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Genes & development, v.14 no.22, 2000년, pp.2855 - 2868
Kennedy, Brian K. , Barbie, David A. , Classon, Marie , Dyson, Nicholas , Harlow, Ed
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Using methods that conserve nuclear architecture, we have reanalyzed the spatial organization of the initiation of mammalian DNA synthesis. Contrary to the commonly held view that replication begins at hundreds of dispersed nuclear sites, primary fibroblasts initiate synthesis in a limited number of...
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