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[국내논문] 쥐오줌풀 정유의 향기성분 동정과 생리활성 효과 연구
Identification of Aromatic Components and Physiological Activities of Valeriana fauriei Essential Oil

Journal of the Korean Applied Science and Technology = 한국응용과학기술학회지, v.41 no.3, 2024년, pp.733 - 744  

정지은 (남부대학교 향장미용학과) ,  정숙희 (남부대학교 향장미용학과)

초록
AI-Helper 아이콘AI-Helper

본 연구는 국내 천연 자생 식물인 쥐오줌풀을 정유 추출하여 향기 성분 분석결과를 기반으로 항산화(DPPH, ABTS), 세포생존율(MTS), 항염(Nitric oxide)실험을 수행하였다. 향기성분 분석결과 쥐오줌풀의 대표 유효 성분인 ester류의 bornyl acetate가 47.88%로 타지역에 비해 높은 함유량을 나타났으며 patchouli alcohol (18.9%), camphene (11.37%), camphene (11.37%), α-Pinene (5.44%), D-limonene (1.11%)등이 동정되었다. 항산화 활성인 DPPH 라디칼 소거능이 250 µl/ml에서 73.62%, ABTS 라디칼 소거능이 250 µl/ml에서 82.17%을 보였으며, 세포독성이 확인되지 않은 5 µl/ml의 농도에서 NO 생성 저해능은 대조군에 대비 62.02%로 감소함을 나타났다. 이를 통해 기능성 제품으로의 활용 가능성을 과학적으로 검증하여 쥐오줌풀 정유를 활용한 연구분야에 일부 기여할 수 있을 것이라 기대되는 바이다.

Abstract AI-Helper 아이콘AI-Helper

This study extracted essential oil from the native Korean plant Valeriana fauriei and performed fragrance component analysis, antioxidant (DPPH, ABTS), cell viability (MTS), and anti-inflammatory (Nitric oxide) experiments based on the analysis results. The fragrance component analysis revealed that...

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표/그림 (6)

참고문헌 (58)

  1. H. W. Choi, The Virtual Economy Era?Created by Metaverse Is Coming. pp.?80-83, Hanz Media, (2021).? 

  2. Y. Kim, "How to Combine Traditional?Incense Culture and the Incense Industry?-A Case Study of the Global Incense?Producer 'Nippon Koudou", Journal of?Japanese Language and Literature, Vol.87,?pp. 227-242, (2020).? 

  3. ???一. "香りの機能性と?用. AROMA?RESEARCH, Vol.10, No.4 pp. 324-335,?(2009).? 

  4. H. S. Lee, "A Proposition to the Development of Emotional Contents in The?Digital Cultural Environment - Centering on USB Ceramic Aroma Diffuser", The?Korean Society of Science & Art, Vol.6,?pp. 111-121, (2010).? 

  5. R. Amorati, M. C. Foti, L. Valgimigli,?"Antioxidant activity of essential oils",?Journal of Agricultural and Food Chemistry, Vol.61, No.46 pp. 10835-10847, (2013).? 

  6. R. Salgado-Garciglia, J. Lopez-Meza, R.?Torres-Martinez, A. Ochoa-Zarzosa, A.?Saavedra-Molina, "Antioxidant activity of?the essential oil and its major terpenes of?Satureja macrostema (moc. And sesse ex benth.) briq", Pharmacognosy Magazine, Vol.13, No.4 pp. 875-880, (2018).? 

  7. M. J. Jeong, J. Yang, W. S. Choi, J. W.?Kim, S. J. Kim, M. J. Park, "Chemical?compositions and antioxidant activities of?essential oil extracted from Neolitsea?aciculata (Blume) Koidz leaves", Journal of?the Korean Wood Science and Technology,?Vol.45, No.1 pp. 96-106, (2017).? 

  8. F. Nazzaro, F. Fratianni, R. Coppola, V.?Feo, "Essential oils and antifungal activity",?Pharmaceuticals (Basel), Vol.10, No.4 pp.?86-106, (2017).? 

  9. M. D'agostino, N. Tesse, J. P. Frippiat, M.?Machouart, A. Debourgogne, "Essential oils?and their natural active compounds?presenting antifungal properties", Molecules, Vol.24, No.20 pp. 3713-3734, (2019).? 

  10. A. Tripathi, S. Upadhyay, M. Bhuyan, P.?Bhattacharya, "A review on prospects of?essential oils as biopesticide in insect-pest?management", Journal of Pharmacognosy?and Phytotherapy, Vol.1, No.5 pp.?052-063, (2009).? 

  11. A. Ayvaz, O. Sagdic, S. Karaborklu, I.?Ozturk, "Insecticidal activity of the?essential oils from different plants against?three stored-product insects", Journal of?Insect Science, Vol.10, No.1 pp. 21-32,?(2010). 

  12. F. Bakkali, S. Averbeck, D. Averbeck, M.?Idaomar, "Biological effects of essential?oils: A review", Food and Chemical?Toxicology, Vol.46, No.2 pp. 446-475,?(2008).? 

  13. S. Chouhan, K. Sharma, S. Guleria,?"Antimicrobial activity of some essential?oils-present status and future perspectives",?Medicines, Vol.4, No.3 pp. 58-79, (2017).? 

  14. H. J. Min, C. S. Kim, H. J. Hyun, Y. S.?Bae, "Essential oil analysis of Illicium?anistum L. extracts", Journal of the?Korean Wood Science and Technology, Vol.45, No.6 pp. 682-688, (2017).? 

  15. C. Ahn, M. J. Park, J. W. Kim, J. Yang,?S. S. Lee, E. B. Jeung, "Cytotoxic?evaluation of plant essential oils in human?skin and lung cells", Journal of the Korean?Wood Science and Technology, Vol.46,?No.2 pp. 166-177, (2018).? 

  16. F. Sutili, A. L. Murari, L. L. Silva, L.?Gressler, B. Heinzmann, A. Vargas, D.?Schmidt, B. Baldisserotto, "The use of?Ocimum americanum essential oil against?the pathogens Aeromonas hydrophila and?Gyrodactylus sp. in silver catfish (Rhamdia?quelen)", Letters in Applied Microbiology, Vol.63, No.2 pp. 82-88, (2016).? 

  17. C. H. Cho, Y. H. Choi, K. S. Kim,?"Differences of major compounds in?Valerian fauriei var. dasycarpa Hara, V.?officinalis var lalfolia Miq and V. wallichii?DC", Korean Journal of Medicinal Crop?Science, Vol.3 pp. 217-225, (1992).? 

  18. C. H. Cho, Y. H. Choi, K. S. Kim,?"Differences of major compounds in?Valerian fauriei var. dasycarpa HARA and?Valerian officinalis L. grown at different?places in Korea", Korean Journal of?Medicinal Crop Science, Vol.4, pp.?109-113, (1996).? 

  19. C. M. Kim, K. S. Ryu, "Chemical Study?of Domestic Plants in the Valeriana Genus?(Part II): Chemical Study of Gwangneung?Valeriana", Korean Journal of Pharmacognosy, Vol.8, No.3 pp. 95-101, (1977).? 

  20. Y. T. Kim, "Study on the Essential Oil?Components of Korean Valeriana?(Vaieriana fauriei var. dasycarpa Hara)",?Journal of the Korean Society for Applied?Biological Chemistry, Vol.14, No.1 pp.?66-78, (1992).? 

  21. S. M. Ross, "Sleep disorders: A single dose?administration of valerian/hops fluid?extract (dormeasan) is found to be?effective in improving sleep", Holistic?Nursing Practice, Vol.23, pp. 53-256,?(2009).? 

  22. J. Leuschner, J. Muller, M. Rudmann,?"Characterisation of the central nervous?depressant activity of a commercially?available valerian root extract", Arzneimittelforschung, Vol.43, pp. 638-641, (1993).? 

  23. P. J. Houghton, "The biological activity of?valerian and related plants", Journal of?Ethnopharmacology, Vol.22, pp. 121-174,?(1988).? 

  24. S. K. Lee, S. W. Jeon, I. H. Jung, S. G.?Park, S. B. Lee, H. S. Lee, B. Y. Park,?"Insecticidal effects on brown-winged?leafhopper (Ricania shantungensis) in?Valeriana fauriei essential oil extracted in?3 different ways", Journal of Applied?Biological Chemistry, Vol.66, No.1 pp.?47-50, (2018).? 

  25. M. S. Blois, "Antioxidant determinations?by the use of a stable free radical",?Nature, Vol.181, pp. 1199-1200, (1958).? 

  26. P. Nicoletta, "Screening of dietary carotenoids and carotenoid-rich fruit?extracts for antioxidant activities applying?2, 2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) radical cation?decolorization assay", Methods Enzymol, Vol.299, pp. 379-389, (1999).? 

  27. M. B. Arnao, "Some methodological?problems in the determination of?antioxidant activity using chromogen?radicals: A practical case", Trends in Food?Science &Technology, Vol.11, pp.?419-421, (2000).? 

  28. A. Desai, T. Vyas, M. Amiji, "Cyroroxicity?and apoptosis enhancement in brain tumor?cells upon coadministration of paclitaxel?and ceramide in nanoemulsion formulations", Journal of Pharmaceutical Sciences, Vol.97, pp. 2745, (2008).? 

  29. A. Murakami, M. Nakashima, T. Koshiba,?T. Maoka, H. Nishino, M. Yano, T.?Sumida, O.K. Kim, K. Koshimizu, H.?Ohigashi, "Modifying effects of carotenoids on superoxide and nitric oxide generation?from stimulated leukocytes", Cancer Letter, Vol.149, No.1-2 pp. 115-123, (2000).? 

  30. H. C. Chang, C. Hwan, C. L. Jong, Y.?H. Kim, K. S. Kim, T. J. Ahn, O. K.?Han, "Odor Characteristics of Essential Oil?of Valeriana fauriei var dasycarpa HARA",?Korean Journal of Medicinal Crop Science, Vol.4, No.1 pp. 31-37, (1996).? 

  31. S. Arctander, Perfume and Flavor?Chemicals, pp. 353, Montclair, (1969).? 

  32. J. R. G. D. S. Almeida, G. R. Souza, J.?C. Silva, "Borneol, a bicyclic monoterpene?alcohol, reduces nociceptive behavior and?inflammatory response in mice", The?Scientific World Journal, pp. 5, (2013).? 

  33. H. Guanying, P. Cheng, X. Xie, Z.?Sanyin, C. Xiaoyu, "Availability, pharmaceutics, security, pharmacokinetics, and?pharmacological activities of patchouli?alcohol", Evidence-based complementary?and alternative medicine, pp. 9, (2017).? 

  34. P. K. Koukos, K. I. Papadopoulou, D. T.?Patiaka, A. D. Papagiannopoulos, "Chemical?composition of essential oils from needles?and twigs of balkan pine (Pinus peuce?Grisebach) grown in Northern Greece",?Journal of Agricultural and Food?Chemistry, Vol.48, pp. 1266-1268, (2000).? 

  35. Y .S. Lim, M. J. Bae, S. H. Lee, "Antimicrobial effects of Pinus densiflora?Sieb. et Zucc. ethanol extract on Listeria?monocytogenes", Journal of the Korean?Society of Food Science and Nutrition,?Vol.31, pp. 333-337, (2002).? 

  36. W. C. Zeng, Z. Zhang, H. Gao, L. R.?Jia, Q. He, "Chemical composition,?antioxidant, and antimicrobial activities of?essential oil from pine needle (Cedrus?deodara)", Journal of Food Science, Vol.77,?pp. 824-829, (2012).? 

  37. P. Dhar, P, "Synthesis, antimicrobial?evaluation, and structure-activity relationship of α?pinene derivatives", Journal?of Agricultural and Food Chemistry, Vol.62, pp. 3548-3552, (2014).? 

  38. D. Preeti, C. PuiYee, C. T. Daniel, K.?Fadi, G. Sarah, S. L. Teresa, D. Ellen, K.?R. Prashant, W. Geeta, "Phytoncides?(wood essential oils) induce human natural?killer cell activity", Immunopharmacology?and Immunotoxicology, Vol.28, pp. 1-22,?(2006).? 

  39. K Kawakami, M Kawamoto, M Nomura,?H Otani, T Nabika, T Gonda, "Effects of?phytoncides on blood pressure under?restraint stress in SHRSP", Clinical and?Experimental Pharmacology and Physiology, Vol.31, No. pp. 27-28, (2004).? 

  40. H. Yang, J. Woo, A. N. Pae, M. Y. Um,?N. C. Cho, K. D. Park, M. Yoon, J.?Kim, C. J. Lee, S. Cho, "α-Pinene, a major constituent of pine tree oils,?enhances non-rapid eye movement sleep in?mice through GABAA-benzodiazepine?receptors", Molecular Pharmacology, Vol.90, pp. 530-539, (2016).? 

  41. I. Orhan, E. Kupeli, M. Aslan, M. Kartal,?E. Yesilada, M, "Bioassay-guided evaluation?of antiinflammatory and antinociceptive activities of pistachio, Pistacia vera L",?Journal of Ethnopharmacology, Vol.105,?pp. 235-240, (2006).? 

  42. P. Sharon, C. Philippe, E. Sandra, M.?Briley, "Validation of open: closed arm entries in an elevated plus-maze as a measure of anxiety in the rat", J Neurosci?Methods, Vol.14, pp. 149-167 (1985).? 

  43. H. S. Choi, B. S. Ko, H. D. Kim, K. B.?Hong, H. J. Suh, "Effect of valerian/hop?mixture on sleep-related behaviors in?Drosophila melanogaster", Biological and?Pharmaceutical Bulletin, Vol.40, pp.?1101-1110 (2017).? 

  44. J. Wang, J. Zhao, H. Liu, L. Zhou, Z.?Liu, J. Wang, J. Han, Z. Yu, F. Yang,?"Chemical analysis and biological activity?of the essential oils of two valerianaceous?species from China: Nardostachys?chinensis and Valeriana officinalis",?Molecules, Vol.15, pp. 6411-6422 (2010).? 

  45. R. Thanan, S. Oikawa, Y. Hiraku, S.?Ohnishi, N. Ma, S. Pinlaor, P. Yongvanit,?S. Kawanishi, M. Murata, "Oxidative?stress and its significant roles in?neurodegenerative diseases and cancer",?Journal of Molecular Sciences, Vol.16, pp.?193-217 (2015).? 

  46. M. B. Arnao, "Some methodological?problems in the determination of?antioxidant activity using chromogen?radicals: A practical case", Trends in Food?Science &Technology, Vol.11, pp. 419-421?(2000).? 

  47. S. A. Kang, J. A. Han, K. H. Jang, R. W.?Choue, "DPPH radical scavenger activity?and antioxidant effects of Cham-Dang-Gui (Angelica gigas)", Journal of the?Korean Society of Food Science and?Nutrition, Vol.33, pp. 1112-1118 (2004).? 

  48. J. M. Kyu, "Monitoring the changes of?2,2-diphenyl-1-picrylhydrazyl (DPPH)?absorbance and oxidation products in?thermally oxidized linoleic acid", Ph.D.?Thesis, Seoul National University, Korea,?pp. 5-6 (2010).? 

  49. H. E. Park, J. A. Hyun, E. B. Kang, H. J.?Kwon, S. H. Beom, D. G. Han, B. J. An,?"Anti-inflammatory and antioxidant?activities of Rosa multiflora", Korean?Journal of Food Preservation, Vol.29, pp.?327-338 (2022).? 

  50. D. H. Yoo, I. C. Lee, "Antioxidant effect?and iNOS, COX-2 expression inhibition on RAW 264.7 cell of Mangifera indica L.?leafs", Journal of Life Sciences, Vol.30, pp.?783-790 (2020).? 

  51. S. M. Lee, C. D. Kim, "Antioxidant effect?of leaf, stem, and root extracts of?Zingiber officinale as cosmetic materials",?Asian Journal of Beauty and Cosmetology, Vol.19, No.1 pp. 23-33 (2021).? 

  52. K. A. Jang, Y. H. Park, Y. J. Hwang, H.?R. Kim, "Evaluation of anti-inflammatory?effect of Solanum melongena L. in?LPS-stimulated Raw 264.7 cells based on the cooking method", Korean Journal of?Food and Cookery Science, Vol.37, pp.?457-466 (2021).? 

  53. H. S. Ryu, M. J. Lee, J. R. Ham, R. Y.?Choi, H. I. Lee, H. J. Lee, Y. J. Son, M.?K. Lee, "Anti-inflammatory effects of?soybean embryo extract in LPS-stimulated?Raw 264.7 macrophages", Korean Journal?of Food and Cookery Science, Vol.48, pp.?1303-1309 (2019).? 

  54. M. W. Choi, J. I. Kim, "Anti-inflammatory effect of ethyl acetate?fraction isolated from Undaria pinnatifida on lipopolysaccharides-stimulated Raw 264.7 cells", Korean Journal of Fisheries?and Aquatic Sciences, Vol.46, pp. 384-392?(2013).? 

  55. H. J. Park, J. S. Lee, J. D. Lee, N. J.?Kim, J. H. Pyo, J. M. Kang, I. H. Choe,?S. Y. Kim, B. S. Shim, J. H. Lee, S. B. N.?Lim, "The Anti-inflammatory Effect of?Cinnamomi Ramulus", Journal of Korean?Oriental Medicine, Vol. 26, No. 2, pp.?140-151, (2005).? 

  56. J. Y. Baek, K. S. Kang, A. Y. Lee, H. Y.?Kim, "Anti-inflammatory Property of Chicken Feet, Acanthopanax, and?Eucommia ulmoides Oliver Mixture?Extract in LPS-stimulated RAW 264.7?Macrophage Cells". Korean Society for?Biotechnology and Bioengineering Journal,?Vol. 35, No. 4, pp. 330-336, (2020).? 

  57. Z. J. Zhao, Y. L. Sun, X. F. Ruan,?"Bornyl acetate: A promising agent in?phytomedicine for inflammation and?immune modulation", Phytomedicine, Vol.?114, 154781, (2023).? 

  58. S. B. Raphaelle, B. L. Sanchez Ortiz, A.?C. M. Pereira, H. Keita, J. C. T.?Carvalho, "Rosmarinus officinalis essential?oil: A review of its phytochemistry, anti-inflammatory activity, and mechanisms of?action involved", Journal of Ethnopharmacology, Vol. 229, pp. 29-45, (2019).? 

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