[논문]일개 보건지소에 내원한 급성기 후 코로나-19 환자들의 특성 및 한의 치료 효과 분석: 사례군 연구

유창환; 김관일; 정희재; 이범준

doi:10.13048/jkm.23021

일개 보건지소에 내원한 급성기 후 코로나-19 환자들의 특성 및 한의 치료 효과 분석: 사례군 연구
Effects of Korean Medicine Treatment at Public Health Center for Post-acute COVID-19 Patients: A Retrospective Case-series of 11 patients 원문보기

Journal of Korean Medicine = 대한한의학회지, v.44 no.2, 2023년, pp.132 - 148

유창환 (음성군 보건소 대소보건지소) , 김관일 (경희대학교 대학원 임상한의학과 폐계내과학교실) , 정희재 (경희대학교 대학원 임상한의학과 폐계내과학교실) , 이범준 (경희대학교 대학원 임상한의학과 폐계내과학교실)

Abstract ▼ AI-Helper

Objectives: The purpose of this study is to determine the clinical features of post-acute COVID-19 syndrome and the effectiveness and safety of Korean medicine treatment at the Public health center. Methods: The study was conducted among 11 patients with post-acute COVID-19 syndrome who attended a single public health center from January to December 2022. We retrospectively analyzed the charts of 11 patients and collected clinical characteristics, previous treatments, Korean medicine treatments, outcome variables (Numeral Rating Scale (NRS), Leicester Cough Questionnaire (LCQ), Visual Analog Scale (VAS)), adverse events, etc. Results: Of the 11 patients, six were women, and the average age of all patients was 68.27±12.31 years. The most common symptom were cough(n=9, 81.82%) and sore throat(n=9, 81.82%), followed by sputum, fatigue, rhinorrhea, and loss of appetite, etc. All 11 patients were treated with herbal medicine, with Samso-eum(n=6, 54.55%), Yeonkyopaedok-san(n=5, 45.45%), and Haengso-tang(n=3, 27.27%) being the most commonly used. After herbal medicine treatment, the median cough NRS decreased from 5 to 1, and the median sore throat NRS decreased from 4 to 1, both of which were statistically significant. One patient reported adverse event of dyspepsia and heartburn, but it was mild. Conclusions: The study presented the clinical features of the post-acute COVID-19 syndrome and suggested that Korean medicine treatment at public health centers may be effective and safe in alleviating associated symptoms.

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표/그림 (7)

그림 Fig. 1 Flow chart for subjects selection
표 Table 2. Frequency of the Symptoms in Patients
표 Table 1. Case Summary of Eleven Patients
표 Table 1. Case Summary of Eleven Patients (Ccontinue)
그림 Fig. 2. Frequency of Herbal Medicine Prescriptions SSE; Samso-eum, YKPDS; Yeonkyopaedok-san, HST; Haengso-tang, SCKBT; Samchulkunbi-tang, SMS; Saengmaek-san, BJIGT; Bojungikgi-tang, BHSST; Banhasasim-tang
그림 Fig. 3. Change of Symptom NRS Before and After Treatments. a) Cough(n=7) The median pre-treatment NRS is 5 with an interquartile range (IQR) of 2.00, and the median post-treatment NRS is 1 with an IQR of 2.00, b) Sore throat(n=7) The median pre-treatment NRS is 4 with an IQR of 2.50, and the median post-treatment NRS is 1 with an IQR of 1.50 p-value: Wilcoxon signed rank test * p < 0.05
표 Table 3. Numeral Rating Scale(NRS) Change of Patients symptoms(Others)

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