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Immunity, v.7 no.5, 1997년, pp.609 - 618
Sharp, Leslie L (The Department of Biology and the Cancer Center, University of California, San Diego, La Jolla, California 92093–) , Schwarz, David A (0687, USA) , Bott, Cynthia M (The Department of Biology and the Cancer Center, University of California, San Diego, La Jolla, California 92093–) , Marshall, Christopher J (0687, USA) , Hedrick, Stephen M (Section of Cell and Molecular Biology, Institute of Cancer Research, Chester Beatty Laboratories, London SW36JB, United Kingdom)
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AbstractDuring development, progenitor thymocytes differentiate into either CD4 or CD8 T cells, and this fate decision depends on the specificity of the T cell antigen receptor (TCR) for MHC class II or class I molecules. Based on the mechanisms of fate specification known for simple metazoan organi...
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