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Effects of L-trans-pyrrolidine-2,4-dicarboxylate, a glutamate uptake inhibitor, on NMDA receptor-mediated calcium influx and extracellular glutamate accumulation in cultured cerebellar granule neurons 원문보기

Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, v.20 no.1, 1997년, pp.7 - 12  

Oh, Seikwan ,  Shin, Chang Sik ,  McCaslin, Patrick P. ,  Seong, Yeon Hee ,  Kim, Hack Seang

Abstract AI-Helper 아이콘AI-Helper

Glutamate uptake inhibitor, L-trans-pyrrolidine-2,4-dicarboxylate (PDC, 20 muM) elevated basal and N-methyl-D-aspartate (NMDA, 100 muM)-induced extracellular glutamate accumulation, while it did not augment kainate (100 muM)-induced glutamate accumulation in cultured cerebellar granule neurons. Howe...

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