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[해외논문] The flavonoid quercetin ameliorates liver damage in rats with biliary obstruction

Journal of hepatology : the journal of the European Association for the Study of the Liver, v.33 no.5, 2000년, pp.742 - 750  

Peres, William (Department of Physiology University of Leó) ,  Tuñón, María J (n Leó) ,  Collado, Pilar S (n, Spain) ,  Herrmann, Stela (Department of Physiology University of Leó) ,  Marroni, Norma (n Leó) ,  González-Gallego, Javier (n, Spain)

Abstract AI-Helper 아이콘AI-Helper

AbstractBackground/Aims: Our aim was to investigate whether the antioxidant quercetin might protect against liver injury in chronically biliary obstructed rats.Methods: Secondary biliary cirrhosis was induced by 28 days of bile duct obstruction. Animals received quercetin at 75, 150 and 300 μ...

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참고문헌 (52)

  1. Aust N J Surg Hunt 50 476 1980 10.1111/j.1445-2197.1980.tb04173.x The identification of risk factors and their application to the management of obstructive jaundice 

  2. Sokol 75 1992 Pediatric Cholestasis Dordrecht Kluwer Lipid peroxidation in cholestasis 

  3. Clin Chim Acta Tasi 215 41 1993 10.1016/0009-8981(93)90247-2 Changes of lipid levels in blood and liver tissues of patients with obstructive jaundice 

  4. Gastroenterology Singh 103 1625 1992 10.1016/0016-5085(92)91187-9 Antioxidant defenses in the bile duct-hgated rat 

  5. Hepatology Krahenbuhl 22 607 1995 Reduced antioxidative capacity in liver mitochondria from bile duct ligated rats 

  6. Hepatology Forestier 26 386 1997 10.1002/hep.510260219 Hepatic mitochondrial pioliferation in rats with secondary biliary cirrhosis time courses and mechanisms 

  7. J Hepatol Muriel 21 95 1994 10.1016/S0168-8278(94)80143-6 Protective effect of S-adenosylmethionine on liver damage induced by biliary obstruction in rats a histological, ultrastructural and biochemical study 

  8. Hepatology Gonzalez-Correa 26 121 1997 Effects of S-adenosyl-L-methionine on hepatic and renal oxidative stress in an experimental model of acute biliary obstruction in rats 

  9. J Hepatol Pastor 24 353 1996 10.1016/S0168-8278(96)80016-X Microsomal function in biliary obstructed rats effects of S-adenosylmethionine 

  10. J Hepatol Pastor 27 363 1997 10.1016/S0168-8278(97)80183-3 Antioxidant enzyme status in biliary-obstructed rats effects of N-acetylcysteine 

  11. Clin Chim Acta Pace-Asciak 235 207 1995 10.1016/0009-8981(95)06045-1 The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation in eicosanoid synthesis implication for protection against coronary heart disease 

  12. Science Jang 275 218 1997 10.1126/science.275.5297.218 Cancer chemopreventive activity of resveratrol, a natural product derived from grapes 

  13. Jovanovic 137 1998 Flavonoids in Health and Disease Antioxidant properties of flavonoids reduction potentials and electron transfer reactions of flavonoid radicals 

  14. Hepatology Kawada 27 1265 1998 10.1002/hep.510270512 Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells 

  15. Br J Surg Huk 85 1080 1998 10.1046/j.1365-2168.1998.00787.x Bioflavonoid quercetin scavenges superoxide and increases nitric oxide concentration in ischaemia-reperfusion injury an experimental study 

  16. National Institutes of Health 1991 National Academy of Sciences The Guiding Principles for Research Involving Animals Bethesda, MD 

  17. J Biol Chem Lowry 193 265 1951 10.1016/S0021-9258(19)52451-6 Protein measurement with the Pholin phenol reagent 

  18. Anal Biochem Hissin 74 214 1976 10.1016/0003-2697(76)90326-2 A fluorimetric method for determination of oxidised and reduced glutathione in tissues 

  19. J Biol Chem Misra 247 3170 1972 10.1016/S0021-9258(19)45228-9 The role of superoxide anion in the autooxidation of epinephrine and a simple assay for superoxide dismutase 

  20. Aebi 273 1983 Methods of Enzymatic Analysis, Vol 3 Catalase 

  21. Methods Enzymol Flohe 105 115 1984 Glutathione peroxidase 

  22. Anal Biochem Ohkawa 95 351 1979 10.1016/0003-2697(79)90738-3 Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction 

  23. Hepatology Aguilar-Delfin 24 657 1996 10.1002/hep.510240331 Selective enhancement of lipid peroxidation in plasma membrane in two experimental models of liver regeneration partial hepatectomy and acute CCl4 administration 

  24. Kidney Int Cattell 38 1056 1990 10.1038/ki.1990.312 Glomeruli synthetise nitrite in experimental nephrotoxic nephritis 

  25. Anal Biochem Rojkind 57 1 1974 10.1016/0003-2697(74)90043-8 An improved method for determining specific radioactivities of proline 14C and hydroxyproline 14C in collagen and non-collagenous proteins 

  26. J Hepatol Aleynik 27 554 1997 10.1016/S0168-8278(97)80361-3 Polyenyl-phosphatidylcholine prevents carbon tetrachloride-induced lipid peroxidation while it attenuates liver fibrosis 

  27. Ames Iowa State University Snedecor 185 1980 Statistical Methods 

  28. Free Radical Biol Med Parola 20 351 1996 10.1016/0891-5849(96)02055-2 On the role of lipid peroxidation in the pathogenesis of liver damage induced by long-standing cholestasis 

  29. J Hepatol Gasso 25 200 1996 10.1016/S0168-8278(96)80074-2 Effects of S-adenosylmethionine on lipid peroxidation and liver fibrogenesis in carbon tetrachloride-induced cirrhosis 

  30. Hepatology Saperstein 19 412 1994 10.1002/hep.1840190220 Transforming growth factor-β1 and mannose 6-phosphate/insulin like growth factor-II receptor expression during intrahepatic bile duct hyperplasia and biliary fibrosis in the rat 

  31. J Clin Invest Lee 96 2461 1995 10.1172/JCI118304 Activation of hepatic stellate cells by TGFα and collagen type I is mediated by oxidative stress trough c-myb expression 

  32. Free Radical Biol Med Poli 22 287 1997 10.1016/S0891-5849(96)00327-9 Oxidative damage and fibrogenesis 

  33. Hepatology Nagi 28 423 1998 10.1002/hep.510280220 Dexamethasone inhibits the proliferation of hepatocytes and oval cells but not bile duct cells in rat liver 

  34. FASEB J Leonarduzzi 11 851 1997 10.1096/fasebj.11.11.9285483 The lipid peroxidation end-product 4-hydroxy-2,3-nonenal up-regulates transforming growth factor betal expression in the macrophage lineage a link between oxidative injury and fibrosclerosis 

  35. Clin Sci Camps 83 695 1992 10.1042/cs0830695 Relationship between hepatic lipid peroxidation and fibrogenesis in carbon tetrachloride-treated rats effect of zinc administration 

  36. Hepatology Bedossa 19 1262 1994 Stimulation of collagen α(I) gene expression is associated with lipid peroxidation in hepatocellular injury a link to tissue fibrosis? 

  37. Hepatology Corrales 16 1022 1992 10.1002/hep.1840160427 S-adenosylmethionine treatment prevents carbon tetrachloride-induced S-adenosylmethionine synthetase inactivation and attenuates liver injury 

  38. FASEB J Sanchez-Gongora 11 1013 1997 10.1096/fasebj.11.12.9337154 Interaction of liver methionine adenosyltransferase with hydroxyl radical 

  39. Hepatology Ruiz 28 1051 1998 10.1002/hep.510280420 Nitric oxide inactivates rat hepatic methionine adenosyltransferase in vivo by Snitrosylation 

  40. Clin Sci Mayoral 96 297 1999 10.1042/CS19980250 Effects of chronic nitric oxide activation or inhibition on early hepatic fibrosis in rats with bile duct ligation 

  41. Biochem Pharmacol Cheis 49 495 1995 10.1016/0006-2952(94)00433-M Inhibition of constitutive endothelial NO-synthase activity by tannin and quercetin 

  42. Gastroenterology Castilla-Cortazar 113 1682 1997 10.1053/gast.1997.v113.pm9352873 Hepatoprotective effect of insulin-like growth factor I in rats with carbon tetrachloride-induced cirrhosis 

  43. Biochemistry Hodgson 14 5294 1975 10.1021/bi00695a010 The interaction of bovine erythrocyte superoxide dismutase with hydrogen peroxide inactivation of the enzyme 

  44. Arch Biochem Biophys Blum 240 500 1985 10.1016/0003-9861(85)90056-6 Inactivation of glutathione peroxidase by superoxide radical 

  45. Free Radical Med Biol Kinter 21 457 1996 10.1016/0891-5849(96)00128-1 Glutathione consumption and glutathione peroxidase inactivation in fibroblast cell lines by 4-hydroxy-2-nonenal 

  46. Arch Biochem Biophys Ji 263 150 1988 10.1016/0003-9861(88)90623-6 Antioxidant enzyme systems in rat liver and skeletal muscle Influences of selenium deficiency, chronic training and acute exercise 

  47. Hepatology Polavarapu 27 1317 1998 10.1002/hep.510270518 Increased lipid peroxidation and impaired antioxidant enzyme function is associated with pathological liver injury in experimental alcoholic liver disease in rats fed diets high in corn oil and fish oil 

  48. J Hepatol Swart 31 1034 1999 10.1016/S0168-8278(99)80316-X Targeting of superoxide dismutase to the liver results in antrinflammatory effects in rats with fibrotic livers 

  49. Free Radical Biol Med Cao 22 749 1997 10.1016/S0891-5849(96)00351-6 Antioxidant and prooxidant behavior of flavonoids structure-activity relationships 

  50. Food Chem Toxic Formica 33 1061 1995 10.1016/0278-6915(95)00077-1 Review of the biology of quercetin and related bioflavonoids 

  51. Carcinogenesis Ahmad 13 605 1992 10.1093/carcin/13.4.605 Activities of flavonoids for the cleavage of DNA in the presence of Cu(II) correlation with geneiation of active oxygen species 

  52. Biochem Pharmacol Hodnick 47 573 1994 10.1016/0006-2952(94)90190-2 Inhibition of mitochondrial iespiration and cyanide-stimulated generation of reactive oxygen species by selected flavonoids 

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