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TSG101 Physically Interacts with Linear Ubiquitin Chain Assembly Complex (LUBAC) and Upregulates the TNFα-Induced NF-κB Activation 원문보기

Molecules and cells, v.46 no.7, 2023년, pp.430 - 440  

Eunju Kim (Laboratory of Cell Death and Human Diseases, Department of Life Sciences, Korea University) ,  Hyunchu Cho (Laboratory of Cell Death and Human Diseases, Department of Life Sciences, Korea University) ,  Gaeul Lee (Laboratory of Cell Death and Human Diseases, Department of Life Sciences, Korea University) ,  Heawon Baek (Laboratory of Cell Death and Human Diseases, Department of Life Sciences, Korea University) ,  In Young Lee (Laboratory of Cell Death and Human Diseases, Department of Life Sciences, Korea University) ,  Eui-Ju Choi (Laboratory of Cell Death and Human Diseases, Department of Life Sciences, Korea University)

Abstract AI-Helper 아이콘AI-Helper

Linear ubiquitin chain assembly complex (LUBAC) is a ubiquitin E3 ligase complex composed of HOIP, HOIL-1L, and SHARPIN that catalyzes the formation of linear/M1-linked ubiquitin chain. It has been shown to play a pivotal role in the nuclear factor (NF)-κB signaling induced by proinflammatory...

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참고문헌 (38)

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