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Cell, v.101 no.1, 2000년, pp.91 - 101
Ollmann, Michael (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) , Young, Lynn M (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) , Di Como, Charles J (Department of Biological Sciences, Columbia University, New York, New York 10027, USA) , Karim, Felix (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) , Belvin, Marcia (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) , Robertson, Stephanie (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) , Whittaker, Kellie (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) , Demsky, Madelyn (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) , Fisher, William W (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) , Buchman, Andrew (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) , Duyk, Geoffrey (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, California 94080, USA) , Friedman, Lori (Exelixis, Inc., 260 Littlefield Avenue, South San Francisco, C) , Prives, Carol , Kopczynski, Casey
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Abstract The importance of p53 in carcinogenesis stems from its central role in inducing cell cycle arrest or apoptosis in response to cellular stresses. We have identified a Drosophila homolog of p53 (“Dmp53”). Like mammalian p53, Dmp53 binds specifically to human p53 binding si...
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