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[해외논문] A Novel Mutation Avoidance Mechanism Dependent on S. cerevisiae RAD27 Is Distinct from DNA Mismatch Repair 원문보기

Cell, v.88 no.2, 1997년, pp.253 - 263  

Tishkoff, Daniel X. (Charles A. Dana Division of Human Cancer Genetics, Dana–) ,  Filosi, Nicole (Farber Cancer Institute, 44 Binney Street, Department of Biological Chemistry, Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA) ,  Gaida, Gretchen M. (Charles A. Dana Division of Human Cancer Genetics, Dana–) ,  Kolodner, Richard D. (Farber Cancer Institute, 44 Binney Street, Department of Biological Chemistry, Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA)

Abstract AI-Helper 아이콘AI-Helper

AbstractMutations in the S. cerevisiae RAD27 (also called RTH1 or YKL510) gene result in a strong mutator phenotype. In this study we show that the majority of the resulting mutations have a structure in which sequences ranging from 5–108 bp flanked by direct repeats of 3–12 bp are dup...

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