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Macrophage-Derived Nitric Oxide Regulates T Cell Activation via Reversible Disruption of the Jak3/STAT5 Signaling Pathway 원문보기

The journal of immunology : official journal of the American Association of Immunologists, v.160 no.12, 1998년, pp.5729 - 5734  

Bingisser, Roland M. (*TVW Telethon Institute for Child Health Research, Divisions of Cell Biology and Children’s Leukaemia and Cancer Research, West Perth, Australia) ,  Tilbrook, Peta A. (and) ,  Holt, Patrick G. (†Royal Perth Hospital, U.W.A., Department of Biochemistry, Laboratory of Cancer Medicine, Perth, Australia) ,  Kees, Ursula R. (*TVW Telethon Institute for Child Health Research, Divisions of Cell Biology and Children’s Leukaemia and Cancer Research, West Perth, Australia)

Abstract AI-Helper 아이콘AI-Helper

AbstractNitric oxide (NO) has been invoked as an important pathogenic factor in a wide range of immunologically mediated diseases. The present study demonstrates that macrophage-derived NO may conversely function to fine tune T cell-mediated inflammation via reversible dephosphorylation of intracell...

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