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Immunity, v.7 no.5, 1997년, pp.609 - 618
Sharp, Leslie L (The Department of Biology and the Cancer Center, University of California, San Diego, La Jolla, California 92093–) , Schwarz, David A (0687, USA) , Bott, Cynthia M (The Department of Biology and the Cancer Center, University of California, San Diego, La Jolla, California 92093–) , Marshall, Christopher J (0687, USA) , Hedrick, Stephen M (Section of Cell and Molecular Biology, Institute of Cancer Research, Chester Beatty Laboratories, London SW36JB, United Kingdom)
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AbstractDuring development, progenitor thymocytes differentiate into either CD4 or CD8 T cells, and this fate decision depends on the specificity of the T cell antigen receptor (TCR) for MHC class II or class I molecules. Based on the mechanisms of fate specification known for simple metazoan organi...
Nature Alberola-Ila 373 620 1995 10.1038/373620a0 Selective requirement for MAP kinase activation in thymocyte differentiation
J. Exp. Med Alberola-Ila 184 9 1996 10.1084/jem.184.1.9 Positive and negative selection invoke distinct signaling pathways
J. Biol Chem Alessi 270 27489 1995 10.1074/jbc.270.46.27489 PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
Nature Aroian 348 693 1990 10.1038/348693a0 The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily
Science Artavanis-Tsakonas 268 225 1995 10.1126/science.7716513 Notch signaling
Genes Dev Bailey 9 2609 1995 10.1101/gad.9.21.2609 Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity
Cell Berg 58 1035 1989 10.1016/0092-8674(89)90502-3 Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand
FEBS Lett Bott 352 201 1994 10.1016/0014-5793(94)00958-9 The sevenmaker gain-of-function mutation in p42 MAP kinase leads to enhanced signalling and reduced sensitivity to dual specificity phosphatase action
Cell Brunner 76 875 1994 10.1016/0092-8674(94)90362-X A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways
Semin. Immunol Chan 6 241 1994 10.1006/smim.1994.1031 In favor of the selective model of positive selection
EMBO J Chan 13 4482 1994 10.1002/j.1460-2075.1994.tb06770.x Role of coreceptors in positive selection and lineage commitment
Cold Spring Harbor Symp. Quant. Biol Chang 59 147 1994 10.1101/SQB.1994.059.01.018 Ras signal transduction pathway in Drosophila eye development
Cell Crompton 86 243 1996 10.1016/S0092-8674(00)80096-3 The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte
Curr. Opin. Immunol Davis 6 266 1994 10.1016/0952-7915(94)90100-7 Thymocyte lineage commitment
Cell Davis 73 237 1993 10.1016/0092-8674(93)90226-G Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes
Immunity Dudley 1 83 1994 10.1016/1074-7613(94)90102-3 T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice
Proc. Natl. Acad. Sci. USA Dudley 92 7686 1995 10.1073/pnas.92.17.7686 A synthetic inhibitor of the mitogen-activated protein kinase cascade
Nature Ferguson 326 259 1987 10.1038/326259a0 A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans
Nature Fortini 365 555 1993 10.1038/365555a0 An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye
J. Immunol Godfrey 150 4244 1993 10.4049/jimmunol.150.10.4244 A developmental pathway involving four phenotypically and functionally distinct subsets of CD3−CD4−CD8− triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
Nature Greenwald 346 197 1990 10.1038/346197a0 Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans
Immunol. Today Groettrup 14 610 1993 10.1016/0167-5699(93)90201-U A role for a pre-T-cell receptor in T-cell development
Prog. Neurobiol Hafen 42 287 1994 10.1016/0301-0082(94)90067-1 Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila
Cell Han 63 921 1990 10.1016/0092-8674(90)90495-Z let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein
Blood Hasserjian 88 970 1996 10.1182/blood.V88.3.970.970 Modulated expression of notch1 during thymocyte development
Nature Hill 358 470 1992 10.1038/358470a0 The gene lin-3 encodes an inductive signal for vulval development in C. elegans
Genes Dev Hoffman 10 948 1996 10.1101/gad.10.8.948 Productive T-cell receptor beta-chain gene rearrangement
Cell Howe 71 335 1992 10.1016/0092-8674(92)90361-F Activation of the MAP kinase pathway by the protein kinase raf
J. Exp. Med Itano 183 731 1996 10.1084/jem.183.3.731 The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells
J. Exp. Med Izquierdo 178 1199 1993 10.1084/jem.178.4.1199 p21ras couples the T cell antigen receptor to extracellular signal-regulated kinase 2 in T lymphocytes
Annu. Rev. Immunol Jameson 13 93 1995 10.1146/annurev.iy.13.040195.000521 Positive selection of thymocytes
Cell Katz 82 297 1995 10.1016/0092-8674(95)90317-8 Different levels of the C. elegans growth factor LIN-3 promote distinct vulval precursor fates
Nature Kaye 341 746 1989 10.1038/341746a0 Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor
J. Immunol Kaye 148 3342 1992 10.4049/jimmunol.148.11.3342 Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition
Adv. Immunol Kisielow 58 87 1995 10.1016/S0065-2776(08)60620-3 Development and selection of T cells
Development Koga 121 2655 1995 10.1242/dev.121.8.2655 Mosaic analysis of the let-23 gene function in vulval induction of Caenorhabditis elegans
Nature Kolch 364 249 1993 10.1038/364249a0 Protein kinase C alpha activates RAF-1 by direct phosphorylation
Nature Kyriakis 358 417 1992 10.1038/358417a0 Raf-1 activates MAP kinase-kinase
Genes Dev Lackner 8 160 1994 10.1101/gad.8.2.160 A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans
EMBO J Lake 9 3129 1990 10.1002/j.1460-2075.1990.tb07510.x A 3′ transcriptional enhancer regulates tissue-specific expression of the human CD2 gene
EMBO J Lerner 15 5876 1996 10.1002/j.1460-2075.1996.tb00974.x Cross-linking of T-cell receptors on double-positive thymocytes induces a cytokine-mediated stromal activation process linked to cell death
Oncogene Marquardt 9 3213 1994 Signalling from TPA to MAP kinase requires protein kinase C, raf and MEK
Curr. Opin. Genet. Dev Marshall 4 82 1994 10.1016/0959-437X(94)90095-7 MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
Immunity Matechak 4 337 1996 10.1016/S1074-7613(00)80247-2 MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent
J. Biol. Chem Qiu 269 19480 1994 10.1016/S0021-9258(17)32194-4 Protein kinase C-dependent and -independent pathways of mitogen-activated protein kinase activation in macrophages by stimuli that activate phospholipase A2
J. Immunol Ramsdell 147 1779 1991 10.4049/jimmunol.147.6.1779 The majority of CD4+8− thymocytes are functionally immature
Annu. Rev. Immunol Robey 12 675 1994 10.1146/annurev.iy.12.040194.003331 Selective events in T cell development
Cell Robey 87 483 1996 10.1016/S0092-8674(00)81368-9 An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
Annu. Rev. Cell. Biol Scherer 9 101 1993 10.1146/annurev.cb.09.110193.000533 Superantigens
Cell Sternberg 58 679 1989 10.1016/0092-8674(89)90103-7 The combined action of two intercellular signaling pathways specifies three cell fates during vulval induction in C. elegans
Bioessays Sundaram 18 473 1996 10.1002/bies.950180609 Control and integration of cell signaling pathways during C. elegans vulval development
Nature Surh 372 100 1994 10.1038/372100a0 T-cell apoptosis detected in situ during positive and negative selection in the thymus
EMBO J Swan 14 276 1995 10.1002/j.1460-2075.1995.tb07001.x Involvement of p21ras distinguishes positive and negative selection in thymocytes
Proc. Natl. Acad. Sci. USA Swat 93 4683 1996 10.1073/pnas.93.10.4683 Activated Ras signals differentiation and expansion of CD4+8+ thymocytes
Nature Ward 367 651 1994 10.1038/367651a0 Control of MAP kinase activation by the mitogen-induced threonine/tyrosine phosphatase PAC1
Curr. Opin. Genet. Dev Wassarman 5 44 1995 10.1016/S0959-437X(95)90052-7 The Ras signaling pathway in Drosophila
J. Immunol. Meth Zhumabekov 185 133 1995 10.1016/0022-1759(95)00124-S Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice
Annu. Rev. Neurosci Zipursky 17 373 1994 10.1146/annurev.ne.17.030194.002105 Determination of neuronal cell fate
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