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[해외논문] Neurological Illness in Transgenic Mice Expressing a Prion Protein with an Insertional Mutation 원문보기

Neuron, v.21 no.6, 1998년, pp.1339 - 1351  

Chiesa, R. (Department of Cell Biology and, Physiology, Washington University, School of Medicine, , Missouri 63110,, St. Louis, USA) ,  Piccardo, P. ,  Ghetti, B. ,  Harris, D.A.

Abstract AI-Helper 아이콘AI-Helper

Familial prion diseases are caused by mutations in the gene encoding the prion protein (PrP). We have produced transgenic mice that express the mouse homolog of a mutant human PrP containing a nine octapeptide insertion associated with prion dementia. These mice exhibit a slowly progressive neurolog...

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