[논문]Bloc du plexus brachial : effet de l'addition de sufentanil au mélange d'anesthésiques locaux sur la durée de l'analgésie postopératoire

Bazin, JE; Massoni, C; Groslier, D; Fenies, V; Bittar, M; Schoeffler, P

doi:10.1016/S0750-7658(97)84271-2

[해외논문] Bloc du plexus brachial : effet de l'addition de sufentanil au mélange d'anesthésiques locaux sur la durée de l'analgésie postopératoire
Brachial plexus block: effect of the addition of sufentanil to the mixture of local anaesthetics on duration of post-operative analgesia

Annales françaises d'anesthésie et de réanimation, v.16 no.1, 1997년, pp.9 - 13

Bazin, JE , Massoni, C , Groslier, D , Fenies, V , Bittar, M , Schoeffler, P

Abstract ▼ AI-Helper

AbstractObjectivesTo compare the quality and the duration of analgesia produced by a supraclavicular brachial plexus blockade obtained with a mixture of lidocaine and bupivacaine when supplemented or not with sufentanil.Study designProspective, randomized, double-blind study.PatientsThe study included 40 patients undergoing osteosynthesis of the upper limb under brachial plexus block, randomly assigned to two groups.MethodsThe patients of the control group were given 0.5% bupivacaine 1 mg·kg−1 and 1% lidocaine 2 mg·kg−1. Those of the sufentanil group, received the same mixture supplemented with sufentanil 0,2 mg·kg−1. During the postoperative period, the characteristics of analgesia were blindly evaluated every hour for 48 h with a visual analogic scale graduated from 0 to 100. Analgesia was considered satisfactory when the score was below 30. Adverse effects of opiates (drowsiness, pruritus, nausea and vomiting) were also assessed. Oxygen saturation was continuously monitored. Blood pressure, heart and respiratory rates were measured at the same intervals than analgesia. Duration of analgesia are expressed as medians (range) and compared using a Mann and Whitney's U test.ResultsThe respective durations of satisfactory analgesia were significantly different: 12.5 h (8–17) in the control group versus 24 h (8–48) for the sufentanil group. The adverse effects in the sufentanil group were nausea (2), vomiting (1) and pruritus (1). No respiratory depression was noted.ConclusionSufentanil added to a mixture of lidocaine and bupivacaine increases twofold the duration of postoperative analgesia following brachial plexus blockade.

Abstract

RésuméObjectifsÉtudier les effets sur la durée et la qualité de l'analgésie postopératoire de l'addition de sufentanil à un mélange d'anesthésiques locaux injecté au niveau du plexus brachial, par voie sus-claviculaire.Type d'étudeÉtude prospective, randomisée, en double aveugle.PatientsQuarante patients devant bénéficier d'un bloc du plexus brachial et répartis aléatoirement en deux groupes.RésultatsLes durées d'analgésies satisfaisantes ont été de 12,5 (8–17) h dans le groupe témoin et de 24 (8–48) h dans le groupe sufentanil, la différence étant significative. Les effets secondaires observés dans le groupe sufentanil, ont été des nausées (2), des vomissements (1), du prurit (1). Aucune dépression respiratoire n'a été notée.ConclusionL'addition de sufentanil à un mélange de lidocaïne et de bupivacaïne double la durée d'analgésie obtenue après un bloc du plexus brachial.

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참고문헌 (28)

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DOI : 10.1016/S0750-7658(97)84271-2
Elsevier : 저널 > 논문

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