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[해외논문] Core 2 Oligosaccharide Biosynthesis Distinguishes between Selectin Ligands Essential for Leukocyte Homing and Inflammation 원문보기

Immunity, v.9 no.6, 1998년, pp.881 - 890  

Ellies, Lesley G (Howard Hughes Medical Institute, Division of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California 92093, USA) ,  Tsuboi, Shigeru (The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, California 92037, USA) ,  Petryniak, Bronislawa (Howard Hughes Medical Institute, Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA) ,  Lowe, John B (Howard Hughes Medical Institute, Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA) ,  Fukuda, Minoru (The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, California 92037, USA) ,  Marth, Jamey D (Howard Hughes Medical Institute, Division of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California 92093, USA)

Abstract AI-Helper 아이콘AI-Helper

AbstractMammalian serine/threonine-linked oligosaccharides (O-glycans) are commonly synthesized with the Golgi enzyme core 2 β-1,6-N-acetylglucosaminyltransferase (C2 GlcNAcT). Core 2 O-glycans have been hypothesized to be essential for mucin production and selectin ligand biosynthesis. We re...

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