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[해외논문] Bioavailability of cyclosporine in rats after intragastric administration: a comparative study of the L2-phase and two other lipid-based vehicles

Transplant immunology, v.4 no.4, 1996년, pp.313 - 317  

Bojrup, Malin (Address of correspondence: Malin Bojrup, Camurus AB, Ideon, Gamma 1, Sö) ,  Qi, Zhongquan (lvegatan 41, S-223 70 Lund, Sweden) ,  Björkman, Sven (Department of Experimental Research, Karolinska Institute, Huddinge Hospital, Huddinge Sweden) ,  Östraat, Öyvind (Hospital Pharmacy and Karolinska Institute, Huddinge Hospital, Huddinge Sweden) ,  Landin, Britta (Department of Surgery, Malmö) ,  Ljusberg-Wahren, Helena (University Hospital, Malmö) ,  Ekberg, Henrik (, Karolinska Institute, Huddinge Hospital, Huddinge Sweden)

Abstract AI-Helper 아이콘AI-Helper

AbstractThe purpose of this study was to evaluate formulations based on surface active dietary lipids only as oral vehicles for cyclosporine. The absolute bioavailability of cyclosporine from two new lipid vehicles was determined in rats after intragastric administration and compared to that of Sand...

참고문헌 (30)

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  25. Int J Pharmaceutics Myers 78 217 1992 10.1016/0378-5173(92)90374-B Systemic bioavailability of penclomedine (NSC-338720) fro oil-in-water emulsions administered intraduodenally to rats 

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  27. J Dispers Sci Technol Pilman 3 335 1982 10.1080/01932698208943645 Interfacial tension between an inverse micellar phase of lipid components and aqueous protein solutions 

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  29. Biochemistry Staggers 29 2028 1990 10.1021/bi00460a011 Physical-chemical behavior of dietary and biliary lipids during intestinal digestion and absorption. 1 Phase behavior and aggregation states of model lipid systems patterned after aqueous duodenal contents of healthy adult human beings 

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