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[해외논문] Structure of the FGF Receptor Tyrosine Kinase Domain Reveals a Novel Autoinhibitory Mechanism 원문보기

Cell, v.86 no.4, 1996년, pp.577 - 587  

Mohammadi, Moosa (Department of Pharmacology, New York University Medical Center, New York, New York 10016, USA) ,  Schlessinger, Joseph (Department of Pharmacology, New York University Medical Center, New York, New York 10016, USA) ,  Hubbard, Stevan R (Department of Pharmacology, New York University Medical Center, New York, New York 10016, USA)

Abstract AI-Helper 아이콘AI-Helper

AbstractThe crystal structure of the tyrosine kinase domain of fibroblast growth factor receptor 1 (FGFR1K) has been determined in its unliganded form to 2.0 Å resolution and in complex with an ATP analog to 2.3 Å resolution. Several features distinguish the structure of FGFR1K from th...

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