoc 2009; 234: 790-793.

상세보기
Reid IM, Harrison RD, Collins RA. Fasting and refeeding in the lactating dairy cow. 2. The recovery of liver cell structure and function following a six-day fast. J Comp Pathol 1977; 87: 253-265.

상세보기
Reinhardt TA, Lippolis JD, McCluskey BJ, Goff JP, Horst RL. Prevalence of subclinical hypocalcemia in dairy herds. Vet J 2011; 188: 122-124.

상세보기
Ro Y, Choi W, Kim H, Kim D. Prepartal decrease in plasma total cholesterol concentration in dairy cows developed subclinical ketosis. J Vet Clin 2017; 34: 222-224.
Rukkwamsuk T, Kruip TA, Wensing T. Relationship between overfeeding and overconditioning in the dry period and the problems of high producing dairy cows during the postparturient period. Vet Q 1999; 21: 71-77.

상세보기
Sepulveda-Varas P, Weary DM, Noro M, von Keyserlingk MA. Transition diseases in grazing dairy cows are related to serum cholesterol and other analytes. PLoS One 2015; 10: e0122317.

상세보기
Van Saun RJ. Metabolic profiles for evaluation of the transition period. Am Assoc Bov Pract Conf Proc 2006; 39: 130-138.
Wang Y, Huo P, Sun Y, Zhang Y. Effects of body condition score changes during peripartum on the postpartum health and production performance of primiparous dairy cows. Animals (Basel) 2019; 9: 1159.

상세보기

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

Receiver Operating Characteristic Analysis for Prediction of Postpartum Metabolic Diseases in Dairy Cows in an Organic Farm in Korea 원문보기

Abstract ▼ AI-Helper

주제어

참고문헌 (34)

이 논문을 인용한 문헌

관련 콘텐츠

원문 보기

원문 URL 링크

이 논문과 함께 이용한 콘텐츠

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트