[논문]종이 기반 전기화학 센서의 연구 동향

서민지

doi:10.5229/jkes.2024.27.1.1

[국내논문] 종이 기반 전기화학 센서의 연구 동향
A Review on Paper-based Electrochemical Sensors

전기화학회지 = Journal of the Korean Electrochemical Society, v.27 no.1, 2024년, pp.1 - 7

서민지 (한국교원대학교 화학교육과)

초록
AI-Helper

신체에 부착하는 웨어러블(wearable) 센서 및 현장 진단 검사(point-of-care testing)가 용이한 센서의 필요성이 부각되면서, 종이를 기반으로 하는 센서들이 활발히 연구되어왔다. 종이는 매우 저렴하면서도 가볍고 유연할 뿐만 아니라, 표면에 카본과 같은 전도성 물질 및 왁스와 같은 소수성 물질을 입히기 쉽다. 또한, 종이를 이루는 셀룰로오스 섬유에 의한 모세관 현상으로 외부 힘 없이 용액의 흐름을 유도할 수 있어 웨어러블 전기화학 센서의 플랫폼으로 특히 주목받고 있다. 이에 따라, 다양한 분석 물질들을 전기화학적인 방법으로 검출하는 종이 기반 센서들이 활발히 개발되어 왔다. 특히, 분석 물질에 따른 전류 값 이외에도, 전기화학 발광현상(electrochemiluminescence) 혹은 전기 변색 물질(electrochromic material)을 도입하여 시각적으로 데이터를 나타내는 센서들도 보고되어 왔다. 이 논문에서는 종이 기반 전기화학 센서들의 제작법 및 다양한 활용 전략을 사례 중심으로 소개하였다.

Abstract ▼ AI-Helper

With the increasing demand for wearable sensors that are capable of point-of-care testing, paper-based sensors have been extensively studied. Paper is not only extremely cost-effective but also lightweight and flexible, and it is easy to apply conductive materials such as carbon and hydrophobic substances like wax to its surface. Moreover, the capillary action caused by cellulose fibers in paper allows the flow of liquid without help from external forces, making paper a particularly promising platform for wearable electrochemical sensors. Accordingly, paper-based sensors for detecting various analytes through electrochemical methods have been actively developed. Recently, paper-based electrochemical sensors that utilize electrochemiluminescence (ECL) or electrochromic materials for the optical read-out have been reported. This review introduces the basic fabrication methods and various application strategies of paper-based electrochemical sensors.

주제어

표/그림 (3)

그림 Fig. 1. Scheme describing the fabrication process of paper-based electrochemical sensors through (a) screen printing of carbon ink, (b) ink-jet printing (copyright 2015, The Electrochemical Society), and (c) laser-induced graphene (copyright 2021, Wiley)
그림 Fig. 2. Various strategies for paper-based electrochemical sensors. (a) Paper analytic device based on chromatographic separation of ascorbic acid and dopamine (copyright 2015, American Chemical Society), (b) Microfluidic paper device comprised of an origami folding paper and a movable reagent-stored pad and their two types of configurations (flowthrough and stopped-flow) (copyright 2019, The Electrochemical Society), and (c) three-dimensional paper-based microfluidic electrochemical integrated device (3D-PMED) comprised of five layers, enabling real-time monitoring of sweat metabolites (copyright 2019, Royal Society of Chemistry).
그림 Fig. 3. Paper-based electrochemical sensors utilizing electrochemiluminescence and electrochromic materials as the optical read-out. (a) ECL is displayed upon binding between [Ru(phen)2dppz]²⁺ and DNA, enabling ECL assay on the carbon bipolar electrode (copyright 2016, American Chemical Society). (b) Prussian blue/polyaniline deposited on gold nanoparticle film is used as an electrochromic indicator (copyright 2015 American Chemical Society). (c) ITO nanoparticles on screen printed carbon is used as a substrate for polyaniline, enabling the visualization of glucose concentration (copyright 2022, Elsevier).

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표제어: PCR

동의어: Packet Collision Rate

용어 설명 출처 목록 (6)

용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

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