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[해외논문] A Genetic Analysis of Synaptic Development : Pre- and Postsynaptic dCBP Control Transmitter Release at the Drosophila NMJ 원문보기

Neuron, v.25 no.3, 2000년, pp.537 - 547  

Marek, Kurt W. (Department of Biochemistry and Biophysics, Programs in Cell Biology and Neuroscience, University of California Medical School, San Francisco, California 94143, USA) ,  Ng, Norman (Department of Biochemistry and Biophysics, Programs in Cell Biology and Neuroscience, University of California Medical School, San Francisco, California 94143, USA) ,  Fetter, Richard (Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, California 94720, USA) ,  Smolik, Sarah (Department of Cell and Developmental Biology, Oregon Health Science University, Portland, Oregon 97201, USA) ,  Goodman, Corey S. (Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, California 94720, USA) ,  Davis, Graeme W. (Department of Biochemistry and Biophysics, Programs in Cell Biology and Neuroscience, University of California Medical School, San Francisco, California 94143, USA)

Abstract AI-Helper 아이콘AI-Helper

AbstractPostsynaptic dCBP (Drosophila homolog of the CREB binding protein) is required for presynaptic functional development. Viable, hypomorphic dCBP mutations have a ∼50% reduction in presynaptic transmitter release without altering the Ca2+ cooperativity of release or synaptic ultrastruct...

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