다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기
Cell, v.87 no.5, 1996년, pp.917 - 927
Moran, John V (Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA) , Holmes, Susan E (Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA) , Naas, Thierry P (Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA) , DeBerardinis, Ralph J (Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA) , Boeke, Jef D (Department of Molecular Biology and Genetics, The Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA) , Kazazian Jr., Haig H (Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA)
AI-Helper
AbstractWe previously isolated two human L1 elements (L1.2 and LRE2) as the progenitors of disease-producing insertions. Here, we show these elements can actively retrotranspose in cultured mammalian cells. When stably expressed from an episome in HeLa cells, both elements retrotransposed into a var...
J. Mol. Biol. Altschul 215 403 1990 10.1016/S0022-2836(05)80360-2 Basic local alignment search tool
Nucl. Acids Res. Arkhipova 23 4480 1995 10.1093/nar/23.21.4480 Complex patterns of transcription of a Drosophila retrotransposon in vivo and in vitro by RNA polymerases II and III
Science Belfort 262 1009 1993 10.1126/science.7694364 An expanding universe of introns
Curr. Opin. Cell Biol. Boeke 3 502 1991 10.1016/0955-0674(91)90079-E Retrotransposition mechanisms
Cell Boeke 40 491 1985 10.1016/0092-8674(85)90197-7 Ty elements transpose through an RNA intermediate
Cell Bureau 77 479 1994 10.1016/0092-8674(94)90210-0 Transduction of a cellular gene by a plant retroelement
Mol. Cell. Biol. Burke 7 2221 1987 The site-specific ribosomal insertion element type II of Bombyx mori (R2Bm) contains the coding sequence for a reverse transcriptase-like enzyme
J. Mol. Biol. Burton 187 291 1986 10.1016/0022-2836(86)90235-4 Conservation throughout mammalia and extensive protein-encoding capacity of the highly repeated DNA long interspersed sequence one
Proc. Natl. Acad. Sci. USA Conway 82 3949 1985 10.1073/pnas.82.12.3949 A sequence downstream of AAUAAA is required for formation of simian virus 40 late mRNA 3′ termini in frog oocytes
Science Cooley 239 1121 1988 10.1126/science.2830671 Insertional mutagenesis of the Drosophila genome with single P elements
Proc. Natl. Acad. Sci. USA Curcio 88 936 1991 10.1073/pnas.88.3.936 Single-step selection for Ty1 element retrotransposition
Mol. Biol. Evol. Demers 3 179 1986 Long interspersed L1 repeats in rabbit DNA are homologous to L1 repeats of rodents and primates in an open-reading-frame region
Cell Derr 67 355 1991 10.1016/0092-8674(91)90187-4 RNA-mediated recombination in S. cerevisiae
Science Dombroski 254 1805 1991 10.1126/science.1662412 Isolation of an active human transposable element
Mol. Cell. Biol. Dombroski 14 4485 1994 Anin vivo assay for the reverse transcriptase of human retrotransposon L1 in Saccharomyces cerevisiae
Proc. Natl. Acad. Sci. USA Evans 88 8792 1991 10.1073/pnas.88.19.8792 Retrotransposition of a mouse L1 element
Nucl. Acids Res. Fanning 15 2251 1987 10.1093/nar/15.5.2251 The LINE-1 DNA sequences in four mammalian orders predict proteins that conserve homologies to retrovirus proteins
Biochim. Biophys. Acta Fanning 910 203 1987 10.1016/0167-4781(87)90112-6 LINE-1
Cell Feng 87 1996 10.1016/S0092-8674(00)81997-2 Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition
Biotechniques Freeman 17 47 1994 A modified indicator gene for selection of retrotransposition events in mammalian cells
Nature Hattori 321 625 1986 10.1038/321625a0 L1 family of repetitive DNA sequences in primates may be derived from a sequence encoding a reverse transcriptase-related protein
Cell Heidmann 64 159 1991 10.1016/0092-8674(91)90217-M Retrotransposition of a mouse IAP sequence tagged with an indicator gene
Proc. Natl. Acad. Sci. USA Heidmann 85 2219 1988 10.1073/pnas.85.7.2219 An indicator gene to demonstrate intracellular transposition of defective retroviruses
EMBO J. Hohjoh 15 630 1996 10.1002/j.1460-2075.1996.tb00395.x Cytoplasmic ribonucleoprotein complexes containing human LINE-1 protein and RNA
Holmes, S.E. (1994). Characterization of active human L1 elements, Ph.D. Thesis, Johns Hopkins Univ., Baltimore, MD.
J. Biol. Chem. Holmes 267 19765 1992 10.1016/S0021-9258(19)88618-0 Studies on p40, the leucine zipper motif-containing protein encoded by the first open reading frame of an active human LINE-1 transposable element
Nature Genet. Holmes 7 143 1994 10.1038/ng0694-143 A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertion
Hutchison, C.A., III, Hardies, S.C., Loeb, D.D., Shehee, W.R., and Edgell, M.H. (1989). LINES and related retroposons: long interspersed repeated sequences in the eucaryotic genome. In Mobile DNA, D.E. Berg and M.M. Howe eds. (Washington, DC: ASM Press), pp. 593-617.
EMBO J. Jensen 10 1927 1991 10.1002/j.1460-2075.1991.tb07719.x An indicator gene for detection of germline retrotransposition in transgenic Drosophila demonstrates RNA-mediated transposition of the LINE I element
Biochem. Biophys. Res. Commun. Jensen 202 111 1994 10.1006/bbrc.1994.1900 Retrotransposition of the Drosophila LINE I element can induce deletion in target DNA
Proc. Natl. Acad. Sci. USA Katzir 82 1054 1985 10.1073/pnas.82.4.1054 “Retroposon” insertion into the cellular oncogene c-myc in canine transmissible venereal tumor
Nature Kazazian 332 164 1988 10.1038/332164a0 Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man
Nature Genet. Kingsmore 7 136 1994 10.1038/ng0694-136 Glycine receptor β-subunit gene mutation in spastic mouse associated with LINE-1 element insertion
J. Biol. Chem. Kohrman 271 17576 1996 10.1074/jbc.271.29.17576 Mutation detection in the med and medJ alleles of the sodium chanel Scn8a
Methods Enzymol. Kunkel 204 125 1991 10.1016/0076-6879(91)04008-C Efficient site-directed mutagenesis using uracil-containing DNA
Nucl. Acids Res. Kurose 23 3704 1995 10.1093/nar/23.18.3704 RNA polymerase III dependence of the human L1 promoter and possible participation of the RNA polymerase II factor YY1 in the RNA polymerase III transcription system
Proc. Natl. Acad. Sci. USA Leibold 87 6990 1990 10.1073/pnas.87.18.6990 Translation of LINE-1 DNA elements in vitro and in human cells
Mol. Cell. Biol. Luan 15 3882 1995 10.1128/MCB.15.7.3882 RNA template requirements for target DNA-primed reverse transcription by the R2 retrotransposable element
Cell Luan 72 595 1993 10.1016/0092-8674(93)90078-5 Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site
EMBO J. Maestre 14 6333 1995 10.1002/j.1460-2075.1995.tb00324.x mRNA retroposition in human cells
Mol. Cell. Biol. Martin 11 4804 1991 Ribonucleoprotein particles with LINE-1 RNA in mouse embryonal carcinoma cells
Science Mathias 254 1808 1991 10.1126/science.1722352 Reverse transcriptase encoded by a human retrotransposon
Cancer Res. Miki 52 643 1992 Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer
Nucl. Acids Res. Minakami 12 3139 1992 10.1093/nar/20.12.3139 Identification of an internal cis-element essential for the human L1 transcription and a nuclear factor(s) binding to the element
Mol. Cell. Biol. Moran 15 2828 1995 10.1128/MCB.15.5.2828 Mobile group II introns of yeast mitochondrial DNA are novel site-specific retroelements
Nature Morse 333 87 1988 10.1038/333087a0 Insertional mutagenesis of the myc locus by a LINE-1 sequence in a human breast carcinoma
Neuron Mulhardt 13 1003 1994 10.1016/0896-6273(94)90265-8 The spastic mouse
J. Clin. Invest. Narita 91 1862 1993 10.1172/JCI116402 Insertion of a 5′ truncated L1 element into the 3′ end of exon 44 of the dystrophin gene resulted in skipping of the exon during splicing in a case of Duchenne muscular dystrophy
Proc. Natl. Acad. Sci. USA Pelisson 88 4907 1991 10.1073/pnas.88.11.4907 Evidence for retrotransposition of the I factor, a LINE element of Drosophila melanogaster
Sambrook 1989 Molecular Cloning
Genomics Scott 1 113 1987 10.1016/0888-7543(87)90003-6 Origin of the human L1 elements
Gene Singer 135 183 1993 10.1016/0378-1119(93)90064-A LINE-1
Science Swain 255 841 1992 10.1126/science.1371365 Mechanism of transduction by retroviruses
Mol. Cell. Biol. Swergold 10 6718 1990 Identification, characterization, and cell specificity of a human LINE-1 promoter
FEBS Lett. Tanaka 376 146 1995 10.1016/0014-5793(95)01262-2 Unusual long target duplication by insertion of intracisternal A-particle element in radiation-induced acute myeloid leukemia cells in mouse
Hum. Mol. Genet. Takahara 5 989 1996 10.1093/hmg/5.7.989 Dysfunction of the Orleans reeler gene arising from exon skipping due to transposition of a full-length copy of an active L1 sequence into the skipped exon
EMBO J. Tchenio 12 1487 1993 10.1002/j.1460-2075.1993.tb05792.x Generation of processed pseudogenes in murine cells
J. Biol. Chem. Usdin 264 15681 1989 10.1016/S0021-9258(19)84886-X The structure of the guanine-rich polypurine:polypyrimidine sequence at the right end of the rat L1 (LINE) element
Genomics Woods-Samuels 4 290 1989 10.1016/0888-7543(89)90332-7 Characterization of a nondeleterious L1 insertion in an intron of the human factor VIII gene and further evidence of open reading frames in functional L1 elements
EMBO J. Xiong 9 3353 1990 10.1002/j.1460-2075.1990.tb07536.x Origin and evolution of retroelements based upon their reverse transcriptase sequences
Nature Yates 313 812 1985 10.1038/313812a0 Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells
Cell Zimmerly 82 545 1995 10.1016/0092-8674(95)90027-6 Group II intron mobility occurs by target DNA-primed reverse transcription
Cell Zimmerly 83 529 1995 10.1016/0092-8674(95)90092-6 A group II intron RNA is a catalytic component of a DNA endonuclease involved in intron mobility
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
저자가 APC(Article Processing Charge)를 지불한 논문에 한하여 자유로운 이용이 가능한, hybrid 저널에 출판된 논문
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.