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[해외논문] HCV-core protein accelerates recovery from the insensitivity of liver cells to Fas-mediated apoptosis induced by an injection of anti-Fas antibody in mice

Journal of hepatology : the journal of the European Association for the Study of the Liver, v.33 no.3, 2000년, pp.440 - 447  

Honda, Arata (First Department of Medicine, Chiba University School of Medicine, Chiba,Japan) ,  Hatano, Masahiko (>) ,  Kohara, Michinori (Department of Developmental Genetics, Chiba University Graduate School of Medicine, Chiba,Japan) ,  Arai, Yutaka (Department of Microbiology, The Tokyo Metropolitan Institute of Medical Science,Tokyo,Japan) ,  Hartatik, Tety (>) ,  Moriyama, Takashi (Department of Developmental Genetics, Chiba University Graduate School of Medicine, Chiba,Japan) ,  Imawari, Michio (>) ,  Koike, Katsuro (Department of Developmental Genetics, Chiba University Graduate School of Medicine, Chiba,Japan) ,  Yokosuka, Osamu (Division of Molecular Immunology, Jichi Medical School, Tochigi,Japan) ,  Shimotohno, Kunitada (Omiya Medical Center, Jichi Medical School, Saitama,Japan) ,  Tokuhisa, Takeshi (Department of Gene Research, Cancer Institute, JFCR, Tokyo,Japan)

Abstract AI-Helper 아이콘AI-Helper

AbstractBackground/Aims: Hepatitis C virus (HCV) is a major etiologic agent of chronic hepatitis, cirrhosis, and hepatocellular carcinoma. The aim of this study was to elucidate pathological effects of HCV-core protein on liver cells.Methods: We have generated transgenic mice carrying HCV-core cDNA ...

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