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[해외논문] Drosophila p53 Is a Structural and Functional Homolog of the Tumor Suppressor p53 원문보기

Cell, v.101 no.1, 2000년, pp.91 - 101  

Ollmann, Michael (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) ,  Young, Lynn M (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) ,  Di Como, Charles J (Department of Biological Sciences, Columbia University, New York, New York 10027, USA) ,  Karim, Felix (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) ,  Belvin, Marcia (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) ,  Robertson, Stephanie (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) ,  Whittaker, Kellie (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) ,  Demsky, Madelyn (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) ,  Fisher, William W (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) ,  Buchman, Andrew (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) ,  Duyk, Geoffrey (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) ,  Friedman, Lori (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, C) ,  Prives, Carol ,  Kopczynski, Casey

Abstract AI-Helper 아이콘AI-Helper

Abstract The importance of p53 in carcinogenesis stems from its central role in inducing cell cycle arrest or apoptosis in response to cellular stresses. We have identified a Drosophila homolog of p53 (“Dmp53”). Like mammalian p53, Dmp53 binds specifically to human p53 binding si...

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