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[해외논문] Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex 원문보기

Cell, v.89 no.3, 1997년, pp.357 - 364  

Zhang, Yi (Department of Biochemistry, Howard Hughes Medical Institute, Division of Nucleic Acid Enzymology, University of Medicine and Dentistry of New Jersey, Robert Wood Medical School, Johnson, Piscataway, New Jersey 08854, USA) ,  Iratni, Rabah (Department of Biochemistry, Howard Hughes Medical Institute, Division of Nucleic Acid Enzymology, University of Medicine and Dentistry of New Jersey, Robert Wood Medical School, Johnson, Piscataway, New Jersey 08854, USA) ,  Erdjument-Bromage, Hediye (Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA) ,  Tempst, Paul (Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA) ,  Reinberg, Danny (Department of Biochemistry, Howard Hughes Medical Institute, Division of Nucleic Acid Enzymology, University of Medicine and Dentistry of New Jersey, Robert Wood Medical School, Johnson, Piscataway, New Jersey 08854, USA)

Abstract AI-Helper 아이콘AI-Helper

AbstractAn important event in gene expression is the covalent modification of histone proteins. We have found that the mammalian transcriptional repressor Sin3 (mSin3) exists in a complex with histone deacetylases HDAC1 and HDAC2. Consistent with the observation that mSin3-mediated repression of tra...

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