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Neurochemistry international, v.36 no.2, 2000년, pp.97 - 112
Gibson, Gary E (Corresponding author. Tel.: +914-597-2291) , Park, Larry C.H (fax: +914-597-2757) , Sheu, Kwan-Fu Rex (Department of Neurology and Neuroscience, Weill Medical College of Cornell University, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA) , Blass, John P (Department of Neurology and Neuroscience, Weill Medical College of Cornell University, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA) , Calingasan, Noel Y (Department of Neurology and Neuroscience, Weill Medical College of Cornell University, Burke Medical Research Institute, 785 Mamaroneck Avenue, White Plains, NY 10605, USA)
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AbstractAltered energy metabolism is characteristic of many neurodegenerative disorders. Reductions in the key mitochondrial enzyme complex, the α-ketoglutarate dehydrogenase complex (KGDHC), occur in a number of neurodegenerative disorders including Alzheimer’s Disease (AD). The reduc...
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