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NTIS 바로가기Postgraduate medical journal, v.73 no.864 = no.864, 1997년, pp.617 - 622
Trakatellis, A (Department of Biological Chemistry, Medical School, Aristoteles University of Thessaloniki , Greece) , Dimitriadou, A (Department of Biological Chemistry, Medical School, Aristoteles University of Thessaloniki , Greece) , Trakatelli, M (Department of Biological Chemistry, Medical School, Aristoteles University of Thessaloniki , Greece)
SummaryPyridoxine deficiency leads to impairment of immune responses. It appears that the basic derangement is the decreased rate of production of one-carbon units necessary for the synthesis of nucleic acids. The key factor is a pyridoxine enzyme, serine hydroxymethyltransferase. This enzyme is ver...
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Trakatellis, A.; Axelrod, A.; Montjar, M.; Lamy, F. Induction of immune tolerance with ribosomes and ribonucleic acid extracts in newborn mice Nature 1964 10.1038/202154a0 202 154 Trakatellis A, Axelrod A, Montjar M, Lamy F. Induction of immune tolerance with ribosomes and ribonucleic acid extracts in newborn mice. Nature 1964; 202: 154.
Trakatellis, A.; Axelrod, A. Effect of pyridoxine deficiency on the induction of immune tolerance in mice. Proc Soc Exp Biol Med 1969 132 46 Trakatellis A, Axelrod A. Effect of pyridoxine deficiency on the induction of immune tolerance in mice. Proc Soc Exp Biol Med 1969; 132: 46.
Trakatellis, A.C.; Axelrod, A.E. Effects of pyridoxine deficiency upon valine incorporation into tissue proteins of the rat J Nutr 1964 10.1093/jn/82.4.483 82 483 Trakatellis AC, Axelrod AE. Effects of pyridoxine deficiency upon valine incorporation into tissue proteins of the rat. J Nutr 1964; 82: 483 - 8.
Montiar, M.; Axelrod, A.E.; Trakatellis, A.C. Effect of pyridoxine deficiency upon polysomes and messenger RNA of rat tissues J Nutr 1965 10.1093/jn/85.1.45 85 45 Montiar M, Axelrod AE, Trakatellis AC. Effect of pyridoxine deficiency upon polysomes and messenger RNA of rat tissues. J Nutr 1965; 85: 45-65.
Trakatellis, A.C.; Axelrod, A.E. Effect of pyridoxine deficiency on nucleic acid metabolishm in the rat BiochemJ 1965 10.1042/bj0950344 95 344 Trakatellis AC, Axelrod AE. Effect of pyridoxine deficiency on nucleic acid metabolishm in the rat. BiochemJ 1965; 95: 344-9.
Scountzou, J.; Malissiovas, A.; Antoniadis, A.; Trakatellis, A.C. Inhibitory effect of deoxypyridoxine on the action of certain mitogenic factors Immunopharmacol Immunotoxicol 1989 10.3109/08923978909005393 11 657 Scountzou J, Malissiovas A, Antoniadis A, Trakatellis AC. Inhibitory effect of deoxypyridoxine on the action of certain mitogenic factors. Immunopharmacol Immunotoxicol 1989; 11: 657 - 66.
Trakatellis, A.C.; Dimitriadou, A.; Exindari, M. Effect of pyridoxine deficiency on immunological phenomena Postgrad Med J 1992 68 70 Trakatellis AC, Dimitriadou A, Exindari M, et al. Effect of pyridoxine deficiency on immunological phenomena. Postgrad Med J 1992; 68: 70-7.
Fridas, S.; Trakatellis, A.; Karagouni, E.; Dotsika, E.; Himonas, C.; Conti, P. 4-Deoxypyridoxine inhibits chronic granuloma formation induced by potassium permanganate in vivo Mol Cel Biochem 1994 10.1007/BF00931605 136 59 Fridas S, Trakatellis A, Karagouni E, Dotsika E, Himonas C, Conti P. 4-Deoxypyridoxine inhibits chronic granuloma formation induced by potassium permanganate in vivo. Mol Cel Biochem 1994; 136: 59-63.
Trakatellis, A.; Dimitriadou, A.; Exindari, M. Effect of combination of deoxypyridoxine with known antiproliferative or immmunosuppressive agents on lymphocyte serine hydroxymethyltransferase Postgrad Med J 1994 70 89 Trakatellis A, Dimitriadou A, Exindari M, et al. Effect of combination of deoxypyridoxine with known antiproliferative or immmunosuppressive agents on lymphocyte serine hydroxymethyltransferase. Postgrad Med J 1994; 70: 89-92.
Trakatellis, A.; Exindari, M.; Haitoglou, C.S.; Dimitriadou, A. Serine hydroxymethyltransferase (SHMT) as a precious indicator of antiproliferative or immunosuppressive potency of various compounds Intj Immunopathol Pharmacol 1995 8 31 Trakatellis A, Exindari M, Haitoglou CS, Dimitriadou A. Serine hydroxymethyltransferase (SHMT) as a precious indicator of antiproliferative or immunosuppressive potency of various compounds. Intj Immunopathol Pharmacol 1995; 8: 31-7.
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