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Journal of hepatology : the journal of the European Association for the Study of the Liver, v.30 no.3, 1999년, pp.492 - 497
Burczynski, Frank J (Frank J. Burczynski, Faculty of Pharmacy, 50 Sifton Road, University of Manitoba, Winnipeg, Manitoba, Canada, R3T 2N2. Tel: 204 474 6902. Fax: 204 474 7617.) , Wang, GuQi (Faculty of Pharmacy, Departments of Pharmacology and Medicine, University of Manitoba, Winnipeg, Manitoba, Canada) , Minuk, Gerry Y (Liver Diseases Unit, Departments of Pharmacology and Medicine, University of Manitoba, Winnipeg, Manitoba, Canada) , Rosser, Barry (Liver Diseases Unit, Departments of Pharmacology and Medicine, University of Manitoba, Winnipeg, Manitoba, Canada)
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AbstractBackground/Aims: Although cirrhosis is known to be associated with many hepatocyte abnormalities, there is no well-established model to study the cellular drug uptake process independent of hemodynamic effects. The purpose of the present study was to test the following hypothesis: hepatocyte...
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