다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기
Cell, v.93 no.4, 1998년, pp.519 - 529
Conradt, Barbara (Department of Biology, Howard Hughes Medical Institute, 68-425, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA) , Horvitz, H.Robert (Department of Biology, Howard Hughes Medical Institute, 68-425, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA)
AI-Helper
AbstractGain-of-function mutations in the Caenorhabditis elegans gene egl-1 cause the HSN neurons to undergo programmed cell death. By contrast, a loss-of-function egl-1 mutation prevents most if not all somatic programmed cell deaths. The egl-1 gene negatively regulates the ced-9 gene, which protec...
Methods Cell Biol. Anderson 48 31 1995 10.1016/S0091-679X(08)61382-5 Mutagenesis
Methods Enzymol. Bai 273 331 1996 10.1016/S0076-6879(96)73029-X Gene identification using the yeast two-hybrid system
Proc. Natl. Acad. Sci. USA Bloom 94 3414 1997 10.1073/pnas.94.7.3414 The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation
Oncogene Boyd 11 1921 1995 Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins
Genetics Brenner 77 71 1974 10.1093/genetics/77.1.71 The genetics of Caenorhabditis elegans
Science Chinnaiyan 275 1122 1997 10.1126/science.275.5303.1122 Interaction of CED-4 with CED-3 and CED-9
Nature Chinnaiyan 388 728 1997 10.1038/41913 Role of CED-4 in the activation of CED-3
EMBO J. Chittenden 14 5589 1995 10.1002/j.1460-2075.1995.tb00246.x A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions
J. Mol. Biol. Coulondre 117 577 1977 10.1016/0022-2836(77)90059-6 Genetic studies of the lac repressor
Genetics DeLong 133 875 1993 10.1093/genetics/133.4.875 Feedback control of sex determination by dosage compensation revealed through Caenorhabditis elegans sdc-3 mutations
Genetics Desai 121 703 1989 10.1093/genetics/121.4.703 Caenorhabditis elegans mutants defective in the functioning of the motor neurons responsible for egg laying
J. Biol. Chem. Diaz 272 11350 1997 10.1074/jbc.272.17.11350 A common binding site mediates heterodimerization and homodimerization of Bcl-2 family members
Cell Ellis 44 817 1986 10.1016/0092-8674(86)90004-8 Genetic control of programmed cell death in the nematode C. elegans
Development Ellis 112 591 1991 10.1242/dev.112.2.591 Two C. elegans genes control the programmed deaths of specific cells in the pharynx
Ann. Rev. Cell Biol. Ellis 7 663 1991 10.1146/annurev.cb.07.110191.003311 Mechanisms and functions of cell death
Genetics Ellis 129 79 1991 10.1093/genetics/129.1.79 Genes required for the engulfment of corpses during programmed cell death in Caenorhabditis elegans
Cell Fraser 85 781 1996 10.1016/S0092-8674(00)81005-3 A license to kill
EMBO J. Hamelin 11 2885 1992 10.1002/j.1460-2075.1992.tb05357.x The mec-7 beta-tubulin gene of Caenorhabditis elegans is expressed primarily in the touch receptor neurons
Mol. Cell. Biol. Han 16 5857 1996 10.1128/MCB.16.10.5857 Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K
Genes Dev. Han 10 461 1996 10.1101/gad.10.4.461 The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein
Nature Hengartner 369 318 1994 10.1038/369318a0 Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2
Cell Hengartner 76 665 1994 10.1016/0092-8674(94)90506-1 C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
Nature Hengartner 356 494 1992 10.1038/356494a0 Caenorhabditis elegans gene ced-9 protects cells from programmed cell death
10.1016/B978-0-12-372180-8.50026-3 Higuchi, R. (1990). Recombinant PCR. In PCR Protocols: A Guide to Methods and Applications, Michael A. Innis, D.H.G., John J. Sninsky, and Thomas J. White, eds. (San Diego: Academic Press), pp. 177-183.
10.1101/SQB.1994.059.01.042 Horvitz, H.R., Shaham, S., and Hengartner, M.O. (1994). The genetics of programmed cell death in the nematode, Caenorhabditis elegans. Cold Spring Harbor Symp. Quant. Biol. LIX, 377-385.
J. Biol. Chem. Hunter 271 8521 1996 10.1074/jbc.271.15.8521 A peptide sequence from Bax that converts Bcl-2 into an activator of apoptosis
Mol. Cell. Biol. Hunter 16 877 1996 10.1128/MCB.16.3.877 Functional dissection of the human Bcl-2 protein
EMBO J. Inohara 16 1686 1997 10.1093/emboj/16.7.1686 Harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-XL
Trends Cell Biol. Jacobson 7 467 1997 10.1016/S0962-8924(97)01182-3 Programmed cell death
Curr. Biol. James 7 246 1997 10.1016/S0960-9822(06)00120-5 CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9
Mol. Cell. Biol. Kelekar 17 7040 1997 10.1128/MCB.17.12.7040 Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-xL
Methods Cell Biol. Mello 48 451 1995 10.1016/S0091-679X(08)61399-0 DNA transformation
Nature Metzstein 328 545 1996 10.1038/382545a0 Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
Nature Muchmore 381 335 1996 10.1038/381335a0 X-ray and NMR structure of human bcl-xL, an inhibitor of programmed cell death
Trends Biochem. Sci. Nicholson 22 299 1997 10.1016/S0968-0004(97)01085-2 Caspases
Development Okkema 120 2175 1994 10.1242/dev.120.8.2175 The Caenorhabditis elegans NK-2 class homeoprotein CEH-22 is involved in combinatorial activation of gene expression in pharyngeal muscle
Cell Death Differ. Ottilie 4 526 1997 10.1038/sj.cdd.4400288 Mutational analysis of the interacting cell death regulators CED-9 and CED-4
J. Biol. Chem. Ottilie 272 30866 1997 10.1074/jbc.272.49.30866 Dimerization properties of human Bad
Nature Raff 356 397 1992 10.1038/356397a0 Social controls on cell survival and cell death
1997 C. elegans II
Curr. Opin. Genet. Dev. Rinkenberger 7 589 1997 10.1016/S0959-437X(97)80004-4 Errors of homeostasis and deregulated apoptosis
1990 Methods in Yeast Genetics
Genetics Ruvkun 121 501 1989 10.1093/genetics/121.3.501 Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14
Sambrook 1989 Molecular Cloning
Science Sattler 275 983 1997 10.1126/science.275.5302.983 Structure of Bcl-xL-Bak peptide complex
Curr. Biol. Seshagiri 7 455 1997 10.1016/S0960-9822(06)00216-8 Caenorhabditis elegans CED-4 stimulates CED-3 processing and CED-3-induced apoptosis
Genes Dev. Shaham 10 578 1996 10.1101/gad.10.5.578 Developing Caenorhabditis elegans neurons may contain both cell death protective and killer activities
Cell Shaham 86 201 1996 10.1016/S0092-8674(00)80092-6 Alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitor
Nature Spector 385 653 1997 10.1038/385653a0 Interactions between the C. elegans cell death regulators CED-9 and CED-4
Dev. Biol. Sulston 56 110 1977 10.1016/0012-1606(77)90158-0 Post-embryonic cell lineages of the nematode Caenorhabditis elegans
Dev. Biol. Sulston 100 64 1983 10.1016/0012-1606(83)90201-4 The embryonic cell lineage of the nematode Caenorhabditis elegans
Genetics Trent 104 619 1983 10.1093/genetics/104.4.619 Egg-laying defective mutants of the nematode Caenorhabditis elegans
Cell Vaux 90 389 1997 10.1016/S0092-8674(00)80497-3 CED-4
Genes Dev. Wang 10 2859 1996 10.1101/gad.10.22.2859 Bid
Genes Dev. White 10 1 1996 10.1101/gad.10.1.1 Life, death, and the pursuit of apoptosis
Genetics Williams 131 609 1992 10.1093/genetics/131.3.609 A genetic mapping system in Caenorhabditis elegans based on polymorphic sequence-tagged sites
Science Wu 275 1126 1997 10.1126/science.275.5303.1126 Interaction and regulation of subcellular localization of CED-4 and CED-9
J. Biol. Chem. Wu 272 21449 1997 10.1074/jbc.272.34.21449 Interaction and regulation of the Caenorhabditis elegans death protease CED-3 by CED-4 and CED-9
Nature Xue 390 305 1997 10.1038/36889 Caenorhabditis elegans CED-9 protein is a bifunctional cell death activator
Cell Yang 80 285 1995 10.1016/0092-8674(95)90411-5 Bad, a heterodimeric partner for Bcl-xL and Bcl-2 displaces Bax and promotes cell death
Nature Yin 369 321 1994 10.1038/369321a0 BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
Development Yuan 116 309 1992 10.1242/dev.116.2.309 The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death
J. Biol. Chem. Zha 271 7440 1996 10.1074/jbc.271.13.7440 Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2
J. Biol. Chem. Zha 272 24101 1997 10.1074/jbc.272.39.24101 BH3 domain of Bad is required for heterodimerization with Bcl-XL and pro-apoptotic activity
Cell Zhou 90 405 1997 10.1016/S0092-8674(00)80501-2 Apaf-1, a human protein homologous to C. elegans CED-4, participates in the cytochrome c-dependent activation of caspase-3
Genes Dev. Zhu 11 2883 1997 10.1101/gad.11.21.2883 end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos
해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
출판사/학술단체 등이 한시적으로 특별한 프로모션 또는 일정기간 경과 후 접근을 허용하여, 출판사/학술단체 등의 사이트에서 이용 가능한 논문
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.