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[해외논문] The effect of anti-CD3-immunotoxin on T lymphocyte function in vitro

Transplant immunology, v.6 no.1, 1998년, pp.53 - 59  

Meng, Gang (University of Alabama at Birmingham, Birmingham, AlabamaU.S.A.) ,  Jiang, Yi (University of Alabama at Birmingham, Birmingham, AlabamaU.S.A.) ,  Hubbard, William (University of Alabama at Birmingham, Birmingham, AlabamaU.S.A.) ,  Thomas, Judith M (Address for correspondence: JM Thomas, Division of Immunology, Department of Surgery, Transplant Center BDB #802, 1808 7th Avenue South, Birmingham, AL, 35294, USA)

Abstract AI-Helper 아이콘AI-Helper

AbstractRecent advances in the design of immunotoxins (IT) have yielded significant improvements. FN18-CRM9, a construct of anti-Cd3ε mAb FN18 and mutated diphtheria toxin CRM9 has exhibited high specificity, low systemic toxicity and unusual efficacy compared to previous iterations of immuno...

참고문헌 (29)

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  20. Immunol Today Wawrzynczak 13 381 1992 10.1016/0167-5699(92)90084-K Immunotoxins: the power and the glory 

  21. Br J Cancer Wu 75 1347 1997 10.1038/bjc.1997.228 Enhancement of immunotoxin activity using chemical and biological reagents [Review] 

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  23. Current Opin Immunol Ghetie 6 707 1994 10.1016/0952-7915(94)90073-6 Recent developments in immunotoxin therapy [Review] 

  24. Transplantation Fechnet 63 1339 1997 10.1097/00007890-199705150-00023 Split tolerance induced by immunotoxin in a rhesus kidney allograft model 

  25. Eur J Immunol Nooij 17 1089 1987 10.1002/eji.1830170803 The effect of skin allograft survival of a monoclonal antibody specific for a polymorphic CD3-like cell surface molecule in rhesus monkeys 

  26. Immunology Nooij 59 611 1986 Polymorphism for RhT3 a CD-3 like cell surface antigen, expressed on rhesus monkey T lymphocytes 

  27. J Immmunol Armitage 150 3671 1993 10.4049/jimmunol.150.9.3671 Human B cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines 

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  29. Proc Natl Acad Sci USA Hancock 93 13967 1996 10.1073/pnas.93.24.13967 Costimulatory function and expression of CD40 ligand, CD80 and CD86 in vascularized murine cardiac allograft rejection 

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