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[해외논문] Extracellular matrix proteins modulate cytochrome P450 2D6 expression in human hepatocytes

Journal of hepatology : the journal of the European Association for the Study of the Liver, v.22 no.1, 1995년, pp.50 - 56  

Trautwein, C. (aAbteilung Gastroenterologie und Hepatologie, Medizinische Hochschule ,, Hannover, Germany) ,  Davies, M. ,  Elias, E. ,  Strain, A. ,  Manns, M.P.

Abstract AI-Helper 아이콘AI-Helper

The role of extracellular matrix proteins on the expression of human liver-specific genes has been investigated. Cytochrome P450 2D6 and albumin are two liver-specific genes which are constitutively expressed in hepatocytes. Primary human hepatocytes were cultured in different extracellular matrix p...

참고문헌 (29)

  1. Annu Rev Biochem Nebert 56 933 1987 10.1146/annurev.bi.56.070187.004501 P450 genes, structure, evolution and regulation 

  2. J Biol Chem Matsunaga 263 17995 1988 10.1016/S0021-9258(19)81314-5 Gene conversion and differential regulation in the rat P-450 IIA gene subfamily 

  3. Int J Biochem Nebert 21 243 1989 10.1016/0020-711X(89)90182-1 Regulation of the mamilian cytochrome P1-450 (CYP1A1) gene 

  4. Mol Cell Biol Yano 12 2847 1992 10.1128/MCB.12.6.2847 Role of the liver enriched transcription factor DBP in expression of the cytochrome P450 CYP2C6 gene 

  5. Nucleic Acid Res Umeno 16 6249 1988 10.1093/nar/16.13.6249 Sequence of the 5′ end of the developmentally regulated rat P450 PB1 (P450IIC6) gene 

  6. Trends Pharmacol Sci Zaphiropoulos 10 149 1989 10.1016/0165-6147(89)90167-3 Regulation of sexual differentiation in drug and steroid metabolism 

  7. Nature Gough 347 773 1990 10.1038/347773a0 Identification of the prime gene defect at the cytochrome P450 CYP2D locus 

  8. J Clin Invest Manns 83 1066 1989 10.1172/JCI113949 Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1 

  9. J Clin Invest Manns 88 1370 1991 10.1172/JCI115443 LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P-450 monooxygenase 

  10. Lancet Michel 339 267 1991 10.1016/0140-6736(92)91332-3 Anti-GOR and hepatitis C virus in autoimmune liver disease 

  11. Biochem Biophys Res Commun Trautwein 182 617 1992 10.1016/0006-291X(92)91777-N Regulation of cytochrome P450 IID by acute phase mediators in C3H/HeJ mice 

  12. J Hepatol Iqbal 12 336 1991 10.1016/0168-8278(91)90837-2 Maintenance of mixed-function and conjugation enzyme activities in hepatocyte cultures prepared from normal and diseased human liver 

  13. J Clin Invest Strain 87 1853 1991 10.1172/JCI115207 Native and recombinant human hepatocyte growth factor are highly potent promoters of DNA synthesis in both human and rat hepatocytes 

  14. Biochemistry Chirgwin 18 5294 1979 10.1021/bi00591a005 Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease 

  15. Z Gastrenterol Trautwein 31 225 1993 Lack of surface expression for the B-cell autoepitope of cytochrome P450 IID6 evidenced by flow cytometry 

  16. J Clin Invest Bissell 79 801 1987 10.1172/JCI112887 Support of cultured hepatocytes by a laminin-rich gel 

  17. In Vitro Strain 18 108 1982 10.1007/BF02796402 Stimulation of DNA synthesis in primary adult hepatocytes by rat platelet associated substances 

  18. J Cell Biol Tarlow 73 332 1977 10.1083/jcb.73.2.332 Lipogenesis and the synthesis and secretion of Very Low Density Lipoprotein by avian liver cells in nonproliferating monolayer culture 

  19. Guillouzo 155 1986 Plasma protein production by cultured adult hepatocytes 

  20. J Cell Biol Isom 105 2877 1987 10.1083/jcb.105.6.2877 Persistence of liver-specific messenger RNA in cultured hepatocytes: different regulatory events for different genes 

  21. J Cell Sci Stamatoglou 97 595 1990 10.1242/jcs.97.4.595 Localization of two fibronectin-binding glycoproteins in rat liver and primary hepatocytes 

  22. J Cell Biol Stamatoglou 111 2117 1990 10.1083/jcb.111.5.2117 Identification of a novel glycoprotein (AGp110) involved in interactions of rat liver parenchymal cells with fibronectin 

  23. Proc Natl Acad Sci Ben-Zeev 85 2161 1988 10.1073/pnas.85.7.2161 Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes 

  24. J Cell Physiol Mooney 151 497 1992 10.1002/jcp.1041510308 Switching from differentiation to growth in hepatocytes: control by extracellular matrix 

  25. Mol Cell Biol Mischoulon 12 2553 1992 10.1128/MCB.12.6.2553 Growth-dependent inhibition of CCAAT enhancer binding protein (C/EBPa) gene expression during hepatocyte proliferation in the regenerating liver and in cell culture 

  26. Genes Dev Cao 5 1538 1991 10.1101/gad.5.9.1538 Regulated expression of the three C/EBP isoforms during adipose conversion of 3T3-L1 cells 

  27. Science Maire 244 343 1989 10.1126/science.2711183 The role of Cis-acting promoter elements in tissue-specific albumin gene expression 

  28. Nature Trautwein 364 544 1993 10.1038/364544a0 Transactivation by LAP/NF-IL6 is enhanced by phosphorylation of its activation domain 

  29. Mol Cell Biol Ueno 10 4495 1990 10.1128/MCB.10.9.4495 Transcriptional control of the rat hepatic CYP2E1 gene 

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