최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Journal of yeungnam medical science, v.39 no.4, 2022년, pp.269 - 277
Ko, Haneol (Medical Course, Jeju National University School of Medicine) , Yoon, Sang-Pil (Department of Anatomy, Jeju National University College of Medicine)
The amyloid hypothesis has been considered a major explanation of the pathogenesis of Alzheimer disease. However, failure of phase III clinical trials with anti-amyloid-beta monoclonal antibodies reveals the need for other therapeutic approaches to treat Alzheimer disease. Compared to its relatively...
1 2021 Alzheimer’s disease facts and figures Alzheimers Dement 2021 17 327 406 33756057
2 Lee JS Kang MJ Nam HJ Kim YJ Lee OJ Kim KO Korean dementia observatory 2019 (Report No. NIDR-1902-0028) [Internet] Seoul Central Dementia Center Service 2020 [cited 2021 Dec 09]. https://www.nid.or.kr/info/dataroom_view.aspx?bid=209
3 Burns A Iliffe S Alzheimer’s disease BMJ 2009 338 b158 19196745
4 Nimmrich V Draguhn A Axmacher N Neuronal network oscillations in neurodegenerative diseases Neuromolecular Med 2015 17 270 84 25920466
5 Canter RG Penney J Tsai LH The road to restoring neural circuits for the treatment of Alzheimer’s disease Nature 2016 539 187 96 27830780
6 Strüber D Herrmann CS Modulation of gamma oscillations as a possible therapeutic tool for neuropsychiatric diseases: a review and perspective Int J Psychophysiol 2020 152 15 25 32240665
7 Ballard C Gauthier S Corbett A Brayne C Aarsland D Jones E Alzheimer’s disease Lancet 2011 377 1019 31 21371747
8 Glenner GG Wong CW Alzheimer’s disease and Down’s syndrome: sharing of a unique cerebrovascular amyloid fibril protein Biochem Biophys Res Commun 1984 122 1131 5 6236805
9 Selkoe DJ Hardy J The amyloid hypothesis of Alzheimer’s disease at 25 years EMBO Mol Med 2016 8 595 608 27025652
10 Cui X Zhang F Zhang H Huang X Wang K Huang T Neuroprotective effect of optogenetics varies with distance from channelrhodopsin-2 expression in an amyloid-β-injected mouse model of Alzheimer’s disease Front Neurosci 2020 14 583628 33162881
11 Gao Y Tan L Yu JT Tan L Tau in Alzheimer’s disease: mechanisms and therapeutic strategies Curr Alzheimer Res 2018 15 283 300 28413986
12 Selkoe DJ The molecular pathology of Alzheimer’s disease Neuron 1991 6 487 98 1673054
13 Hardy JA Higgins GA Alzheimer’s disease: the amyloid cascade hypothesis Science 1992 256 184 5 1566067
14 Kamal A Almenar-Queralt A LeBlanc JF Roberts EA Goldstein LS Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP Nature 2001 414 643 8 11740561
15 Hooper NM Roles of proteolysis and lipid rafts in the processing of the amyloid precursor protein and prion protein Biochem Soc Trans 2005 33 Pt 2 335 8 15787600
16 Ohnishi S Takano K Amyloid fibrils from the viewpoint of protein folding Cell Mol Life Sci 2004 61 511 24 15004691
17 Tiraboschi P Hansen LA Thal LJ Corey-Bloom J The importance of neuritic plaques and tangles to the development and evolution of AD Neurology 2004 62 1984 9 15184601
18 Citron M Strategies for disease modification in Alzheimer’s disease Nat Rev Neurosci 2004 5 677 85 15322526
19 Oxford AE Stewart ES Rohn TT Clinical trials in Alzheimer’s disease: a hurdle in the path of remedy Int J Alzheimers Dis 2020 2020 5380346 32308993
20 Arispe N Rojas E Pollard HB Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum Proc Natl Acad Sci U S A 1993 90 567 71 8380642
21 Ekinci FJ Linsley MD Shea TB Beta-amyloid-induced calcium influx induces apoptosis in culture by oxidative stress rather than tau phosphorylation Brain Res Mol Brain Res 2000 76 389 95 10762716
22 Abramov AY Canevari L Duchen MR Calcium signals induced by amyloid beta peptide and their consequences in neurons and astrocytes in culture Biochim Biophys Acta 2004 1742 81 7 15590058
23 Boyden ES Zhang F Bamberg E Nagel G Deisseroth K Millisecond-timescale, genetically targeted optical control of neural activity Nat Neurosci 2005 8 1263 8 16116447
24 Deisseroth K Feng G Majewska AK Miesenböck G Ting A Schnitzer MJ Next-generation optical technologies for illuminating genetically targeted brain circuits J Neurosci 2006 26 10380 6 17035522
25 Tye KM Deisseroth K Optogenetic investigation of neural circuits underlying brain disease in animal models Nat Rev Neurosci 2012 13 251 66 22430017
26 Byun J Optogenetics: a new frontier for cell physiology study J Life Sci 2015 25 953 9
27 Crick F The impact of molecular biology on neuroscience Philos Trans R Soc Lond B Biol Sci 1999 354 2021 5 10670022
28 Callaway EM Katz LC Photostimulation using caged glutamate reveals functional circuitry in living brain slices Proc Natl Acad Sci U S A 1993 90 7661 5 7689225
29 Zemelman BV Lee GA Ng M Miesenböck G Selective photostimulation of genetically chARGed neurons Neuron 2002 33 15 22 11779476
30 Nagel G Szellas T Huhn W Kateriya S Adeishvili N Berthold P Channelrhodopsin-2, a directly light-gated cation-selective membrane channel Proc Natl Acad Sci U S A 2003 100 13940 5 14615590
31 Pama EA Colzato LS Hommel B Optogenetics as a neuromodulation tool in cognitive neuroscience Front Psychol 2013 4 610 24046763
32 Beck S Yu-Strzelczyk J Pauls D Constantin OM Gee CE Ehmann N Synthetic light-activated ion channels for optogenetic activation and inhibition Front Neurosci 2018 12 643 30333716
33 Gradinaru V Thompson KR Deisseroth K eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications Brain Cell Biol 2008 36 129 39 18677566
34 Witten IB Lin SC Brodsky M Prakash R Diester I Anikeeva P Cholinergic interneurons control local circuit activity and cocaine conditioning Science 2010 330 1677 81 21164015
35 Zhang F Gradinaru V Adamantidis AR Durand R Airan RD de Lecea L Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures Nat Protoc 2010 5 439 56 20203662
36 Fenno L Yizhar O Deisseroth K The development and application of optogenetics Annu Rev Neurosci 2011 34 389 412 21692661
37 Arenkiel BR Peca J Davison IG Feliciano C Deisseroth K Augustine GJ In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2 Neuron 2007 54 205 18 17442243
38 Schindler SE McCall JG Yan P Hyrc KL Li M Tucker CL Photo-activatable Cre recombinase regulates gene expression in vivo Sci Rep 2015 5 13627 26350769
39 Kawano F Okazaki R Yazawa M Sato M A photoactivatable Cre-loxP recombination system for optogenetic genome engineering Nat Chem Biol 2016 12 1059 64 27723747
40 Matarèse BF Feyen PL de Mello JC Benfenati F Sub-millisecond control of neuronal firing by organic light-emitting diodes Front Bioeng Biotechnol 2019 7 278 31750295
41 Mahmoudi P Veladi H Pakdel FG Optogenetics, tools and applications in neurobiology J Med Signals Sens 2017 7 71 9 28553579
42 Malyshev A Goz R LoTurco JJ Volgushev M Advantages and limitations of the use of optogenetic approach in studying fast-scale spike encoding PLoS One 2015 10 e0122286 25850004
43 Jasper HH Andrews HL Electro-encephalography: III. Normal differentiation of occipital and precentral regions in man Arch Neurol Psychiatr 1938 39 96 115
44 McDermott B Porter E Hughes D McGinley B Lang M O’Halloran M Gamma band neural stimulation in humans and the promise of a new modality to prevent and treat Alzheimer’s disease J Alzheimers Dis 2018 65 363 92 30040729
45 Esmaeilpour Z Kronberg G Reato D Parra LC Bikson M Temporal interference stimulation targets deep brain regions by modulating neural oscillations Brain Stimul 2021 14 55 65 33186778
46 Yuan Y Yan J Ma Z Li X Effect of noninvasive focused ultrasound stimulation on gamma oscillations in rat hippocampus Neuroreport 2016 27 508 15 27007778
47 Etter G van der Veldt S Manseau F Zarrinkoub I Trillaud-Doppia E Williams S Optogenetic gamma stimulation rescues memory impairments in an Alzheimer’s disease mouse model Nat Commun 2019 10 5322 31757962
48 Herrmann CS Fründ I Lenz D Human gamma-band activity: a review on cognitive and behavioral correlates and network models Neurosci Biobehav Rev 2010 34 981 92 19744515
49 Sohal VS How close are we to understanding what (if anything) γ oscillations do in cortical circuits? J Neurosci 2016 36 10489 95 27733600
50 Adaikkan C Tsai LH Gamma entrainment: impact on neurocircuits, glia, and therapeutic opportunities Trends Neurosci 2020 43 24 41 31836315
51 Bartos M Vida I Jonas P Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks Nat Rev Neurosci 2007 8 45 56 17180162
52 Stam CJ van Cappellen van Walsum AM Pijnenburg YA Berendse HW de Munck JC Scheltens P Generalized synchronization of MEG recordings in Alzheimer’s disease: evidence for involvement of the gamma band J Clin Neurophysiol 2002 19 562 74 12488788
53 Stam CJ van der Made Y Pijnenburg YA Scheltens P EEG synchronization in mild cognitive impairment and Alzheimer’s disease Acta Neurol Scand 2003 108 90 6 12859284
54 Koenig T Prichep L Dierks T Hubl D Wahlund LO John ER Decreased EEG synchronization in Alzheimer’s disease and mild cognitive impairment Neurobiol Aging 2005 26 165 71 15582746
55 van Deursen JA Vuurman EF Verhey FR van Kranen-Mastenbroek VH Riedel WJ Increased EEG gamma band activity in Alzheimer’s disease and mild cognitive impairment J Neural Transm (Vienna) 2008 115 1301 11 18607528
56 Başar E Emek-Savaş DD Güntekin B Yener GG Delay of cognitive gamma responses in Alzheimer’s disease Neuroimage Clin 2016 11 106 15 26937378
57 Mably AJ Colgin LL Gamma oscillations in cognitive disorders Curr Opin Neurobiol 2018 52 182 7 30121451
58 Klein AS Donoso JR Kempter R Schmitz D Beed P Early cortical changes in Gamma oscillations in Alzheimer’s disease Front Syst Neurosci 2016 10 83 27833535
59 da Silva VF Ribeiro AP Dos Santos VA Nardi AE King AL Calomeni MR Stimulation by light and sound: therapeutics effects in humans: systematic review Clin Pract Epidemiol Ment Health 2015 11 150 4 26161130
60 Calomeni MR Furtado da Silva V Velasques BB Feijó OG Bittencourt JM Ribeiro de Souza E Silva AP Modulatory effect of association of brain stimulation by light and binaural beats in specific brain waves Clin Pract Epidemiol Ment Health 2017 13 134 44 29238390
61 Driver JE Racca C Cunningham MO Towers SK Davies CH Whittington MA Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP) Eur J Neurosci 2007 26 1280 8 17767505
62 Peña-Ortega F Amyloid beta-protein and neural network dysfunction J Neurodegener Dis 2013 2013 657470 26316994
63 Yizhar O Fenno LE Davidson TJ Mogri M Deisseroth K Optogenetics in neural systems Neuron 2011 71 9 34 21745635
64 Kellar KJ Whitehouse PJ Martino-Barrows AM Marcus K Price DL Muscarinic and nicotinic cholinergic binding sites in Alzheimer’s disease cerebral cortex Brain Res 1987 436 62 8 3690354
65 Marutle A Warpman U Bogdanovic N Nordberg A Regional distribution of subtypes of nicotinic receptors in human brain and effect of aging studied by (+/-)-[3H]epibatidine Brain Res 1998 801 143 9 9729344
66 Perry DC Dávila-García MI Stockmeier CA Kellar KJ Increased nicotinic receptors in brains from smokers: membrane binding and autoradiography studies J Pharmacol Exp Ther 1999 289 1545 52 10336551
67 Perry E Martin-Ruiz C Lee M Griffiths M Johnson M Piggott M Nicotinic receptor subtypes in human brain ageing, Alzheimer and Lewy body diseases Eur J Pharmacol 2000 393 215 22 10771016
68 Bell KA Shim H Chen CK McQuiston AR Nicotinic excitatory postsynaptic potentials in hippocampal CA1 interneurons are predominantly mediated by nicotinic receptors that contain α4 and β2 subunits Neuropharmacology 2011 61 1379 88 21878344
69 Yang X Yao C Tian T Li X Yan H Wu J A novel mechanism of memory loss in Alzheimer’s disease mice via the degeneration of entorhinal-CA1 synapses Mol Psychiatry 2018 23 199 210 27671476
70 Jarzebowski P Tang CS Paulsen O Hay YA Impaired spatial learning and suppression of sharp wave ripples by cholinergic activation at the goal location Elife 2021 10 e65998 33821790
71 Andrews-Zwilling Y Gillespie AK Kravitz AV Nelson AB Devidze N Lo I Hilar GABAergic interneuron activity controls spatial learning and memory retrieval PLoS One 2012 7 e40555 22792368
72 Roy DS Arons A Mitchell TI Pignatelli M Ryan TJ Tonegawa S Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease Nature 2016 531 508 12 26982728
73 Perusini JN Cajigas SA Cohensedgh O Lim SC Pavlova IP Donaldson ZR Optogenetic stimulation of dentate gyrus engrams restores memory in Alzheimer’s disease mice Hippocampus 2017 27 1110 22 28667669
74 Arendash GW Schleif W Rezai-Zadeh K Jackson EK Zacharia LC Cracchiolo JR Caffeine protects Alzheimer’s mice against cognitive impairment and reduces brain beta-amyloid production Neuroscience 2006 142 941 52 16938404
75 Dall’Igna OP Fett P Gomes MW Souza DO Cunha RA Lara DR Caffeine and adenosine A(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice Exp Neurol 2007 203 241 5 17007839
76 Cunha GM Canas PM Melo CS Hockemeyer J Müller CE Oliveira CR Adenosine A2A receptor blockade prevents memory dysfunction caused by beta-amyloid peptides but not by scopolamine or MK-801 Exp Neurol 2008 210 776 81 18191838
77 Li P Rial D Canas PM Yoo JH Li W Zhou X Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory Mol Psychiatry 2015 20 1339 49 25687775
78 Cardin JA Carlén M Meletis K Knoblich U Zhang F Deisseroth K Driving fast-spiking cells induces gamma rhythm and controls sensory responses Nature 2009 459 663 7 19396156
79 Thomson H How flashing lights and pink noise might banish Alzheimer’s, improve memory and more Nature 2018 555 20 2
80 Iaccarino HF Singer AC Martorell AJ Rudenko A Gao F Gillingham TZ Gamma frequency entrainment attenuates amyloid load and modifies microglia Nature 2016 540 230 5 27929004
81 Zhang Z Jing Y Ma Y Duan D Li B Hölscher C Driving GABAergic neurons optogenetically improves learning, reduces amyloid load and enhances autophagy in a mouse model of Alzheimer’s disease Biochem Biophys Res Commun 2020 525 928 35 32173530
82 Park K Lee J Jang HJ Richards BA Kohl MM Kwag J Optogenetic activation of parvalbumin and somatostatin interneurons selectively restores theta-nested gamma oscillations and oscillation-induced spike timing-dependent long-term potentiation impaired by amyloid β oligomers BMC Biol 2020 18 7 31937327
83 Chung H Park K Jang HJ Kohl MM Kwag J Dissociation of somatostatin and parvalbumin interneurons circuit dysfunctions underlying hippocampal theta and gamma oscillations impaired by amyloid β oligomers in vivo Brain Struct Funct 2020 225 935 54 32107637
84 Wilson CA Fouda S Sakata S Effects of optogenetic stimulation of basal forebrain parvalbumin neurons on Alzheimer’s disease pathology Sci Rep 2020 10 15456 32963298
85 Kastanenka KV Calvo-Rodriguez M Hou SS Zhou H Takeda S Arbel-Ornath M Frequency-dependent exacerbation of Alzheimer’s disease neuropathophysiology Sci Rep 2019 9 8964 31221985
86 Huang LK Chao SP Hu CJ Clinical trials of new drugs for Alzheimer disease J Biomed Sci 2020 27 18 31906949
87 Marshall E Gene therapy death prompts review of adenovirus vector Science 1999 286 2244 5 10636774
88 Kim GU Kim HI Chung E Towards human clinical application of emerging optogenetics technology Biomed Eng Lett 2011 1 207 12
89 Bostancıklıoğlu M An update on memory formation and retrieval: an engram-centric approach Alzheimers Dement 2020 16 926 37 32333509
90 Suberbielle E Sanchez PE Kravitz AV Wang X Ho K Eilertson K Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β Nat Neurosci 2013 16 613 21 23525040
91 Yamamoto K Tanei ZI Hashimoto T Wakabayashi T Okuno H Naka Y Chronic optogenetic activation augments aβ pathology in a mouse model of Alzheimer disease Cell Rep 2015 11 859 65 25937280
92 Wu JW Hussaini SA Bastille IM Rodriguez GA Mrejeru A Rilett K Neuronal activity enhances tau propagation and tau pathology in vivo Nat Neurosci 2016 19 1085 92 27322420
93 Gradinaru V Mogri M Thompson KR Henderson JM Deisseroth K Optical deconstruction of parkinsonian neural circuitry Science 2009 324 354 9 19299587
94 Zalocusky KA Fenno LE Deisseroth K Current challenges in optogenetics Hegemann P Sigrist S Optogenetics Berlin De Gruyter 2013 23 34
95 Kravitz AV Freeze BS Parker PR Kay K Thwin MT Deisseroth K Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry Nature 2010 466 622 6 20613723
96 Tsai HC Zhang F Adamantidis A Stuber GD Bonci A de Lecea L Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning Science 2009 324 1080 4 19389999
97 Elkouzi A Vedam-Mai V Eisinger RS Okun MS Emerging therapies in Parkinson disease: repurposed drugs and new approaches Nat Rev Neurol 2019 15 204 23 30867588
98 Berlinguer-Palmini R Narducci R Merhan K Dilaghi A Moroni F Masi A Arrays of microLEDs and astrocytes: biological amplifiers to optogenetically modulate neuronal networks reducing light requirement PLoS One 2014 9 e108689 25265500
99 Iwai Y Honda S Ozeki H Hashimoto M Hirase H A simple head-mountable LED device for chronic stimulation of optogenetic molecules in freely moving mice Neurosci Res 2011 70 124 7 21238511
100 Zhang Y Castro DC Han Y Wu Y Guo H Weng Z Battery-free, lightweight, injectable microsystem for in vivo wireless pharmacology and optogenetics Proc Natl Acad Sci U S A 2019 116 21427 37 31601737
※ AI-Helper는 부적절한 답변을 할 수 있습니다.