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[해외논문] Limitation of Infarct Size in Rabbit Hearts by the Novel Adenosine Receptor Agonist AMP 579 Administered at Reperfusion

Journal of molecular and cellular cardiology, v.32 no.12, 2000년, pp.2339 - 2347  

Xu, Zhelong (Department of Physiology, University of South Alabama, College of Medicine, Mobile, AL 36688, USA) ,  Yang, Xi-Ming (Department of Physiology, University of South Alabama, College of Medicine, Mobile, AL 36688, USA) ,  Cohen, Michael V (Department of Physiology, University of South Alabama, College of Medicine, Mobile, AL 36688, USA) ,  Neumann, Till (Department of Pathophysiology, University of Essen, Essen, Germany) ,  Heusch, Gerd (Department of Physiology, University of South Alabama, College of Medicine, Mobile, AL 36688, USA) ,  Downey, James M (Department of Physiology, University of South Alabama, College of Medicine, Mobile, AL 36688, USA)

Abstract AI-Helper 아이콘AI-Helper

AbstractThe novel A1/A2adenosine receptor agonist AMP 579 has been reported to reduce myocardial infarct size in pig and dog. The present study tested the effect of AMP 579 in two rabbit models. In open-chest rabbits undergoing 30 min of regional ischemia and 3 h of reperfusion AMP 579 (3 μ g...

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참고문헌 (25)

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  2. Circulation Thornton 85 659 1992 10.1161/01.CIR.85.2.659 Intravenous pretreatment with A1-selective adenosine analogues protects the heart against infarction 

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  6. Cardiovasc Res Goto 25 943 1991 10.1093/cvr/25.11.943 Adenosine infusion during early reperfusion failed to limit myocardial infarct size in a collateral deficient species 

  7. Cardiovasc Res Vander Heide 31 711 1996 10.1016/S0008-6363(95)00235-9 Effect of adenosine therapy at reperfusion on myocardial infarct size in dogs 

  8. J Pharmacol Exp Ther Smits 286 611 1998 Cardioprotective effects of the novel adenosine A1/A2receptor agonist AMP 579 in a porcine model of myocardial infarction 

  9. J Cardiovasc Pharmacol McVey 33 703 1999 10.1097/00005344-199905000-00005 Cardiovascular pharmacology of the adenosine A1/A2-receptor agonist AMP 579: coronary hemodynamic and cardioprotective effects in the canine myocardium 

  10. Am J Physiol Jordan 277 H1895 1999 A3adenosine receptor activation attenuates neutrophil function and neutrophil-mediated reperfusion injury 

  11. J Mol Cell Cardiol Shirato 21 1187 1989 10.1016/0022-2828(89)90695-0 Tetrazolium artifactually indicates superoxide dismutase-induced salvage in reperfused rabbit heart 

  12. Basic Res Cardiol Miki 94 180 1999 10.1007/s003950050141 Failure of N-2-mercaptopropionyl glycine to reduce myocardial infarction after 3 days of reperfusion in rabbits 

  13. Washington: National Academy Press National Research Council 1996 Guide for the care and use of laboratory animals 

  14. Circulation Weinbrenner 98 899 1998 10.1161/01.CIR.98.9.899 Fostriecin, an inhibitor of protein phosphatase 2A, limits myocardial infarct size even when administered after onset of ischemia 

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  18. Cardiovasc Res Budde 47 294 2000 10.1016/S0008-6363(00)00115-2 Comparative study of AMP579 and adenosine in inhibition of neutrophil-mediated vascular and myocardial injury during 24 h of reperfusion 

  19. Circulation Baxter 102 (Suppl. II) II 2000 Amp579, an A1/A2A agonist, limits infarct size at reperfusion via a P42/P44 MAPK-dependent pathway (Abstract) 

  20. Circulation Murry 74 1124 1986 10.1161/01.CIR.74.5.1124 Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium 

  21. Circulation Liu 84 350 1991 10.1161/01.CIR.84.1.350 Protection against infarction afforded by preconditioning is mediated by A1adenosine receptors in rabbit heart 

  22. Cardiovasc Res Tsuchida 26 456 1992 10.1093/cvr/26.5.456 Role of adenosine receptor activation in myocardial infarct size limitation by ischaemic preconditioning 

  23. J Mol Cell Cardiol Grover 32 677 2000 10.1006/jmcc.2000.1111 ATP-sensitive potassium channels: a review of their cardioprotective pharmacology 

  24. J Mol Cell Cardiol Zhao 24 (Suppl. III) S.8 1992 Receptor-mediated reduction of myocardial infarct size and attenuated no-reflow by endogIenous adenosine during ischemia and reperfusion (Abstract) 

  25. J Cardiovasc Electrophysiol Baines 10 741 1999 10.1111/j.1540-8167.1999.tb00251.x Signal transduction in ischemic preconditioning: the role of kiInases and mitochondrial KATPchannels 

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