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[해외논문] Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis 원문보기

Neuron, v.17 no.1, 1996년, pp.9 - 19  

Gale, Nicholas W (Regeneron Pharmaceuticals, Incorporated, 777 Old Saw Mill River Road, Tarrytown, New York, 10591-6707, USA) ,  Holland, Sacha J (Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada,) ,  Valenzuela, David M (Regeneron Pharmaceuticals, Incorporated, 777 Old Saw Mill River Road, Tarrytown, New York, 10591-6707, USA) ,  Flenniken, Ann (Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London, NW7 1AA, United Kingdom,) ,  Pan, Li (Regeneron Pharmaceuticals, Incorporated, 777 Old Saw Mill River Road, Tarrytown, New York, 10591-6707, USA) ,  Ryan, Terrence E (Regeneron Pharmaceuticals, Incorporated, 777 Old Saw Mill River Road, Tarrytown, New York, 10591-6707, USA) ,  Henkemeyer, Mark (Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada,) ,  Strebhardt, Klaus (Chemotherapeutisches Forschungsinstitut, Georg-Speyer-Haus, Paul-Ehrlich Strasse 42-44, 6000, Frankfurt, Federal Republic of Germany,) ,  Hirai, Hisamaru (The Third Department of Internal Medicine, Faculty of Medicine,) ,  Wilkinson, David G ,  Pawson, Tony ,  Davis, Samuel ,  Yancopoulos, George D

Abstract AI-Helper 아이콘AI-Helper

AbstractWe report that the many Eph-related receptor tyrosine kinases, and their numerous membrane-bound ligands, can each be grouped into only two major specificity subclasses. Receptors in a given subclass bind most members of a corresponding ligand subclass. The physiological relevance of these g...

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