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[해외논문] NMDAR Channel Segments Forming the Extracellular Vestibule Inferred from the Accessibility of Substituted Cysteines

Neuron, v.22 no.3, 1999년, pp.559 - 570  

Beck, C (Abteilung Molekulare Neurobiologie, Max-Planck-Institut fü) ,  Wollmuth, L.P (r medizinische Forschung, Jahnstrasse 29, D-69120 Heidelberg, Germany) ,  Seeburg, P.H (Abteilung Zellphysiologie, Max-Planck-Institut fü) ,  Sakmann, B (r medizinische Forschung, Jahnstrasse 29, D-69120 Heidelberg, Germany) ,  Kuner, T (Abteilung Molekulare Neurobiologie, Max-Planck-Institut fü)

Abstract AI-Helper 아이콘AI-Helper

AbstractIn NMDA receptor channels, the M2 loop forms the narrow constriction and the cytoplasmic vestibule. The identity of an extracellular vestibule leading toward the constriction remained unresolved. Using the substituted cysteine accessibility method (SCAM), we identified channel-lining residue...

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