[논문]Bradykinin regulation of salt transport across mouse inner medullary collecting duct epithelium involves activation of a Ca2+‐dependent Cl− conductance

Kose, H; Boese, S H; Glanville, M; Gray, M A; Brown, C D A; Simmons, N L

doi:10.1038/sj.bjp.0703749

[해외논문] Bradykinin regulation of salt transport across mouse inner medullary collecting duct epithelium involves activation of a Ca2+‐dependent Cl− conductance 원문보기

British journal of pharmacology : BJP, v.131 no.8, 2000년, pp.1689 - 1699

Kose, H , Boese, S H , Glanville, M , Gray, M A , Brown, C D A , Simmons, N L

Abstract ▼ AI-Helper

The mechanism by which bradykinin regulates renal epithelial salt transport has been investigated using a mouse inner medullary renal collecting duct cell‐line mIMCD‐K2.Using fura‐2 loaded mIMCD‐K2 cells bradykinin (100 nM) has been shown to induce a transient increase in intracellular Ca2+via activation of bradykinin B2 receptors localized to both the apical and basolateral epithelial cell surfaces.In mIMCD‐K2 epithelial cell‐layers clamped in Ussing chambers, 100 nM bradykinin via apical and basolateral bradykinin B2 receptors stimulated a transient increase in inward short‐circuit current (Isc) of similar duration to the increase in intracellular Ca2+.Replacements of the bathing solution Na+ by the impermeant cation, N‐methyl‐D‐glucamine and of Cl− and HCO3− by the impermeant anion gluconate at either the apical (no reduction) or basal bathing solutions (abolition of the response) are consistent with the bradykinin‐stimulated increase in inward Isc resulting from basal to apical Cl− (anion) secretion.Using the slow whole cell configuration of the patch‐clamp technique, bradykinin was shown to activate a transient Cl− selective whole cell current which showed time‐dependent activation at positive membrane potentials and time‐dependent inactivation at negative membrane potentials. These currents were distinct from those activated by forskolin (CFTR), but identical to those activated by exogenous ATP and are therefore consistent with bradykinin activation of a Ca2+‐dependent Cl− conductance.The molecular identity of the Ca2+‐dependent Cl− conductance has been investigated by an RT-PCR approach. Expression of an mRNA transcript with 96% identity to mCLCA1/2 was confirmed, however an additional but distinct mRNA transcript with only 81% of the identity to mCLCA1/2 was identified.British Journal of Pharmacology (2000) 131, 1689-1699; doi:10.1038/sj.bjp.0703749

참고문헌 (45)

10.1093/nar/25.17.3389
Agnel, Magali, Vermat, Thierry, Culouscou, Jean-Michel. Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea. FEBS letters, vol.455, no.3, 295-301.

상세보기
Attwood, T K, Flower, D R, Lewis, A P, Mabey, J E, Morgan, S R, Scordis, P, Selley, J N, Wright, W. PRINTS prepares for the new millennium.. Nucleic acids research, vol.27, no.1, 220-225.

상세보기
Boese, S. H., Glanville, M., Aziz, O., Gray, M. A., Simmons, N. L.. Ca²⁺ and cAMP‐activated Cl⁻ conductances mediate Cl⁻ secretion in a mouse renal inner medullary collecting duct cell line. The Journal of physiology, vol.523, no.2, 325-338.

상세보기
Chao, Julie, Chao, Lee. Functional Analysis of Human Tissue Kallikrein in Transgenic Mouse Models. Hypertension, vol.27, no.3, 491-494.

상세보기
10.1093/nar/16.22.10881
Cunningham, Sonia A., Awayda, Mouhamed S., Bubien, James K., Ismailov, Iskander I., Arrate, M. Pia, Berdiev, Bakhram K., Benos, Dale J., Fuller, Catherine M.. Cloning of an Epithelial Chloride Channel from Bovine Trachea. The Journal of biological chemistry, vol.270, no.52, 31016-31026.

상세보기
Am. J. Physiol. CUTHBERT A.W. F439 249 1985 Kinin effects on electrogenic ion transport in primary cultures of pig renal papillary collecting duct cells
Evans, M G, Marty, A. Calcium‐dependent chloride currents in isolated cells from rat lacrimal glands.. The Journal of physiology, vol.378, 437-460.

상세보기
Figueroa, C D, Gonzalez, C B, Grigoriev, S, Abd Alla, S A, Haasemann, M, Jarnagin, K, Müller-Esterl, W. Probing for the bradykinin B2 receptor in rat kidney by anti-peptide and anti-ligand antibodies.. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, vol.43, no.2, 137-148.

상세보기
Gainer, James V., Morrow, Jason D., Loveland, Angela, King, Debbie J., Brown, Nancy J.. Effect of Bradykinin-Receptor Blockade on the Response to Angiotensin-Converting-Enzyme Inhibitor in Normotensive and Hypertensive Subjects. The New England journal of medicine, vol.339, no.18, 1285-1292.

상세보기
Gandhi, R., Elble, R.C., Gruber, A.D., Schreur, K.D., Ji, H.-L., Fuller, C.M., Pauli, B.U.. Molecular and Functional Characterization of a Calcium-sensitive Chloride Channel from Mouse Lung. The Journal of biological chemistry, vol.273, no.48, 32096-32101.

상세보기
Gray, M. A., Winpenny, J. P., Porteous, D. J., Dorin, J. R., Argent, B. E.. CFTR and calcium-activated chloride currents in pancreatic duct cells of a transgenic CF mouse. American journal of physiology. Cell physiology, vol.266, no.1, C213-C221.

상세보기
Am. J. Physiol. GREEN R.B. F1248 271 1996 Hyperosmolarity inhibits sodium absorption and chloride secretion in mIMCD‐K2 cells
Gruber, Achim D., Elble, Randolph C., Ji, Hong-Long, Schreur, Kevin D., Fuller, Catherine M., Pauli, Bendicht U.. Genomic Cloning, Molecular Characterization, and Functional Analysis of Human CLCA1, the First Human Member of the Family of Ca²⁺-Activated Cl⁻Channel Proteins. Genomics, vol.54, no.2, 200-214.

상세보기
Gruber, Achim D., Gandhi, Renu, Pauli, B. U.. The murine calcium-sensitive chloride channel (mCaCC) is widely expressed in secretory epithelia and in other select tissues. Histochemistry and cell biology, vol.110, no.1, 43-49.

상세보기
Gruber, Achim D., Schreur, Kevin D., Ji, Hong-Long, Fuller, Catherine M., Pauli, Bendicht U.. Molecular cloning and transmembrane structure of hCLCA2 from human lung, trachea, and mammary gland. American journal of physiology. Cell physiology, vol.276, no.6, C1261-C1270.

상세보기
Grynkiewicz, G, Poenie, M, Tsien, R Y. A new generation of Ca2+ indicators with greatly improved fluorescence properties.. The Journal of biological chemistry, vol.260, no.6, 3440-3450.

상세보기
Hamill, O. P., Marty, A., Neher, E., Sakmann, B., Sigworth, F. J.. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers archiv : European journal of physiology, vol.391, no.2, 85-100.

상세보기
Hume, Joseph R., Duan, Dayue, Collier, Mei Lin, Yamazaki, Jun, Horowitz, Burton. Anion Transport in Heart. Physiological reviews, vol.80, no.1, 31-81.

상세보기
Am. J. Physiol. HUSTED R.F. F433 271 1996 Separate regulation of Na and anion transport by IMCD: location, aldosterone, hypertonicity, TGF‐beta1 and cAMP
Husted, R F, Volk, K A, Sigmund, R D, Stokes, J B. Anion secretion by the inner medullary collecting duct. Evidence for involvement of the cystic fibrosis transmembrane conductance regulator.. The Journal of clinical investigation, vol.95, no.2, 644-650.

상세보기
Am. J. Physiol. HUSTED R.F. F946 275 1998 Concerted actions of IL‐1beta inhibit Na absorption and stimulate anion secretion by IMCD cells
Am. J. Physiol. KIZER N.L. F347 268 1995 Electrogenic sodium absorption and chloride secretion by an inner medullary collecting duct cell line (mIMCD‐K2)
J. Gen. Physiol. KUMURA A. 59 115 2000 10.1085/jgp.115.1.59 Bimodal control of a Ca2+ activated Cl− channel by different Ca2+ signals

상세보기
Lee, D., Ha, S., Kho, Y., Kim, J., Cho, K., Baik, M., Choi, Y.. Induction of Mouse Ca²⁺-Sensitive Chloride Channel 2 Gene during Involution of Mammary Gland. Biochemical and biophysical research communications, vol.264, no.3, 933-937.

상세보기
Margolius, H S. The Kallikrein-Kinin System and the Kidney. Annual review of physiology, vol.46, 309-326.

상세보기
McCoy, David E., Taylor, Amanda L., Kudlow, Brian A., Karlson, Katherine, Slattery, Margaret J., Schwiebert, Lisa M., Schwiebert, Erik M., Stanton, Bruce A.. Nucleotides regulate NaCl transport in mIMCD-K2 cells via P2X and P2Y purinergic receptors. American journal of physiology. Renal physiology, vol.277, no.4, F552-F559.

상세보기
Am. J. Physiol. MUKAI H. R352 271 1996 Bradykinin B2 receptor antagonist increases chloride and water absorption in rat medullary collecting duct
Am. J. Physiol. ROCHA A.S. F265 259 1990 Atrial peptide and cGMP effects on NaCl transport in inner medullary collecting duct
Rocha, Antonino S., Kudo, Lúcia H.. Factors governing sodium and chloride transport across the inner medullary collecting duct. Kidney international, vol.38, no.4, 654-667.

상세보기
Romio, L., Musante, L., Cinti, R., Seri, M., Moran, O., Zegarra-Moran, O., Galietta, L.J.V.. Characterization of a murine gene homologous to the bovine CaCC chloride channel. Gene, vol.228, no.1, 181-188.

상세보기
Int. J. Mol. Med. SCHANSTRA J.P. 185 3 1999 Renal bradykinin receptors: Localisation, transduction pathways and molecular basis for a possible pathological role
10.1016/S0070-2161(08)60825-4
Simmons, N L. Acetylcholine and kinin augmentation of Cl‐ secretion stimulated by prostaglandin in a canine renal epithelial cell line.. The Journal of physiology, vol.447, 1-15.

상세보기
Simmons, NL. Renal epithelial Cl‐ secretion. Experimental physiology, vol.78, no.2, 117-137.

상세보기
Siragy, Helmy M., Jaffa, Ayad A., Margolius, Harry S.. Bradykinin B ₂ Receptor Modulates Renal Prostaglandin E ₂ and Nitric Oxide. Hypertension, vol.29, no.3, 757-762.

상세보기
Song, Qing, Chao, Julie, Chao, Lee. High Level of Circulating Human Tissue Kallikrein Induces Hypotension in a Transgenic Mouse Model. Clinical and experimental hypertension : CHE, vol.18, no.8, 975-993.

상세보기
Vandorpe, D. H., Ciampolillo, F., Green, R. B., Stanton, B. A.. Cyclic nucleotide-gated cation channels mediate sodium absorption by IMCD (mIMCD-K2) cells. American journal of physiology. Cell physiology, vol.272, no.3, C901-C910.

상세보기
Vandorpe, D., Kizer, N., Ciampollilo, F., Moyer, B., Karlson, K., Guggino, W. B., Stanton, B. A.. CFTR mediates electrogenic chloride secretion in mouse inner medullary collecting duct (mIMCD-K2) cells. American journal of physiology. Cell physiology, vol.269, no.3, C683-C689.

상세보기
Biol. Res. VIO C.P. 305 31 1998 Cellular and functional aspects of the renal kallikrein system in health and disease
Winpenny, J. P., Harris, A., Hollingsworth, M. A., Argent, B. E., Gray, M. A.. Calcium-activated chloride conductance in a pancreatic adenocarcinoma cell line of ductal origin (HPAF) and in freshly isolated human pancreatic duct cells. Pflügers archiv : European journal of physiology, vol.435, no.6, 796-803.

상세보기
Winpenny, J. P., Verdon, B., McAlroy, H. L., Colledge, W. H., Ratcliff, R., Evans, M. J., Gray, M. A., Argent, B. E.. Calcium-activated chloride conductance is not increased in pancreatic duct cells of CF mice. Pflügers archiv : European journal of physiology, vol.430, no.1, 26-33.

상세보기
Wirth, K., Hock, F.J., Albus, U., Linz, W., Alpermann, H.G., Anagnostopoulos, H., Henke, St., Breipohl, G., König, W., Knolle, J., Schölkens, B.A.. Hoe 140 a new potent and long acting bradykinin‐antagonist: in vivo studies. British journal of pharmacology : BJP, vol.102, no.3, 774-777.

상세보기
Am. J. Physiol. ZEIDEL M.L. F159 265 1993 Hormonal regulation of inner medullary collecting duct sodium transport

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