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[해외논문] Hematopoietic Expression of Hoxb4 Is Regulated in Normal and Leukemic Stem Cells through Transcriptional Activation of the Hoxb4 Promoter by Upstream Stimulating Factor (Usf)-1 and Usf-2

The Journal of experimental medicine, v.192 no.10, 2000년, pp.1479 - 1490  

Giannola, Diane M. (Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104) ,  Shlomchik, Warren D. (Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06510) ,  Jegathesan, Mithila (Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104) ,  Liebowitz, David (Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104) ,  Abrams, Charles S. (Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104) ,  Kadesch, Tom (Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania 19104) ,  Dancis, Andrew (Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104) ,  Emerson, Stephen G. (Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104)

Abstract AI-Helper 아이콘AI-Helper

The homeobox genes encode a family of transcription factors that regulate development and postnatal tissue homeostasis. Since HOXB4 plays a key role in regulating the balance between hematopoietic stem cell renewal and differentiation, we studied the molecular regulation of HOXB4 expression in human...

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