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Cell, v.90 no.6, 1997년, pp.1097 - 1106
Toczyski, David P. (Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N, C3-167, Seattle, Washington 98109, USA) , Galgoczy, David J. (Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N, C3-167, Seattle, Washington 98109, USA) , Hartwell, Leland H. (Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N, C3-167, Seattle, Washington 98109, USA)
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AbstractA single double-stranded DNA (dsDNA) break will cause yeast cells to arrest in G2/M at the DNA damage checkpoint. If the dsDNA break cannot be repaired, cells will eventually override (that is, adapt to) this checkpoint, even though the damage that elicited the arrest is still present. Here,...
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