$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

[해외논문] Induction of hepatic P-glycoprotein enhances biliary excretion of vincristine in rats

Journal of hepatology : the journal of the European Association for the Study of the Liver, v.23 no.4, 1995년, pp.440 - 448  

Watanabe, T. (Faculty of Pharmaceutical Sciences, University of Tokyo, Hongo) ,  Suzuki, H. (Institute of Molecular and Cellular Biosciences, University of Tokyo, Yayoi) ,  Sawada, Y. (and Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Kami-ikebukuro, Toshima-ku, ,, Tokyo, Japan) ,  Naito, M. ,  Tsuruo, T. ,  Inaba, M. ,  Hanano, M. ,  Sugiyama, Y.

Abstract AI-Helper 아이콘AI-Helper

To clarify the contribution of P-glycoprotein to the biliary excretion of vincristine in rats, the effects of induction of hepatic P-glycoprotein by a phenothiazine treatment on the biliary excretion of [3H]vincristine were investigated. Immunoblot analysis using C219, a monoclonal antibody to P-gly...

참고문헌 (29)

  1. Biochim Biophys Acta Bradley 948 87 1988 Mechanism of multidrug resistance 

  2. Jpn J Cancer Res (Gann) Tsuruo 79 285 1988 10.1111/j.1349-7006.1988.tb01588.x Mechanism of multidrug resistance and implications for therapy 

  3. Adv Cancer Res Van der Bliek 52 165 1989 10.1016/S0065-230X(08)60213-4 Multidrug resistance 

  4. Proc Natl Acad Sci USA Fojo 84 265 1987 10.1073/pnas.84.1.265 Expression of a multidrug-resistance gene in human tumors and tissues 

  5. Proc Natl Acad Sci USA Thiebaut 84 7735 1987 10.1073/pnas.84.21.7735 Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues 

  6. J Histochem Cytochem Thiebaut 37 159 1989 10.1177/37.2.2463300 Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P 170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein 

  7. J Biol Chem Kamimoto 264 11693 1989 10.1016/S0021-9258(18)80120-X The function of Gp170, the multidrug resistance gene product, in rat liver canalicular membrane vesicles 

  8. J Hepatol Watanabe 16 77 1992 10.1016/S0168-8278(05)80098-4 Kinetic analysis of hepatobiliary transport of vincristine in perfused rat liver: possible roles of P-glycoprotein in biliary excretion of vincristine 

  9. J Natl Cancer Inst Burt 80 1383 1988 10.1093/jnci/80.17.1383 Coinduction of MDR-1 multidrug resistance and cytochrome P450 genes in rat liver by xenobiotics 

  10. J Biol Chem Inoue 258 5183 1983 10.1016/S0021-9258(18)32556-0 Rat liver canalicular membrane vesicles 

  11. Biochim Biophys Acta Yachi 901 15 1987 10.1016/0005-2736(87)90251-3 Comparison of bile acid binding to sinusoidal and bile canalicular membranes isolated from rat liver 

  12. Biochim Biophys Acta Yachi 978 1 1989 10.1016/0005-2736(89)90490-2 Characterization of rose bengal binding to sinusoidal and bile canalicular plasma membrane from rat liver 

  13. J Biol Chem Naito 263 11887 1988 10.1016/S0021-9258(18)37869-4 ATP/Mg2+-dependent binding of vincristine to the plasma membrane of multidrug-resistant K562 cells 

  14. Pharmaceut Res Watanabe 6 690 1989 10.1023/A:1015986405834 Saturable process involved in active efflux of vincristine as a mechanism of multidrug resistance in P388 leukemia cells 

  15. Cancer Res Warr 48 4477 1988 Properties of verapamil-hypersensitive multidrug-resistant Chinese hamster ovary cells 

  16. Jpn J Cancer Res Tsuruo 77 682 1986 Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and the isolated clones 

  17. Nature (Lond) Laemmli 227 680 1970 10.1038/227680a0 Cleavage of structural proteins during the assembly of the head of bacteriophage T4 

  18. Proc Natl Acad Sci USA Georges 87 152 1990 10.1073/pnas.87.1.152 Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies 

  19. J Pharmacokinet Biopharm Miyauchi 15 25 1987 10.1007/BF01062937 Kinetics of hepatic transport of 4-methylumbelliferone in rats. Analysis by multiple indicator dilution method 

  20. Proc Natl Acad Sci USA Sato 85 8355 1988 10.1073/pnas.85.21.8355 Dynamic determination of kinetic parameters for the interaction between polypeptide hormones and cell-surface receptors in the perfused rat liver by the multiple indicator dilution method 

  21. J Pharmacokinet Biopharm Tsao 16 165 1988 10.1007/BF01062259 Kinetic analysis of albumin-meditated uptake of warfarin by perfused rat liver 

  22. Pharmaceut Res Nishida 6 140 1989 10.1023/A:1015980525940 Statistical moment analysis of hepatobiliary transport of phenol red in the perfused rat liver 

  23. Anal Biochem Houghton 134 450 1983 10.1016/0003-2697(83)90321-4 Chromatographic analysis of vinca alkaloids in human neoplastic tissues and host (mouse) tissues after injection in vivo or after incubation in vitro 

  24. Cancer Treat Rep Dareer 61 1269 1977 Distribution and metabolism of vincristine in mice, rats, dogs, and monkeys 

  25. Hepatology Arias 12 159 1990 10.1002/hep.1840120125 Multidrug resistance genes, P-glycoprotein and the liver 

  26. Hepatology Schrenk 17 854 1993 10.1002/hep.1840170516 Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates 

  27. J Pharm Sci Wierzba 76 872 1987 10.1002/jps.2600761205 Tubulin as a major determinant of tissue distribution of vincristine 

  28. J Pharm Sci Terasaki 73 1359 1984 10.1002/jps.2600731008 Pharmacokinetic study on the mechanism of tissue distribution of doxorubicin: interorgan and interspecies variation of tissue-to-plasma partition coefficients in rats, rabbits and guinea pigs 

  29. Pharmacol Rev Gonzalez 40 243 1988 The molecular biology of cytochrome P450s 

관련 콘텐츠

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로