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Cell, v.85 no.3, 1996년, pp.415 - 422
Aoufouchi, Said (Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, United Kingdom) , Yélamos, José (Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, United Kingdom) , Milstein, César (Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, United Kingdom)
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AbstractMutations resulting in premature termination codons reduce the corresponding mRNA levels. We describe a cell-free system in which depletion of the mutant immunoglobulin κ mRNA pool correlates with inefficient splicing and not with RNA decay. Splicing deficiency does not depend on the ...
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