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[해외논문] Cell Type–Specific Chromatin Structure Determines the Targeting of V(D)J Recombinase Activity In Vitro 원문보기

Cell, v.85 no.6, 1996년, pp.887 - 897  

Stanhope-Baker, Patricia (Department of Medicine, Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA) ,  Hudson, Karen M (Department of Medicine, Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA) ,  Shaffer, Arthur L (Department of Medicine, Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA) ,  Constantinescu, Andrei (Department of Medicine, Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA) ,  Schlissel, Mark S (Department of Medicine, Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA)

Abstract AI-Helper 아이콘AI-Helper

AbstractA common V(D)J recombinase that recognizes a conserved recombination signal sequence (RSS) mediates the assembly of immunoglobulin (Ig) and T cell receptor (TCR) genes in B and T cell precursors. The rearrangement of particular Ig and TCR gene segments, however, is tightly regulated with res...

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