$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

[해외논문] Mice Deficient in Golf Are Anosmic 원문보기

Neuron, v.20 no.1, 1998년, pp.69 - 81  

Belluscio, L. (Department of Biochemistry and Molecular, Biophysics, and Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, , New York 10032,, New York, USA) ,  Gold, G.H. ,  Nemes, A. ,  Axel, R.

Abstract AI-Helper 아이콘AI-Helper

We have used gene targeting to examine the role of the Gα subunit, Golf, in olfactory signal transduction. Mice homozygous for a null mutation in Golf show a striking reduction in the electrophysiological response of primary olfactory sensory neurons to a wide variety of odors. Despite this pr...

참고문헌 (98)

  1. Curr. Opin. Neurobiol Ache 5 461 1995 10.1016/0959-4388(95)80006-9 Dual second-messenger pathways in olfactory transduction 

  2. Gene Adra 60 65 1987 10.1016/0378-1119(87)90214-9 Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter 

  3. Ann. NY Acad. Sci Altar 515 343 1988 10.1111/j.1749-6632.1988.tb33006.x Neostriatal dopamine uptake and reversal of age-related movement disorders with dopamine-uptake inhibitors 

  4. Biochemistry Anholt 29 4049 1990 10.1021/bi00469a004 Olfactory transduction 

  5. Science Bakalyar 250 1403 1990 10.1126/science.2255909 Identification of a specialized adenylyl cyclase that may mediate odorant detection 

  6. Cell Bargmann 74 515 1993 10.1016/0092-8674(93)80053-H Odorant-selective genes and neurons mediate olfaction in C. elegans 

  7. Hum. Mol. Genet Ben-Arie 3 229 1994 10.1093/hmg/3.2.229 Olfactory receptor gene cluster on human chromosome 17 

  8. EMBO J Boekhoff 9 2453 1990 10.1002/j.1460-2075.1990.tb07422.x Rapid activation of alternative second messenger pathways in olfactory cilia from rats by different odorants 

  9. Ciba Found. Symp Breer 179 97 1993 Second messenger signalling in olfaction 

  10. Chem. Senses Breer 16 19 1991 10.1093/chemse/16.1.19 Odorants of the same odor class activate different second messenger pathways 

  11. Nature Breer 345 65 1990 10.1038/345065a0 Rapid kinetics of second messenger formation in olfactory transduction 

  12. Behav. Neurosci Bressler 102 740 1988 10.1037/0735-7044.102.5.740 Changes in electrical activity of rabbit olfactory bulb and cortex to conditioned odor stimulation 

  13. Neuron Brunet 17 681 1996 10.1016/S0896-6273(00)80200-7 General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel 

  14. Curr. Opin. Genet. Dev Buck 2 467 1992 10.1016/S0959-437X(05)80159-5 The olfactory multigene family 

  15. Cell Buck 65 175 1991 10.1016/0092-8674(91)90418-X A novel multigene family may encode odorant receptors 

  16. Genomics Buiakova 20 452 1994 10.1006/geno.1994.1200 Human and rodent OMP genes 

  17. Physiol. Behav Calamandrei 52 901 1992 10.1016/0031-9384(92)90369-D Olfactory recognition of infants in laboratory mice 

  18. Cell Chess 78 823 1994 10.1016/S0092-8674(94)90562-2 Allelic inactivation regulates olfactory receptor gene expression 

  19. Neuron Coburn 17 695 1996 10.1016/S0896-6273(00)80201-9 A putative cyclic nucleotide-gated channel is required for sensory development and function in C. elegans 

  20. J. Neurosci Colbert 17 8259 1997 10.1523/JNEUROSCI.17-21-08259.1997 OSM-9, a novel protein with structural similarity to channels is required for olfaction, mechanosensation, and olfactory adaptation in Caenorhabditis elegans 

  21. Mol. Pharmacol Conklin 50 885 1996 Carboxyl-terminal mutations of Gq alpha and Gs alpha that alter the fidelity of receptor activation 

  22. Physiol. Behav Coppola 56 729 1994 10.1016/0031-9384(94)90234-8 Retronasal or internasal olfaction can mediate odor-guided behaviors in newborn mice 

  23. Nature Dhallan 347 184 1990 10.1038/347184a0 Primary structure and functional expression of a cyclic nucleotide activated channel from olfactory neurons 

  24. Behav. Neurosci Di 99 964 1985 10.1037/0735-7044.99.5.964 Odor-related bulbar EEG spatial pattern analysis during appetitive conditioning in rabbits 

  25. Mol. Cell Neurosci Drinnan 2 66 1991 10.1016/1044-7431(91)90040-U Golf in the basal ganglia 

  26. Science Firestein 244 79 1989 10.1126/science.2704991 Odor-induced membrane currents in vertebrate-olfactory receptor neurons 

  27. Neuron Firestein 6 825 1991 10.1016/0896-6273(91)90178-3 Activation of the sensory current in salamander olfactory receptor neurons depends on a G protein-mediated cAMP second messenger system 

  28. Neuron Friedrich 18 737 1997 10.1016/S0896-6273(00)80314-1 Combinatorial and chemotopic odorant coding in the zebrafish olfactory bulb visualized by optical imaging 

  29. J. Gen. Physiol Frings 97 1 1991 10.1085/jgp.97.1.1 Current recording from the sensory cilia of olfactory receptor cells in situ. I. The neuronal response to cyclic nucleotides 

  30. J. Neurosci Gerfen 15 8167 1995 10.1523/JNEUROSCI.15-12-08167.1995 D1 and D2 dopamine receptor function in the striatum 

  31. Biol. Reprod Griffith 54 761 1996 10.1095/biolreprod54.4.761 Roles of maternal vision and olfaction in suckling-mediated inhibition of luteinizing hormone secretion, expression of maternal selectivity, and lactational performance of beef cows 

  32. Pflügers Arch Hamill 391 85 1981 10.1007/BF00656997 Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches 

  33. Neuroscience Hauber 73 121 1996 10.1016/0306-4522(96)00036-X Impairments of movement initiation and execution induced by a blockade of dopamine D1 or D2 receptors are reversed by a blockade of N-methyl-D-aspartate receptors 

  34. J. Neurosci Herve 13 2237 1993 10.1523/JNEUROSCI.13-05-02237.1993 G(olf) and Gs in rat basal ganglia 

  35. Brain Res. Mol. Brain Res Herve 32 125 1995 10.1016/0169-328X(95)00070-9 Molecular analysis of the multiple Golf alpha subunit mRNAs in the rat brain 

  36. J. Neurophysiol Imamura 68 1986 1992 10.1152/jn.1992.68.6.1986 Coding of odor molecules by mitral/tufted cells in rabbit olfactory bulb. I. Aliphatic compounds 

  37. Nature Joerges 387 285 1997 10.1038/387285a0 Representations of odours and odour mixtures visualized in the honeybee brain 

  38. Chem. Senses Jones 15 333 1990 10.1093/chemse/15.3.333 Distribution of the stimulatory GTP-binding proteins, Gs and Golf, within olfactory epithelium 

  39. J. Biol. Chem Jones 262 14241 1987 10.1016/S0021-9258(18)47929-X Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium 

  40. Science Jones 244 790 1989 10.1126/science.2499043 Golf 

  41. Cold Spring Harb. Symp. Quant. Biol Jones 1 349 1988 10.1101/SQB.1988.053.01.042 Expression of G-protein alpha subunits in rat olfactory neuroepithelium 

  42. The large and small forms of Gs and the olfactory-specific G-protein, Golf. J. Biol. Chem Jones 265 2671 1990 Biochemical characterization of three stimulatory GTP-binding proteins 

  43. J. Neurophysiol Katoh 70 2161 1993 10.1152/jn.1993.70.5.2161 Coding of odor molecules by mitral/tufted cells in rabbit olfactory bulb. II. Aromatic compounds 

  44. Brain. Res Kauer 418 255 1987 10.1016/0006-8993(87)90093-X Odor-elicited activity monitored simultaneously from 124 regions of the salamander olfactory bulb using a voltage-sensitive dye 

  45. Neuroscience Keefe 66 903 1995 10.1016/0306-4522(95)00024-D D1-D2 dopamine receptor synergy in striatum 

  46. J. Exp. Biol Kleene 195 307 1994 10.1242/jeb.195.1.307 An electrophysiological survey of frog olfactory cilia 

  47. Mol. Psychiatry Koob 1 186 1996 Hedonic valence, dopamine and motivation 

  48. J. Physiol. (Lond.) Kurahashi 419 177 1989 10.1113/jphysiol.1989.sp017868 Activation by odorants of cation-selective conductance in the olfactory receptor cell isolated from the newt [published erratum appears in J. Physiol. (Lond.) 424, 561-562] 

  49. Brain Res Kurahashi 515 261 1990 10.1016/0006-8993(90)90605-B Ca2+-dependent adaptive properties in the solitary olfactory receptor cell of the newt 

  50. Nature Kurahashi 385 725 1997 10.1038/385725a0 Mechanism of odorant adaptation in the olfactory receptor cell [see comments] 

  51. Proc. Natl. Acad. Sci. USA Lancet 79 670 1982 10.1073/pnas.79.2.670 Mapping of odor-related neuronal activity in the olfactory bulb by high-resolution 2-deoxyglucose autoradiography 

  52. J. Steroid Biochem. Mol. Biol Levy 39 633 1991 10.1016/0960-0760(91)90262-4 Signal transduction in olfactory neurons 

  53. J. Physiol. (Lond.) Lowe 442 147 1991 10.1113/jphysiol.1991.sp018787 The spatial distributions of odorant sensitivity and odorant-induced currents in salamander olfactory receptor cells 

  54. J. Physiol. (Lond.) Lowe 462 175 1993 10.1113/jphysiol.1993.sp019550 Contribution of the ciliary cyclic nucleotide-gated conductance to olfactory transduction in the salamander 

  55. Nature Lowe 366 283 1993 10.1038/366283a0 Nonlinear amplification by calcium-dependent chloride channels in olfactory receptor cells 

  56. Proc. Natl. Acad. Sci. USA Lowe 86 5641 1989 10.1073/pnas.86.14.5641 Adenylate cyclase mediates olfactory transduction for a wide variety of odorants 

  57. Science Marshall 206 477 1979 10.1126/science.504992 Movement disorders of aged rats 

  58. Ann. NY Acad. Sci Marshall 515 215 1988 10.1111/j.1749-6632.1988.tb32988.x Basal ganglia dopamine receptor autoradiography and age-related movement disorders 

  59. Protein Eng Masters 1 47 1986 10.1093/protein/1.1.47 Family of G protein alpha chains 

  60. Adv. Enzyme. Regul Masters 30 75 1990 10.1016/0065-2571(90)90010-Y Mutational analysis of the structure and function of GTP-binding proteins 

  61. J. Comp. Psychol Mayer 107 12 1993 10.1037/0735-7036.107.1.12 Contributions of olfaction to maternal aggression in laboratory rats (Rattus norvegicus) 

  62. Biol. Reprod Meek 51 400 1994 10.1095/biolreprod51.3.400 Effect of vomeronasal organ removal on behavioral estrus and mating latency in female meadow voles (Microtus pennsylvanicus) 

  63. J. Neurocytol Menco 23 708 1994 10.1007/BF01181645 Developmental expression of G-proteins and adenylyl cyclase in peripheral olfactory systems. Light microscopic and freeze-substitution electron microscopic immunocytochemistry 

  64. Psychoneuroendocrinology Meredith 19 657 1994 10.1016/0306-4530(94)90048-5 Vomeronasal system, LHRH, and sex behaviour 

  65. Nature Miller 334 712 1988 10.1038/334712a0 A mutation that prevents GTP-dependent activation of the alpha chain of Gs 

  66. Cell Mombaerts 87 675 1996 10.1016/S0092-8674(00)81387-2 Visualizing an olfactory sensory map 

  67. Proc. Natl. Acad. Sci. USA Monsma 87 6723 1990 10.1073/pnas.87.17.6723 Molecular cloning and expression of a D1 dopamine receptor linked to adenylyl cyclase activation 

  68. J. Neurophysiol Mori 67 786 1992 10.1152/jn.1992.67.3.786 Differential specificities of single mitral cells in rabbit olfactory bulb for a homologous series of fatty acid odor molecules 

  69. Nature Nakamura 325 442 1987 10.1038/325442a0 A cyclic nucleotide-gated conductance in olfactory receptor cilia 

  70. Biophys. J Nakamura 70 813 1996 10.1016/S0006-3495(96)79625-X Gated conductances in native and reconstituted membranes from frog olfactory cilia 

  71. J. Physiol. (Lond.) Okano 242 353 1974 10.1113/jphysiol.1974.sp010711 Secretion and electrogenesis of the supporting cell in the olfactory epithelium 

  72. Acta Physiol. Scand Ottoson 35 suppl. 1 1956 Analysis of the electrical activity of the olfactory epithelium 

  73. Nature Pace 316 255 1985 10.1038/316255a0 Odorant-sensitive adenylate cyclase may mediate olfactory reception 

  74. Nature Parmentier 355 453 1992 10.1038/355453a0 Expression of members of the putative olfactory receptor gene family in mammalian germ cells 

  75. Neuroendocrinology Rajendren 52 368 1990 10.1159/000125619 Role of the vomeronasal organ in the male-induced enhancement of sexual receptivity in female rats 

  76. Cell Ressler 73 597 1993 10.1016/0092-8674(93)90145-G A zonal organization of odorant receptor gene expression in the olfactory epithelium 

  77. Cell Ressler 79 1245 1994 10.1016/0092-8674(94)90015-9 Information coding in the olfactory system 

  78. Curr. Opin. Neurobiol Ressler 4 588 1994 10.1016/0959-4388(94)90061-2 A molecular dissection of spatial patterning in the olfactory system 

  79. J. Neurobiol Restrepo 30 37 1996 10.1002/(SICI)1097-4695(199605)30:1<37::AID-NEU4>3.0.CO;2-H Second messenger signaling in olfactory transduction 

  80. Neuron Roayaie 20 55 1998 10.1016/S0896-6273(00)80434-1 The Gα protein ODR-3 mediates olfactory and nociceptive function and controls cilium morphogenesis in C. elegans olfactory neurons 

  81. Curr. Opin. Neurobiol Robbins 6 228 1996 10.1016/S0959-4388(96)80077-8 Neurobehavioural mechanisms of reward and motivation 

  82. Physiol. Behav Romeyer 56 693 1994 10.1016/0031-9384(94)90229-1 Olfaction mediates the establishment of selective bonding in goats 

  83. J. Neurosci. Methods Salamone 64 137 1996 10.1016/0165-0270(95)00125-5 The behavioral neurochemistry of motivation 

  84. Histochemistry Schaeren 100 431 1993 10.1007/BF00267823 A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells 

  85. Eur. J. Pharmacol Shiosaki 317 183 1996 10.1016/S0014-2999(96)00718-2 Hyperactivity and behavioral seizures in rodents following treatment with the dopamine D1 receptor agonists A-86929 and ABT-431 

  86. J. Biol. Chem Sklar 261 15538 1986 10.1016/S0021-9258(18)66747-X The odorant-sensitive adenylate cyclase of olfactory receptor cells. Differential stimulation by distinct classes of odorants 

  87. J. Comp. Neurol Stewart 185 715 1979 10.1002/cne.901850407 Functional organization of rat olfactory bulb analysed by the 2-deoxyglucose method 

  88. Proc. Natl. Acad. Sci. USA Sullivan 83 6687 1986 10.1073/pnas.83.18.6687 Inhibitory and stimulatory G proteins of adenylate cyclase 

  89. J. Gen. Physiol Takagi 51 552 1968 10.1085/jgp.51.4.552 The role of sodium and potassium ions in the generation of the electro-olfactogram 

  90. Brain Res Teicher 194 530 1980 10.1016/0006-8993(80)91237-8 Suckling pheromone stimulation of a modified glomerular region in the developing rat olfactory bulb revealed by the 2-deoxyglucose method 

  91. Brain Res Vanderwolf 593 197 1992 10.1016/0006-8993(92)91308-2 Hippocampal activity, olfaction, and sniffing 

  92. Cell Vassar 74 309 1993 10.1016/0092-8674(93)90422-M Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium 

  93. Cell Vassar 79 981 1994 10.1016/0092-8674(94)90029-9 Topographic organization of sensory projections to the olfactory bulb 

  94. J. Neurophysiol Wellis 64 932 1990 10.1152/jn.1990.64.3.932 Intracellular responses of identified rat olfactory bulb interneurons to electrical and odor stimulation 

  95. Development Wilkinson 99 493 1987 10.1242/dev.99.4.493 A molecular analysis of mouse development from 8-10 days post-coitum detects changes only in eukaryotic globin expression 

  96. Cell Xu 79 729 1994 10.1016/0092-8674(94)90557-6 Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses 

  97. Naunyn Schmiedebergs Arch. Pharmacol Zebrowska 297 227 1977 10.1007/BF00509265 Clonidine-induced locomotor hyperactivity in rats. The role of central postsynaptic alpha-adrenoceptors 

  98. Endocrinology Zigman 133 2508 1993 10.1210/endo.133.6.8243272 Human G(olf) alpha 

관련 콘텐츠

오픈액세스(OA) 유형

GOLD(Hybrid)

저자가 APC(Article Processing Charge)를 지불한 논문에 한하여 자유로운 이용이 가능한, hybrid 저널에 출판된 논문

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로