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[해외논문] Biogenesis of Polytopic Membrane Proteins: Membrane Segments Assemble within Translocation Channels prior to Membrane Integration 원문보기

Cell, v.85 no.3, 1996년, pp.379 - 389  

Borel, Angela C (Laboratory of Cellular Biophysics, Rockefeller University, New York, New York 10021, USA) ,  Simon, Sanford M (Laboratory of Cellular Biophysics, Rockefeller University, New York, New York 10021, USA)

Abstract AI-Helper 아이콘AI-Helper

AbstractThe initial steps in the biogenesis of membrane proteins parallel that of secretory proteins. The translocation of membrane proteins, however, must be interrupted prior to the complete traversal of the membrane. This is followed by their folding and integrating into the lipid bilayer. We hav...

참고문헌 (53)

  1. J. Cell Biol. Anderson 93 501 1982 10.1083/jcb.93.2.501 Signal recognition protein is required for the integration of acetylcholine receptor δ subunit, a transmembrane glycoprotein, into the endoplasmic reticulum membrane 

  2. Proc. Natl. Acad. Sci. USA Blobel 77 1496 1980 10.1073/pnas.77.3.1496 Intracellular protein topogenesis 

  3. J. Cell Biol. Blobel 67 852 1975 10.1083/jcb.67.3.852 Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components 

  4. J. Mol. Biol. Blobel 26 293 1967 10.1016/0022-2836(67)90298-7 Studies on free and membrane-bound ribosomes in rat liver. II. Interaction of ribosomes and membranes 

  5. Cell Chen 47 381 1986 10.1016/0092-8674(86)90595-7 Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells 

  6. Cell Crowley 78 461 1994 10.1016/0092-8674(94)90424-3 Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore 

  7. Nature Denning 358 761 1992 10.1038/358761a0 Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive 

  8. Nature Friedlander 318 338 1985 10.1038/318338a0 Bovine opsin has more than one signal sequence 

  9. J. Cell Biol. Fujiki 93 97 1982 10.1083/jcb.93.1.97 Isolation of intracellular membranes by means of sodium carbonate treatment application to endoplasmic reticulum 

  10. J. Biol. Chem. Georges 268 1792 1993 10.1016/S0021-9258(18)53923-5 Topology of P-glycoprotein as determined by epitope mapping of MRK-16 monoclonal antibody 

  11. Nature Gerlach 324 485 1986 10.1038/324485a0 Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance 

  12. Cell Gilmore 42 497 1985 10.1016/0092-8674(85)90107-2 Translocation of secretory proteins across the microsomal membrane occurs through an environment accessible to aqueous perturbants 

  13. J. Cell Biol. Green 116 597 1992 10.1083/jcb.116.3.597 Mutants in three novel complementation groups inhibit membrane protein insertion into and soluble protein translocation across the endoplasmic reticulum membrane of Saccharomyces cerevisiae 

  14. Cell Gros 47 371 1986 10.1016/0092-8674(86)90594-5 Mammalian multidrug resistance gene 

  15. Mol. Biol. Cell Helenius 5 253 1994 10.1091/mbc.5.3.253 How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum 

  16. J. Cell Biol. High 113 35 1991 10.1083/jcb.113.1.35 The identification of proteins in the proximity of signal-anchor sequences during their targeting to and insertion into the membrane of the ER 

  17. J. Cell Biol. High 121 743 1993 10.1083/jcb.121.4.743 Sec61p is adjacent to nascent type I and type II signal-anchor proteins during their membrane insertion 

  18. EMBO J. Joly 12 255 1993 10.1002/j.1460-2075.1993.tb05651.x The SecA and SecY subunits of translocase are the nearest neighbors of a translocating preprotein, shielding it from phospholipids 

  19. J. Cell Biol. Kalies 126 925 1994 10.1083/jcb.126.4.925 Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p complex 

  20. Biochemistry Kawahara 4 1203 1965 10.1021/bi00883a001 Dissociation of human co-hemoglobin by urea, guanidine hydrochloride, and other reagents 

  21. J. Biol. Chem. Lingappa 253 8667 1978 10.1016/S0021-9258(17)34224-2 A signal sequence for the insertion of a transmembrane glycoprotein 

  22. Nature Ljunggren 346 476 1990 10.1038/346476a0 Empty MHC class I molecules come out in the cold 

  23. J. Biol. Chem. Loo 269 28683 1994 10.1016/S0021-9258(19)61959-9 Prolonged association of temperature-sensitive mutants of human P-glycoprotein with calnexin during biogenesis 

  24. J. Biol. Chem. Machamer 263 5955 1988 10.1016/S0021-9258(18)60659-3 Vesicular stomatitis virus G proteins with altered glycosylation sites display temperature-sensitive intracellular transport and are subject to aberrant intermolecular disulfide bonding 

  25. Cell Martoglio 81 207 1995 10.1016/0092-8674(95)90330-5 The protein-conducting channel in the membrane of the endoplasmic reticulum is open laterally toward the lipid bilayer 

  26. J. Exp. Med. McCune 152 463 1980 10.1084/jem.152.2.463 Biogenesis of membrane-bound and secreted immunoglobulins. I. Two distinct translation products of human μ-chain, with identical N-termini and different C-termini 

  27. Proc. Natl. Acad. Sci. USA McCune 78 5127 1981 10.1073/pnas.78.8.5127 Biogenesis of membrane-bound and secreted immunoglobulins 

  28. J. Mol. Biol. Monro 25 347 1967 10.1016/0022-2836(67)90146-5 Ribosome-catalysed reaction of puromycin with a formylmethionine-containing oligonucleotide 

  29. EMBO J. Mothes 13 3973 1994 10.1002/j.1460-2075.1994.tb06713.x Systematic probing of the environment of a translocating secretory protein during translocation through the ER membrane 

  30. FEBS Lett. Oliver 362 126 1995 10.1016/0014-5793(95)00223-V The Sec61 complex is essential for the insertion of proteins into the membrane of the endoplasmic reticulum 

  31. Science Palade 189 347 1975 10.1126/science.1096303 Intracellular aspects of the process of protein secretion 

  32. Nature Parsegian 221 844 1969 10.1038/221844a0 Energy of an ion crossing a low dielectric membrane 

  33. Proc. Natl. Acad. Sci. USA Redman 56 608 1966 10.1073/pnas.56.2.608 Vectorial discharge of peptides released by puromycin from attached ribosomes 

  34. J. Biol. Chem. Redman 241 1150 1966 10.1016/S0021-9258(18)96815-8 Synthesis and transfer of amylase in pigeon pancreatic microsomes 

  35. J. Cell Biol. Rothblatt 109 2641 1989 10.1083/jcb.109.6.2641 Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast 

  36. J. Biol. Chem. Rothman 263 10470 1988 10.1016/S0021-9258(19)81540-5 Construction of defined polytopic integral transmembrane proteins 

  37. Cell Russel 28 177 1982 10.1016/0092-8674(82)90387-7 Filamentous phage pre-coat is an integral membrane protein 

  38. Cell Simon 65 371 1991 10.1016/0092-8674(91)90455-8 A protein-conducting channel in the endoplasmic reticulum 

  39. Cell Simon 69 677 1992 10.1016/0092-8674(92)90231-Z Signal peptides open protein-conducting channels in E. coli 

  40. Proc. Natl. Acad. Sci. USA Simon 86 6176 1989 10.1073/pnas.86.16.6176 Large aqueous channels in membrane vesicles derived from the rough endoplasmic reticulum of canine pancreas or the plasma membrane of Escherichia coli 

  41. Proc. Natl. Acad. Sci. USA Simon 89 3770 1992 10.1073/pnas.89.9.3770 What drives the translocation of proteins? 

  42. J. Biol. Chem. Skach 268 6903 1993 10.1016/S0021-9258(18)53125-2 Evidence for an alternate model of human P-glycoprotein structure and biogenesis 

  43. Arch. Biochem. Biophys. Skogerson 125 497 1968 10.1016/0003-9861(68)90607-3 Evidence for aminoacyl-tRNA binding, peptide bond synthesis, and translocase activities in the aminoacyl transfer reaction 

  44. J. Supramol. Struct. Steck 1 220 1973 10.1002/jss.400010307 Selective solubilization of proteins from red blood cell membranes by protein perturbants 

  45. Mol. Biol. Cell Stirling 3 129 1992 10.1091/mbc.3.2.129 Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulum 

  46. Adv. Prot. Chem. Tanford 23 121 1968 10.1016/S0065-3233(08)60401-5 Protein denaturation 

  47. Adv. Prot. Chem. Tanford 24 1 1970 10.1016/S0065-3233(08)60241-7 Protein denaturation. C. Theoretical models for the mechanism of denaturation 

  48. J. Cell Biol. Thrift 112 809 1991 10.1083/jcb.112.5.809 A nascent membrane protein is located adjacent to ER membrane proteins throughout its integration and translation 

  49. Annu. Rev. Biophy. Biomol. Struct. Timasheff 22 67 1993 10.1146/annurev.bb.22.060193.000435 The control of protein stability and association by weak interactions with water 

  50. J. Mol. Biol. Traut 10 63 1964 10.1016/S0022-2836(64)80028-0 The puromycin reaction and its relation to protein synthesis 

  51. Eur. J. Biochem. Von Heijne 174 671 1988 10.1111/j.1432-1033.1988.tb14150.x Topogenic signals in internal membrane proteins 

  52. Meth. Enzymol. Walter 96 84 1983 10.1016/S0076-6879(83)96010-X Preparation of microsomal membranes for cotranslational protein translocation 

  53. J. Biol. Chem. Zhang 268 15101 1993 10.1016/S0021-9258(18)82443-7 Membrane topology of the N-terminal half of the hamster P-glycoprotein molecule 

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