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[해외논문] Nuclear organization of DNA replication in primary mammalian cells 원문보기

Genes & development, v.14 no.22, 2000년, pp.2855 - 2868  

Kennedy, Brian K. ,  Barbie, David A. ,  Classon, Marie ,  Dyson, Nicholas ,  Harlow, Ed

Abstract AI-Helper 아이콘AI-Helper

Using methods that conserve nuclear architecture, we have reanalyzed the spatial organization of the initiation of mammalian DNA synthesis. Contrary to the commonly held view that replication begins at hundreds of dispersed nuclear sites, primary fibroblasts initiate synthesis in a limited number of...

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