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[해외논문] Cloning of Trypanosoma cruzi trans-Sialidase and Expression in Pichia pastoris

Protein expression and purification, v.20 no.3, 2000년, pp.389 - 393  

Laroy, Wouter (Department of Molecular Biology, Unit of Fundamental and Applied Molecular Biology, Ghent University, Flanders Interuniversity Institute for Biotechnology, K. L. Ledeganckstraat 35, B-9000, Ghent, Belgium) ,  Contreras, Roland (Department of Molecular Biology, Unit of Fundamental and Applied Molecular Biology, Ghent University, Flanders Interuniversity Institute for Biotechnology, K. L. Ledeganckstraat 35, B-9000, Ghent, Belgium)

Abstract AI-Helper 아이콘AI-Helper

Abstract Trypanosoma cruzi, the agent causing Chagas' disease, expresses an enzyme that transfers sialic acids among glycoproteins and glycolipids both from the host cell surface and its own surface. This enzyme, called trans-sialidase, is different from higher eukaryotic sialyltransferases in tha...

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참고문헌 (27)

  1. Annu. Rev. Microbiol. Brener 27 347 1973 10.1146/annurev.mi.27.100173.002023 Biology of Trypanosoma cruzi 

  2. Science Pereira 219 1444 1983 10.1126/science.6338592 A developmentally regulated neuraminidase activity in Trypanosoma cruzi 

  3. Parasitology Frasch 108 S37 1994 10.1017/S0031182000075703 Trans-sialidase, SAPA amino acid repeats and the relationship between Trypanosoma cruzi and the mammalian host 

  4. Mol. Biochem. Parasitol. Previato 16 85 1985 10.1016/0166-6851(85)90051-9 Incorporation of sialic acid into Trypanosoma cruzi macromolecules. A proposal for a new metabolic route 

  5. Cell Schenkman 65 1117 1991 10.1016/0092-8674(91)90008-M A novel cell surface trans-sialidase of Trypanosoma cruzi generates a stage-specific epitope required for invasion of mammalian cells 

  6. Mol. Biochem. Parasitol. Engstler 61 1 1993 10.1016/0166-6851(93)90153-O The developmentally-regulated trans-sialidase from trypanosoma-brucei sialylates the procyclic acidic repetitive protein 

  7. Acta Trop. Engstler 59 117 1995 10.1016/0001-706X(95)00077-R Distribution of developmentally regulated trans-sialidases in the Kinetoplastida and characterization of a shed trans-sialidase activity from procyclic Trypanosoma congolense 

  8. Mol. Biochem. Parasitol. Medina-Acosta 64 273 1994 10.1016/0166-6851(94)00029-8 Combined occurrence of trypanosomal sialidase/trans-sialidase activities and leishmanial metalloproteinase gene homologues in Endotrypanum sp 

  9. Parasitol. Today Schenkman 9 218 1993 10.1016/0169-4758(93)90017-A Trypanosoma Cruzi trans-sialidase and cell invasion 

  10. Schenkman 239 1999 Sialobiology and Other Novel Forms of Glycosylation Structure and function of Trypanosoma cruzi trans-sialidase and sialic acid receptors 

  11. J. Eukaryotic Microbiol. Hall 40 207 1993 10.1111/j.1550-7408.1993.tb04905.x Developmentally-regulated virulence factors of Trypanosoma-cruzi and their relationship to evasion of host defenses 

  12. J. Exp. Med. Chuenkova 181 1693 1995 10.1084/jem.181.5.1693 Trypanosoma cruzi trans-sialidase: Enhancement of virulence in a murine model of Chagas' disease 

  13. J. Exp. Med. Pereira 174 179 1991 10.1084/jem.174.1.179 The Trypanosoma cruzi neuraminidase contains sequences similar to bacterial neuraminidases, YWTD repeats of low density lipoprotein receptor, and type III modules of fibronectin 

  14. EMBO J. Uemura 11 3837 1992 10.1002/j.1460-2075.1992.tb05476.x Only some members of a gene family in Trypanosoma cruzi encode proteins that express both trans-sialidase and neuraminidase activities 

  15. Gene Cremona 160 123 1995 10.1016/0378-1119(95)00175-6 A single tyrosine differentiates active and inactive Trypanosoma cruzi trans-sialidases 

  16. Mol. Biochem. Parasitol. Egima 77 115 1996 10.1016/0166-6851(96)02582-0 Organization of trans-sialidase genes in Trypanosoma cruzi 

  17. J. Biol. Chem. Schenkman 269 7970 1994 10.1016/S0021-9258(17)37146-6 A proteolytic fragment of Trypanosoma cruzi trans-sialidase lacking the carboxyl-terminal domain is active, monomeric, and generates antibodies that inhibit enzymatic activity 

  18. Blood Buscaglia 93 2025 1999 10.1182/blood.V93.6.2025.406k19_2025_2032 Tandem amino acid repeats from Trypanosoma cruzi shed antigens increase the half-life of proteins in blood 

  19. EMBO J. Buschiazzo 19 16 2000 10.1093/emboj/19.1.16 Structural basis of sialyltransferase activity in trypanosomal sialidases 

  20. J. Infect. Dis. Leguizamon 180 1398 1999 10.1086/315001 trans-Sialidase from Trypanosoma cruzi induces apoptosis in cells from the immune system in vivo 

  21. Cell. Mol. Biol. Buschiazzo 42 703 1996 Medium scale production and purification to homogeneity of a recombinant trans-sialidase from Trypanosoma cruzi 

  22. Biochem. Biophys. Res. Commun. Chuenkova 262 549 1999 10.1006/bbrc.1999.1154 trans-sialidase of Trypanosoma cruzi: Location of galactose-binding site(s) 

  23. Mol. Biochem. Parasitol. Campetella 64 337 1994 10.1016/0166-6851(94)00036-0 A recombinant Trypanosoma cruzi trans-sialidase lacking the amino acid repeats retains the enzymatic activity 

  24. Proc. Natl. Acad. Sci. USA Sanger 74 5463 1977 10.1073/pnas.74.12.5463 DNA sequencing with chain-terminating inhibitors 

  25. Sambook 1989 Molecular Cloning: A Laboratory Manual 

  26. Anal. Biochem. Bradford 7 248 1976 10.1016/0003-2697(76)90527-3 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding 

  27. Nature Laemmli 227 680 1970 10.1038/227680a0 Cleavage of structural proteins during the assembly of the head of bacteriophage T4 

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